A large eye sculpture in a park surrounded by trees.

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Check prices for these dates

In two weeks
Oct 23 - Oct 25
In two months
Dec 4 - Dec 6
In three months
Jan 1 - Jan 3
In four months
Jan 29 - Jan 31

Our top choices for Northeast Missouri vacation homes

A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

1. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (46 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
The price is ￥10,659
￥24,749 total
includes taxes & fees
Oct 11 - Oct 12
Aunt Lele's Cozy Cottage
A living room with a brown sofa, a wooden coffee table, a television on a stand, and a bookshelf.

2. Unwind on Vine

Unwind on Vine
Macon
9.6 out of 10, Exceptional, (37 reviews)
"We have stayed twice at Unwind on the Vine and have enjoyed our stays. The owners are very attentive to any needs we have had during our stays."
United States
Nancy E.
The price is ￥23,450
￥38,186 total
includes taxes & fees
Oct 8 - Oct 9
Unwind on Vine
A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

3. Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (15 reviews)
"Very Nice house!!! Enjoyed my stay there."
United States
Shaun P.
The price is ￥14,411
￥45,284 total
includes taxes & fees
Oct 8 - Oct 9
Vibey home a few blocks from downtown Hannibal
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

4. Spacious & Modern 2BR Home with Attached Garage

Spacious & Modern 2BR Home with Attached Garage
Quincy
10.0 out of 10, Exceptional, (53 reviews)
"Nicely decorated and very comfortable."
United States
Marsha
The price is ￥16,896
￥35,278 total
includes taxes & fees
Oct 19 - Oct 20
Spacious & Modern 2BR Home with Attached Garage
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

5. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (224 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
The price is ￥20,528
￥38,992 total
includes taxes & fees
Oct 13 - Oct 14
Peaceful, Country Cottage with Open Floor Plan
A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

6. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (67 reviews)
"Great location for downtown exploring."
United States
Lisa B.
The price is ￥17,874
￥29,627 total
includes taxes & fees
Nov 3 - Nov 4
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

7. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.8 out of 10, Exceptional, (24 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
The price is ￥26,576
￥40,230 total
includes taxes & fees
Oct 8 - Oct 9
The John Sydney House - Family and Pet Friendly Historic Home Downtown
A covered patio with string lights, a seating area, and a small table.

8. TJ’s Country Getaway- Dog Friendly

TJ’s Country Getaway- Dog Friendly
Union
10.0 out of 10, Exceptional, (51 reviews)
"Best solo stay VRBO I've experienced. Quaint location; immaculately maintained/clean; bedding and bathroom accommodations excellent; any and everything needed in kitchenette; good wifi and tv; etc... Special place for dog lovers. Nice host!"
United States
Kelly S.
The price is ￥11,843
￥26,071 total
includes taxes & fees
Oct 26 - Oct 27
TJ’s Country Getaway- Dog Friendly
A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

9. Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (21 reviews)
"House was perfect for our stay."
United States
Brent W.
The price is ￥15,519
￥46,709 total
includes taxes & fees
Oct 11 - Oct 12
Modern and comfy home five minutes from downtown
A modern kitchen with wooden cabinets, stainless steel appliances, and a large island with bar stools.

10. Shouse Near Mark Twain Lake!

Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (13 reviews)
"This was our second stay, and it was just as great as the first time! Plenty of room to play, huge TVs for family movie night, and a well equipped kitchen for serving meals. Thank you! "
United States
Christina H.
The price is ￥36,319
￥51,657 total
includes taxes & fees
Oct 8 - Oct 9
Shouse Near Mark Twain Lake!
A modern kitchen with white cabinets, a stainless steel oven, a microwave, and a refrigerator. There is a dining table with chairs and a ceiling fan.

11. Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (200 reviews)
"Great spot and the wife loved the locationWould recommend highly"
United States
Julio B.
The price is ￥13,501
￥24,027 total
includes taxes & fees
Oct 19 - Oct 20
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
Property grounds

12. Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors

Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
Imperial
9.8 out of 10, Exceptional, (8 reviews)
"Thank you we enjoyed the place but we would like to get some more nights if all possible"
United States
Tommy H.
The price is ￥12,080
￥18,671 total
includes taxes & fees
Oct 8 - Oct 9
Charming 2-bedroom house in nice Imperial with AC. Attn! Traveling Contractors
A porch with two turquoise Adirondack chairs and a small table, surrounded by well-maintained greenery and a white house with black shutters.

13. WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Augusta
10.0 out of 10, Exceptional, (41 reviews)
"Comfortable place to stay. We appreciated the snacks and that there is a pack n play!"
United States
Samantha E.
The price is ￥25,739
￥46,127 total
includes taxes & fees
Oct 13 - Oct 14
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
A modern living room with a sofa, a wooden dining table with stools, a kitchen area with cabinets and a TV, and a hallway leading to a door.

14. Family friendly 3 bedroom home in Kahoka MO

Family friendly 3 bedroom home in Kahoka MO
Kahoka
9.2 out of 10, Wonderful, (12 reviews)
"Absolutely friendly and welcoming hosts. "
United States
Jay M.
The price is ￥22,739
￥34,840 total
includes taxes & fees
Oct 12 - Oct 13
Family friendly 3 bedroom home in Kahoka MO
A dining area with a wooden table, grey upholstered chairs, a bench, a patterned rug, a brick wall, a framed picture, and a potted plant.

15. Centrally located in the Tower Grove East neighborhood!

Centrally located in the Tower Grove East neighborhood!
Tower Grove East
9.8 out of 10, Exceptional, (178 reviews)
"Great place!"
United States
Arthur S.
The price is ￥12,633
￥26,366 total
includes taxes & fees
Oct 19 - Oct 20
Centrally located in the Tower Grove East neighborhood!
A kitchen with a microwave, stove, and refrigerator. There is a dining area with a table and chairs.

16. Large home, Pet friendly

Large home, Pet friendly
Union
9.8 out of 10, Exceptional, (41 reviews)
"This is the second time we have stayed at this home. Great place. Thank you for the hospitality."
United States
Nadine I.
The price is ￥28,424
￥63,681 total
includes taxes & fees
Oct 8 - Oct 9
Large home, Pet friendly
A living room with a wooden entertainment center, a white sofa, and a dining area with a white railing.

17. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (45 reviews)
"Very clean. We had a nice stay."
United States
John V.
The price is ￥25,581
￥42,687 total
includes taxes & fees
Oct 13 - Oct 14
Spacious, cozy home in Saint Louis
Eat in Kitchen for 6 with granite counters and stainless appliances

18. Historic Craftsman • Hot Tub • Walk to Wineries • Katy Trail

Historic Craftsman • Hot Tub • Walk to Wineries • Katy Trail
AUGUSTA
10.0 out of 10, Exceptional, (7 reviews)
"We had a great stay! The property is within walking distance of several shops & a cute cafe. The owner was very responsive."
United States
Claire M.
The price is ￥29,595
￥67,751 total
includes taxes & fees
Oct 13 - Oct 14
Historic Craftsman • Hot Tub • Walk to Wineries • Katy Trail
A two-story house with a covered porch, a stone facade, and a well-maintained lawn.

19. Kid and pet friendly 2 nd floor duplex

Kid and pet friendly 2 nd floor duplex
Pacific
9.0 out of 10, Wonderful, (30 reviews)
"The house was clean and comfortable. Would stay there again."
United States
Jason T.
The price is ￥24,516
￥31,222 total
includes taxes & fees
Oct 8 - Oct 9
Kid and pet friendly 2 nd floor duplex
A living room with a TV, wooden furniture, a fireplace, and a cozy seating area.

20. Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi

Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi
Bevo Mill
9.0 out of 10, Wonderful, (37 reviews)
"We enjoyed our stay, very quaint house and Julie was an amazing host "
United States
Lori O.
The price is ￥18,791
￥39,438 total
includes taxes & fees
Oct 13 - Oct 14
Charming 2-bedroom, cozy bungalow with sunroom in fabulous St. Louis with WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Northeast Missouri Hotel Reviews

21C Museum Hotel St Louis

21C Museum Hotel St Louis

8/10 Good
"Great location. Parking is expensive unless you can find street parking. It is a really neat old building make sure you walk around! We had a weird light that would not turn off I our room. Maintenance came and had to put tape and cardboard over it. Effective but not a long term solution for dum design"
Stephanie 1-night trip
Posted 1 hour ago
21C Museum Hotel St Louis

Find out more about Northeast Missouri

Northeast Missouri Vacation Homes information

Number of reviews
719
Accommodation
630 Vacation Homes
Lowest Price
￥18,671
Highest Price
￥67,751

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