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Nov 13 - Nov 14
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Our top choices for Medical District hotels

A hotel room with two beds, each with a patterned bedspread, a nightstand with a lamp, and a wall-mounted light fixture.

1. Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown
2.0 star property
Medical District
5.4 out of 10, (1,005 reviews)
"Parking terrible, TV outdated, staff mediocre"
United States
William
The price is ￥7,809
￥9,592 total
includes taxes & fees
Dec 7 - Dec 8
Motel 6 Memphis, TN - Downtown
A modern hotel with "La Quinta" signage, featuring a prominent entrance and a covered walkway.

2. La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Downtown
3.0 star property
Downtown Memphis, 1.1 km from Medical District
9.2 out of 10, Wonderful, (1,352 reviews)
"clean room, friendly staff and decent breakfast."
United States
Winston
The price is ￥18,429
￥22,112 total
includes taxes & fees
Nov 26 - Nov 27
La Quinta Inn & Suites by Wyndham Memphis Downtown
A hotel reception area with a counter, a fruit display, and a seating area with chairs.

3. Holiday Inn Express Memphis Medical Center Midtown by IHG

Holiday Inn Express Memphis Medical Center Midtown by IHG
2.5 star property
New Pathways, 1.1 km from Medical District
8.4 out of 10, Very good, (1,007 reviews)
"That Southern hospitality was right on point, friendliness at its finest."
United States
Marisol
The price is ￥20,131
￥24,226 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express Memphis Medical Center Midtown by IHG
A multi-story parking garage with a Comfort Inn sign, surrounded by high-rise buildings.

4. Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.9 km from Medical District
8.8 out of 10, Excellent, (1,387 reviews)
"Great breakfast and friendly staff"
United States
Siva
The price is ￥16,173
￥19,526 total
includes taxes & fees
Dec 10 - Dec 11
Comfort Inn Memphis Downtown
A hotel lobby with a reception desk, patterned sofas, and a large window offering a view outside.

5. Best Western Plus Gen X Inn

Best Western Plus Gen X Inn
2.5 star property
New Pathways, 1.1 km from Medical District
7.6 out of 10, Good, (1,001 reviews)
"Everything was perfect and easy to book."
United States
Devin
The price is ￥13,853
￥16,771 total
includes taxes & fees
Dec 6 - Dec 7
Best Western Plus Gen X Inn
An indoor swimming pool with a lifeguard sign, poolside seating, and potted plants.

6. Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street
2.5 star property
Downtown Memphis, 1.6 km from Medical District
8.8 out of 10, Excellent, (1,349 reviews)
"The hotel was in an excellent location. Very safe and close to everthing. The bed was comfortable and the room was spacious."
United States
Laura
The price is ￥19,706
￥23,722 total
includes taxes & fees
Dec 13 - Dec 14
Hampton Inn & Suites Memphis-Beale Street
A spacious lobby with a bar area, multiple seating arrangements, and a decorative fountain.

7. The Peabody Memphis

The Peabody Memphis
5.0 star property
Downtown Memphis, 1.7 km from Medical District
9.4 out of 10, Exceptional, (1,004 reviews)
"Amazing Hotel, would stay there anytime we are in Memphis"
United States
Kenneth D
The price is ￥31,794
￥41,895 total
includes taxes & fees
Nov 22 - Nov 23
The Peabody Memphis
A bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

8. Hilton Garden Inn Memphis Downtown Beale Street

Hilton Garden Inn Memphis Downtown Beale Street
3.0 star property
Downtown Memphis, 1.5 km from Medical District
8.8 out of 10, Excellent, (1,000 reviews)
"Will stay again"
United States
Jessica
The price is ￥19,128
￥23,036 total
includes taxes & fees
Dec 11 - Dec 12
Hilton Garden Inn Memphis Downtown Beale Street
A hotel reception area with a marble counter, potted plants, and a black carpet with a logo.

9. Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.9 km from Medical District
8.4 out of 10, Very good, (2,509 reviews)
"The staff was amazing even during a busy weekend (we stayed Halloween weekend) would deff stay here again :)"
United States
Fatima
The price is ￥13,174
￥16,355 total
includes taxes & fees
Dec 13 - Dec 14
Hu. Hotel
A cityscape with a view of a building with a green roof and a brick facade.

10. Springhill Suites By Marriott Memphis Downtown

Springhill Suites By Marriott Memphis Downtown
3.0 star property
Downtown Memphis, 1.9 km from Medical District
8.4 out of 10, Very good, (1,011 reviews)
"Good location"
Canada
Wes Bryan
The price is ￥18,137
￥21,857 total
includes taxes & fees
Nov 24 - Nov 25
Springhill Suites By Marriott Memphis Downtown
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with sofas and armchairs.

11. Residence Inn by Marriott Memphis Downtown

Residence Inn by Marriott Memphis Downtown
3.0 star property
Downtown Memphis, 1.8 km from Medical District
9.2 out of 10, Wonderful, (1,002 reviews)
"The hotel is in a great location, helpful and friendly staff and spacious rooms."
United States
Katherine
The price is ￥19,987
￥24,055 total
includes taxes & fees
Nov 24 - Nov 25
Residence Inn by Marriott Memphis Downtown
A modern bar area with a curved counter, bar stools, and a central chandelier.

12. Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis
4.0 star property
Downtown Memphis, 2 km from Medical District
9.0 out of 10, Wonderful, (2,008 reviews)
"Location is great, food is good, and rooms are nice and very clean."
United States
Rafael
The price is ￥21,425
￥25,763 total
includes taxes & fees
Nov 21 - Nov 22
Hyatt Centric Beale Street Memphis
A spacious interior with a grand piano, wooden furniture, and a stone fireplace.

13. Big Cypress Lodge

Big Cypress Lodge
5.0 star property
Pinch District, 2.4 km from Medical District
9.2 out of 10, Wonderful, (1,836 reviews)
"Absolutely love staying here, beautiful space, always warm and inviting."
United States
Dana
The price is ￥35,975
￥46,239 total
includes taxes & fees
Dec 6 - Dec 7
Big Cypress Lodge
A modern bar area with a central island, bar stools, pendant lighting, and a view of the city through large windows.

14. Canopy by Hilton Memphis Downtown

Canopy by Hilton Memphis Downtown
4.0 star property
Downtown Memphis, 1.6 km from Medical District
8.6 out of 10, Excellent, (1,000 reviews)
"The staff at this hotel made it feel like home. The kindness from all of the staff was amazing. The hospitality and knowledge was refreshing."
United States
Marie
The price is ￥20,172
￥24,273 total
includes taxes & fees
Nov 26 - Nov 27
Canopy by Hilton Memphis Downtown
A modern lobby with a sofa set, chairs, and a coffee table.

15. The Westin Memphis Beale Street

The Westin Memphis Beale Street
4.0 star property
Downtown Memphis, 1.7 km from Medical District
8.8 out of 10, Excellent, (1,001 reviews)
"Great location- made walking to sites very easy"
United States
Jessica
The price is ￥22,847
￥27,450 total
includes taxes & fees
Nov 26 - Nov 27
The Westin Memphis Beale Street
A multi-story hotel with a modern design, featuring a prominent logo at the top.

16. Aloft by Marriott Memphis Downtown

Aloft by Marriott Memphis Downtown
3.0 star property
Downtown Memphis, 1.6 km from Medical District
9.0 out of 10, Wonderful, (326 reviews)
"Great place to stay."
United States
LISA
The price is ￥18,877
￥22,737 total
includes taxes & fees
Dec 14 - Dec 15
Aloft by Marriott Memphis Downtown
A spacious lobby with a curved carpet, seating areas, a staircase, and a reception desk.

17. Courtyard by Marriott Downtown Memphis

Courtyard by Marriott Downtown Memphis
3.0 star property
Downtown Memphis, 1.9 km from Medical District
8.6 out of 10, Excellent, (1,000 reviews)
"Great stay!"
United States
Christian
The price is ￥21,425
￥25,762 total
includes taxes & fees
Nov 24 - Nov 25
Courtyard by Marriott Downtown Memphis
A spacious lounge area with multiple seating options, a bar, and a staircase leading to an upper level.

18. The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton
4.0 star property
South Main, 2.4 km from Medical District
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay!"
United States
Stephen
The price is ￥19,521
￥23,502 total
includes taxes & fees
Nov 24 - Nov 25
The Central Station Memphis, Curio Collection by Hilton
A modern living room with a glass dining table, grey sofas, and a large TV.

19. The Stallion

The Stallion
4.5 star property
Downtown Memphis, 2.4 km from Medical District
9.8 out of 10, Exceptional, (493 reviews)
"Always a wonderful experience here."
United States
Darryl
The price is ￥17,314
￥31,754 total
includes taxes & fees
Dec 14 - Dec 15
The Stallion
A cozy lounge area with a large window, comfortable seating, and a coffee table with books.

20. ARRIVE Memphis, a Member of Design Hotels

ARRIVE Memphis, a Member of Design Hotels
4.0 star property
South Main, 2.3 km from Medical District
9.6 out of 10, Exceptional, (1,070 reviews)
"The rooms and the lobby are exceptional. The staff is very friendly and welcoming."
United States
Christine
The price is ￥23,966
￥28,779 total
includes taxes & fees
Nov 24 - Nov 25
ARRIVE Memphis, a Member of Design Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Medical District

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A hotel room with two beds, each with a patterned bedspread, a nightstand with a lamp, and a wall-mounted light fixture.
Motel 6 Memphis, TN - Downtown
2.0 star property
5.4
1,005 reviews
View
A modern hotel with "La Quinta" signage, featuring a prominent entrance and a covered walkway.
La Quinta Inn & Suites by Wyndham Memphis Downtown
3.0 star property
9.2
Wonderful
1,352 reviews
View
A multi-story parking garage with a Comfort Inn sign, surrounded by high-rise buildings.
Comfort Inn Memphis Downtown
2.5 star property
8.8
Excellent
1,387 reviews
View
A hotel reception area with a counter, a fruit display, and a seating area with chairs.
Holiday Inn Express Memphis Medical Center Midtown by IHG
2.5 star property
8.4
Very good
1,007 reviews
View
A modern living room with a glass dining table, grey sofas, and a large TV.
The Stallion
4.5 star property
9.8
Exceptional
493 reviews
View

Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most.
A bustling street lined with neon signs and a crowd of people walking.

Downtown Memphis

Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.

A bridge with blue lights at dusk.

East Memphis

East Memphis is beloved for its popular shops. Take some time to explore sights in the area like Leftwich Tennis Center and Theatre Memphis.

A neon-lit street with signs for restaurants and clubs.

Midtown

Immerse yourself in the arts scene with institutions like Playhouse on the Square and Brooks Museum of Art, or explore Overton Park's Memphis Zoo. Enjoy live music at Cooper-Young's vibrant bars and restaurants, and easily navigate via bike lanes and trolley lines.

A garden with a plaque about Graceland, a historic site built in 1939.

Whitehaven

Graceland mansion, a major tourist attraction, and the renovated David Carnes Park await visitors in this South Memphis neighborhood. Do some shopping at Southland Mall or explore along Elvis Presley Boulevard.

A cityscape with a prominent bridge, a river, and a large building with a unique architectural design.

Southwind

Travelers come to Southwind for its abundant dining options, and you can see top attractions like Mike Rose Soccer Complex and TPC Southwind while you're in town.

Top Medical District Hotel Reviews

A modern hotel with "La Quinta" signage, featuring a prominent entrance and a covered walkway.
La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Downtown
Downtown Memphis

10/10 Excellent

The location was great. Easy, safe parking!
United States
Amanda
Reviewed June 29, 2025
La Quinta Inn & Suites by Wyndham Memphis Downtown

Frequently Asked Questions

What's it like in Medical District?

Travelers will be sure to enjoy their time in Memphis's Medical District neighborhood. Are you looking for Medical District travel tips? Be sure to check out Sun Studio and NAACP Memphis while you're in the neighborhood.

What's the best accommodation in Medical District?

Based on our traveler data, Kings Inn is one of the top choices for your stay in Medical District. This hotel offers free parking and free WiFi. Another good option for your stay in the neighborhood is Motel 6 Memphis, TN - Downtown.

How many hotels will I find in Medical District?

When you want to kick up your feet after a day of exploring the sights in Memphis, you can choose from 18 Expedia hotels and other accommodations in Medical District.

If I need to cancel my hotel reservation in Medical District, will I receive a refund?

Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals in Medical District.

Where can I learn more about changing or cancelling my trip to Medical District?

To find more details about updating your trip to Medical District or cancelling it, click here.

What are the top things to see and do in Medical District?

Some landmarks in Medical District that you won't want to miss include Sun Studio, NAACP Memphis, and Hunt-Phelan Home. Woodruff-Fontaine House and Mallory-Neely House are also worth a visit when you're out sightseeing in Memphis.