Melrose Vacation Rentals

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Our top choices for Melrose vacation rentals

Cabin in Trempealeau

Toddy's Cabin
10.0 out of 10, Exceptional, (127)
"Clean and comfortable property! "
United States
nicole w.
Toddy's Cabin
9.8 out of 10, Exceptional, (81)
"It was a great property and clean place to stay"
United States
janessa r.
Tall Pines Lodge- Cottages On Serenity Lake- Sitting on 80 Acres Of Wildlife!

Vacation Home in Northside

River Front Property
9.8 out of 10, Exceptional, (106)
"Great stay "
United States
Koby K.
River Front Property

Vacation Home in Black River Falls

Luxury Private Estate
9.6 out of 10, Exceptional, (81)
"Great place for family gathering "
United States
Heather M.
Luxury Private Estate
10.0 out of 10, Exceptional, (51)
"Quiet and great location."
United States
Jeremy S.
Spacious Dog-Friendly 5BR Near UWL w/ Fire Pit & Fenced Yard

Cabin in Trempealeau

Cabin on the Mississippi River
10.0 out of 10, Exceptional, (92)
"Long weekend to celebrate Anniversary! Just enojoyed the river views!"
United States
Kendra H.
Cabin on the Mississippi River
10.0 out of 10, Exceptional, (188)
"Absolutely AMAZING property! Everyone in our group enjoyed our stay. Lots of space and everything you need in a home away from home. We will definitely be back again. "
United States
April B.
Gorgeous Log Home featuring 8-person outdoor HOT TUB-available year round.
10.0 out of 10, Exceptional, (133)
"Our third time here, and it’s always a great stay! "
United States
Brian G.
Enjoy this 2 bedroom, 1 bath, cozy lake side house located on Lake Onalaska.
9.6 out of 10, Exceptional, (124)
"Host was amazing an very proactive to make sure we were a comfortable an content, very clean an couldn’t ask for much else"
United States
Austin K.
Bear's Den- Cottages On Serenity Lake- Beautiful Cottage On Small, Private Lake!
10.0 out of 10, Exceptional, (10)
"Wonderful property- there were so many fun things to do and loved the location."
United States
Sean J.
Waterfront Home with HOT TUB, Large Dock, Game Room, Movie Theater
9.8 out of 10, Exceptional, (46)
"Wonderful stay, super cozy, perfect for a getaway "
United States
Katie C.
The price is ¥13,832
¥24,022 total
includes taxes & fees
Dec 14 - Dec 15
Nostalgic Retro Cottage, Blocks Away from Mississippi River. Full Fenced in Yard

Cottage in Black River Falls

Tiny House on the River
10.0 out of 10, Exceptional, (80)
"The house was beautiful, the fishing was great. It was a wonderful place to relax and reset."
United States
Crystal K.
The price is ¥21,025
¥35,392 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Tiny House on the River
9.6 out of 10, Exceptional, (85)
"Just as described with great communication from host."
United States
Marguerite B.
The Historic A.C. Carter House - River Romance on the La Crosse Historical Tour!

Chalet in West La Crosse

Cozy 8 Person Chalet on the Bay
9.6 out of 10, Exceptional, (7)
"Nice place comfortable relaxing environment, would come back."
United States
Susan
Cozy 8 Person Chalet on the Bay
10.0 out of 10, Exceptional, (4)
"perfect place to stay right in the country with lots to do!"
United States
Keith H.
3-bedroom Lodge with Incredible Game Room and Bar!

Vacation Home in Downtown Trempealeau

The Bungaleau 1 Bedroom House In Cute Rivertown
9.8 out of 10, Exceptional, (90)
"Great location. Has everything you need to stay."
United States
todd s.
The Bungaleau 1 Bedroom House In Cute Rivertown
3.0 star property
3 Mi to Lake Onalaska: Quaint Home w/ Prairie View
9.8 out of 10, Exceptional, (65)
"Second time we have stayed here. We love the house and location. Very accommodating and beautifully renovated "
United States
Lori
A fully remodeled home overlooking Mississippi River in a charming river town!
10.0 out of 10, Exceptional, (16)
"Perfect stay for our group! The cabin had everything we needed, very spacious, and close to the trails! We had a blast and plan to come back next year "
United States
Erica W.
Spacious 3 Story Cabin. Access to UTV/ATV Trails & Near Lake Arbutus
10.0 out of 10, Exceptional, (171)
"Another great stay! Place is amazing and has everything you need."
United States
Ryan H.
Secluded family-friendly log cabin with swimming pond. Charm, comfort.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Melrose Hotel Reviews

Find out more about Melrose

Search for holiday rentals in Melrose on Expedia! You can easily find your home rentals, villas, holiday apartments in Melrose using one of the methods below:

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Frequently asked questions

Can I find vacation rentals in Melrose?

Yes, there are vacation rentals near popular local attractions in Melrose, or you can go with a secluded option if you're looking for a relaxing stay.

What are some of the best vacation home rentals that Melrose has to offer?

River Front Property : Visitors like this Melrose vacation home rental. It is located on a river and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in Melrose?

While exploring the area, visit family-friendly sights like The Craft Barn, or get outside and enjoy nature at LaCrosse River Trail. Jackson County Forestry & Parks and Whitetail Ridge Ski Area are a couple of places you'll find in the larger area.

What’s a vacation rental in Melrose like?

Vacation rentals are private properties you can book for a few weeks or just a few days in Melrose. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the experience of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular choice for families.