A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

Find hotels near Mcleod Regional Medical Center, Florence from ￥7,739

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 3 - Oct 4
Tomorrow
Oct 4 - Oct 5
Next weekend
Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18

Filter by

Property class

Guest rating

Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A modern lounge area with brick walls, large windows, and contemporary furniture.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.7 km from Mcleod Regional Medical Center
United States
Ivette
￥15,785
￥17,680 total
includes taxes & fees
Oct 12 - Oct 13
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.
An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.8 km from Mcleod Regional Medical Center
United States
Ankh
￥19,095
￥21,387 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
1.2 km from Mcleod Regional Medical Center
United States
F
￥6,709
￥7,739 total
includes taxes & fees
Nov 2 - Nov 3
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.
A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.
A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.

4. The Urban Flats

The Urban Flats
0.8 km from Mcleod Regional Medical Center
￥40,179
￥68,678 total
includes taxes & fees
Oct 7 - Oct 8
The Urban Flats
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.
A breakfast setup with a flat-screen TV displaying a breakfast menu, a flat-screen TV, a coffee machine, and a tray of pancakes.
A hotel pool area with two pools, a lifeguard stand, and a towel service station.

5. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
8 km from Mcleod Regional Medical Center
United States
Leigh
￥16,890
￥18,918 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

6. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
5.5 km from Mcleod Regional Medical Center
United States
Windia
￥14,096
￥15,786 total
includes taxes & fees
Oct 11 - Oct 12
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
7 km from Mcleod Regional Medical Center
United States
Mila
￥15,967
￥17,883 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Inn & Suites Florence Center Area
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.
A corridor with shelves stocked with snacks and a frozen food display.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

8. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
5.7 km from Mcleod Regional Medical Center
United States
Ashokraju
￥19,321
￥21,638 total
includes taxes & fees
Oct 7 - Oct 8
Hampton Inn & Suites Florence-North-I-95
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A two-story building with a brick facade, a flat roof, and a covered entrance area.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

9. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
5.5 km from Mcleod Regional Medical Center
United States
HOMERO
￥10,197
￥11,420 total
includes taxes & fees
Oct 5 - Oct 6
Howard Johnson by Wyndham Florence
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.
An outdoor kitchen area with a grill, a pool, and a covered seating area.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

10. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
8.1 km from Mcleod Regional Medical Center
United States
Tishia
￥21,310
￥23,867 total
includes taxes & fees
Nov 1 - Nov 2
Staybridge Suites Florence - Civic Center by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
6.9 km from Mcleod Regional Medical Center
United States
Felecia
￥18,650
￥20,888 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott Florence I-20
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A modern lounge area with a sofa, armchairs, and small tables.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
7 km from Mcleod Regional Medical Center
United States
Crystal
￥17,979
￥20,136 total
includes taxes & fees
Nov 1 - Nov 2
TownePlace Suites by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern lounge area with seating, tables, and a pool table.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Tiffany
￥15,967
￥18,823 total
includes taxes & fees
Oct 11 - Oct 12
Tru by Hilton Florence I-95
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.
A hotel with a modern design, featuring multiple floors and a parking lot.
A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

14. Residence Inn Marriott Florence

Residence Inn Marriott Florence
7.2 km from Mcleod Regional Medical Center
United States
TERRENCE
￥17,553
￥19,658 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn Marriott Florence
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
A breakfast buffet with a variety of food items, including pastries and cereal boxes, and a sign indicating the availability of cinnamon sweet rolls.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

15. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
9.1 km from Mcleod Regional Medical Center
United States
Christopher
￥18,784
￥22,602 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

16. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
5.5 km from Mcleod Regional Medical Center
United States
Tienia
￥13,283
￥15,499 total
includes taxes & fees
Oct 18 - Oct 19
Spark by Hilton Florence North I-95, SC
A spacious lobby with a reception desk, seating area, and large windows.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

17. Hilton Garden Inn Florence

Hilton Garden Inn Florence
7.2 km from Mcleod Regional Medical Center
United States
Derrick
￥18,650
￥20,887 total
includes taxes & fees
Oct 11 - Oct 12
Hilton Garden Inn Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.
A hotel lobby with a reception desk, seating area, and a welcome mat.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
7.2 km from Mcleod Regional Medical Center
United States
Ryan
￥17,979
￥20,136 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites Florence Center
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

19. Comfort Suites Florence I-95

Comfort Suites Florence I-95
5.9 km from Mcleod Regional Medical Center
United States
Denise
￥13,392
￥15,630 total
includes taxes & fees
Oct 25 - Oct 26
Comfort Suites Florence I-95
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with lounge chairs and a building with balconies.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

20. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
7.5 km from Mcleod Regional Medical Center
Canada
Noémie
￥13,922
￥15,592 total
includes taxes & fees
Oct 18 - Oct 19
Quality Inn & Suites Florence Civic Center
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"Edward was amazing helping straighten out an issue with my Expedia booking"
Cynthia 1-night trip
Posted 6 hours ago
Spark by Hilton Florence North I-95, SC
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

8/10 Good
"The room was clean and it was a peaceful and quiet night of sleep. I appreciated the comfy bed and pillows. The air took awhile to actually cool the room off but it got cold after awhile (1+ hours). The breakfast was disappointing as the non-bread options were not replenished. I understand this at 9:55am. Not at 9.20am. The staff seemed annoyed to answer questions about the lack of breakfast food options or if they were being replenished."
Leah 1-night trip
Posted 1 day ago
Park Inn by Radisson Florence, SC
Best Western Inn

Best Western Inn

10/10 Excellent
"Clean rooms and friendly staff and great breakfast"
Steward Heikes 1-night trip
Posted 7 days ago
Best Western Inn
Pineapple House: Historic. Southern Charm. Walk Downtown.

Pineapple House: Historic. Southern Charm. Walk Downtown.

10/10 Excellent
"Absolutely beautiful home in a quiet, safe neighborhood. It had everything I needed for an incredible stay. Excellent water pressure in shower. Comfortable bed, beautiful decor, snacks, water, and communication with owner was excellent. Easy check in and check out. Thank you for your hospitality and for being so welcoming during my stay. This is THE place to stay in Florence, SC. Thank you again. I will return in the future."
Leanna F. 3-night trip
Posted 3 weeks ago
Pineapple House: Historic. Southern Charm. Walk Downtown.
Come Stay A While

Come Stay A While

10/10 Excellent
"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."
Anndria C. 14-night trip
Posted 3 months ago
Come Stay A While

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, check out the 18 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels will I find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodations within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals near Mcleod Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Mcleod Regional Medical Center?
For more information about updating your stay near Mcleod Regional Medical Center or cancelling it, click here.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.