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Check availability on Mytilene Luxury Hotels

This weekend
May 29 - May 31
Next weekend
Jun 5 - Jun 7

Our top choices for Mytilene luxury hotels

Free daily continental breakfast

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
4.0 star property
Lesvos
9.6 out of 10, Exceptional, (162 reviews)
  • cleanliness
    Luxuriate in this Lesvos boutique haven where pillowtop beds meet spa indulgences, all within steps of the beach and local art.
The price is ￥21,408
￥25,299 total
includes taxes & fees
Jun 1 - Jun 2
Theofilos Paradise Boutique Hotel
Garden

The Loriet

The Loriet
4.0 star property
Lesvos
8.4 out of 10, Very Good, (82 reviews)
The price is ￥17,306
￥20,804 total
includes taxes & fees
Jun 8 - Jun 9
The Loriet
Seasonal outdoor pool

Heliotrope Hotels

Heliotrope Hotels
4.0 star property
Lesvos
8.6 out of 10, Excellent, (197 reviews)
The price is ￥12,702
￥15,762 total
includes taxes & fees
May 31 - Jun 1
Heliotrope Hotels
Exterior

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
5.0 star property
Lesvos
8.6 out of 10, Excellent, (47 reviews)
  • cleanliness
    Seaside luxury awaits at this Greek retreat, where beachfront bliss meets wellness indulgence with 3 indoor pools and a full-service spa.
The price is ￥22,779
￥27,723 total
includes taxes & fees
Jun 2 - Jun 3
Mythical Coast Wellness Retreat
Terrace/patio

Elysion Hotel

Elysion Hotel
5.0 star property
Lesvos
9.2 out of 10, Wonderful, (46 reviews)
  • cleanliness
    Experience tranquil luxury and refined comfort at this 5-star seaside retreat with outdoor tennis courts and multiple dining options.
The price is ￥19,347
￥23,965 total
includes taxes & fees
Jun 1 - Jun 2
Elysion Hotel
Reception

Aeolian Gaea Hotel

Aeolian Gaea Hotel
4.0 star property
Lesvos
9.6 out of 10, Exceptional, (8 reviews)
Aeolian Gaea Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mytilene Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Mytilene vacation?
Mytilene has some interesting things to see and do including Port of Mytilene and Mytilini Castle, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Mytilene?
Theofilos Paradise Boutique Hotel is a luxury hotel with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Mythical Coast Wellness Retreat and Elysion Hotel are two other upscale options for your trip.
When can I expect good weather in Mytilene?
Planning for the weather is a good way to make your trip to Mytilene relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 77°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Mytilene is 34 inches.
What's there to see and do in Mytilene?
Take in the sights and attractions that Mytilene offers with a visit to Port of Mytilene, Mytilini Castle, and Thermi Beach. If you have a little extra time during your trip, you might want to make a stop at Roman Aqueduct at Moria and Thermes Gera Hot Springs.