Northeast Missouri, MO Vacation Homes from ￥17,077

A large eye sculpture in a park surrounded by trees.

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Our top choices for Northeast Missouri vacation homes

A living room with a brown sofa, a wooden coffee table, a television on a stand, and a bookshelf.

1. Unwind on Vine

Macon

Nancy E.

￥26,932 total

includes taxes & fees

Oct 1 - Oct 2

A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

2. Aunt Lele's Cozy Cottage

Quincy

Matt B.

￥26,000 total

includes taxes & fees

Oct 11 - Oct 12

A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

3. Peaceful, Country Cottage with Open Floor Plan

Quincy

Vicki W.

￥38,738 total

includes taxes & fees

Oct 4 - Oct 5

A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

4. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Hannibal

Lisa B.

￥29,280 total

includes taxes & fees

Sep 28 - Sep 29

A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

5. Vibey home a few blocks from downtown Hannibal

Hannibal

Shaun P.

￥43,831 total

includes taxes & fees

Sep 23 - Sep 24

A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

6. Modern and comfy home five minutes from downtown

Hannibal

Brent W.

￥45,165 total

includes taxes & fees

Sep 23 - Sep 24

A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

7. Spacious & Modern 2BR Home with Attached Garage

Quincy

Marsha

￥38,190 total

includes taxes & fees

Oct 18 - Oct 19

8. Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Imperial

Tommy H.

￥17,077 total

includes taxes & fees

Sep 23 - Sep 24

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Top Northeast Missouri Hotel Reviews

Courtyard by Marriott St. Louis Downtown/Convention Center

8/10 Good

"The portions of the hotel that we used (room, check out desk, elevator, common hallways) were very clean, one of the most important aspects of our stay. Most of the staff were very helpful and accommodating. We are used to staying at a hotel chain that provides an included breakfast. We found the Bistro prices awfully high and chose to eat at local breakfast eateries instead. We also usually park our car in the hotel parking lot, but our choices here were to pay for valet parking at $48 a day, or self park in a structure a block away for $40 a night. The total cost for parking was more than one night of our stay. The combination of those two extra expenses soured my experience a bit and is the reason for a 4-star rating."

Pear Tree Inn St. Louis Near Union Station

8/10 Good

"Stay was good, room was clean. When we went to our room it was an unseasonably hot day and our room was 80 and the ac was blowing warm air. I went down and told the front desk and gentleman behind the desk snapped back at me saying it just needs reset and they would send someone up. Well… they never did. Thankfully my husband is handy and he was able to reset it so our room could cool down otherwise we would have been miserable all night."

Clayton Plaza Hotel & Extended Stay

8/10 Good

"An older, historic-looking hotel with character in a nice, walkable, safe area. I loved that my room was very well insulated and actually sound-proof from most street noise or human sounds inside the building. The furniture was old, with some looking original to the building. The breakfast was the highlight, with an incredible omelet station with fresh ingredients and a knowledgeable, friendly person creating the omelets. The breakfast is better than most complimentary hotel breakfasts. The staff were friendly, helpful and always seemed to be cleaning or helping customers. The exercise room was large, clean and well-equipped. The air-conditioners worked very well, thank goodness. My only suggestion is for housekeeping to be a little more careful cleaning room floor. I wore black socks in my room and by the end of the evening they were covered with debris should have been swept up from many prior occupants. The parking was easy and affordable at $6 per day; however, it ended up being free of charge since the automatic arms at the entrance were always up during my stay. The bathroom clearly had been completely updated and looks very nice with two showers. The in-room fridge and microwave were helpful. If I am in the St. Louis area I will plan to stay here again."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Excellent front desk staff,very friendly and helpful..We arrived in time for free evening snacks and drinks..Room was very comfortable and roomy..Airport shuttle is a added plus, we used long term parking for our trip and it was very convenient, the shuttle delivered us right to our car on return..highly recommend Pear Tree Inn for your stay!!"

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"We enjoyed our time in the Arts Roof Bar and breakfast in Commonwealth, a restaurant on street level. We also had dinner at Commonwealth and the scallops were great. We love this hotel. We walked across the street to the symphony and on others stays I visited 3 art galleries with in an easy walk. The best part is the room that is saturated in the color you choose. Our room was blue with a great view."

Find out more about Northeast Missouri

Northeast Missouri Vacation Homes information

Number of reviews	1,359
Accommodation	612 Vacation Homes
Lowest Price	￥17,077
Highest Price	￥57,517

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Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Northeast Missouri vacation homes

1. Unwind on Vine

2. Aunt Lele's Cozy Cottage

3. Peaceful, Country Cottage with Open Floor Plan

4. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

5. Vibey home a few blocks from downtown Hannibal

6. Modern and comfy home five minutes from downtown

7. Spacious & Modern 2BR Home with Attached Garage

8. Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

9. Cozy little house blocks from the Park & Fair Grounds.

10. Unique Tiny Home! Lakefront ~ BBQ Grill ~ Couple's Retreat

11. Gipfel Suite - Himmel Haus Bed & Breakfast

12. The John Sydney House - Family and Pet Friendly Historic Home Downtown

13. TJ’s Country Getaway- Dog Friendly

14. Our 80-Acre Farm, Lake, Nature Trail, Bonfires, Starry Nights 2 Miles Grafton

15. Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

16. Secluded 2 bedroom home close to Hermann

17. WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

18. Settle into Soulard! 6 beds 2 full baths!

19. Centrally located in the Tower Grove East neighborhood!

20. 3-bedroom family friendly home on 4 acres near Hermann with WiFi, AC, deck

Find vacation rentals that suit your style

Top Northeast Missouri Hotel Reviews

Courtyard by Marriott St. Louis Downtown/Convention Center

Pear Tree Inn St. Louis Near Union Station

Renaissance St. Louis Airport Hotel

Drury Plaza Hotel St. Louis Union Station

Clayton Plaza Hotel & Extended Stay

Pear Tree Inn St. Louis Airport

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Live by Loews - St.Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Find out more about Northeast Missouri

Northeast Missouri Vacation Homes information

Explore a world of travel with Expedia

Search Vacation Homes in Northeast Missouri

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Northeast Missouri vacation homes

1. Unwind on Vine

2. Aunt Lele's Cozy Cottage

3. Peaceful, Country Cottage with Open Floor Plan

4. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

5. Vibey home a few blocks from downtown Hannibal

6. Modern and comfy home five minutes from downtown

7. Spacious & Modern 2BR Home with Attached Garage

8. Charming 1-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

9. Cozy little house blocks from the Park & Fair Grounds.

10. Unique Tiny Home! Lakefront ~ BBQ Grill ~ Couple's Retreat

11. Gipfel Suite - Himmel Haus Bed & Breakfast

12. The John Sydney House - Family and Pet Friendly Historic Home Downtown

13. TJ’s Country Getaway- Dog Friendly

14. Our 80-Acre Farm, Lake, Nature Trail, Bonfires, Starry Nights 2 Miles Grafton

15. Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

16. Secluded 2 bedroom home close to Hermann

17. WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

18. Settle into Soulard! 6 beds 2 full baths!

19. Centrally located in the Tower Grove East neighborhood!

20. 3-bedroom family friendly home on 4 acres near Hermann with WiFi, AC, deck

Find vacation rentals that suit your style

Top Northeast Missouri Hotel Reviews

Courtyard by Marriott St. Louis Downtown/Convention Center

Find out more about Northeast Missouri

Northeast Missouri Vacation Homes information

Explore a world of travel with Expedia