The Best Hotels Closest to Mayo Civic Center in Rochester for 2026

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Our top choices for Mayo Civic Center hotels

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 2.3 km from Mayo Civic Center

Brien

￥19,057

￥21,939 total

includes taxes & fees

Nov 6 - Nov 7

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

A modern interior with a large dining table, sofas, and a kitchen area.

2. The Berkman

Folwell, 2 km from Mayo Civic Center

Suzette

￥32,122

￥37,351 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern lounge area with a sofa, chairs, and tables.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern hotel room with a bed, desk, and kitchenette.

3. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.9 km from Mayo Civic Center

howard

￥18,728

￥21,561 total

includes taxes & fees

Nov 12 - Nov 13

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern lounge area with seating, a fireplace, and a bar area.

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.7 km from Mayo Civic Center

Chee

￥20,923

￥24,089 total

includes taxes & fees

Nov 13 - Nov 14

A coffee shop interior with a wooden counter, menu boards, and seating area.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel room with a bed, bedside table, and a window with curtains.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 0.9 km from Mayo Civic Center

Cory

￥21,649

￥24,924 total

includes taxes & fees

Nov 6 - Nov 7

A modern indoor patio with a fire feature, seating, and large windows.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1.5 km from Mayo Civic Center

James

￥18,014

￥22,873 total

includes taxes & fees

Oct 23 - Oct 24

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1.5 km from Mayo Civic Center

Amanda

￥18,070

￥21,120 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel room with a large round table, two sofas, a TV, and a bed.

A reception area with a clock, a counter, and a nameplate.

A person at a checkout counter in a store, with various snack items and a sign indicating a price of $1.50.

8. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.7 km from Mayo Civic Center

Kevin

￥19,120

￥22,012 total

includes taxes & fees

Nov 4 - Nov 5

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

9. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 0.2 km from Mayo Civic Center

Jennifer

￥26,729

￥30,771 total

includes taxes & fees

Nov 7 - Nov 8

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A conference room with a long table, multiple chairs, and decorative wall art.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 1.9 km from Mayo Civic Center

MATTHEW

￥17,864

￥20,566 total

includes taxes & fees

Nov 6 - Nov 7

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A gym with exercise equipment, a clock, and a window with blinds.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 1.9 km from Mayo Civic Center

Lin

￥18,670

￥21,494 total

includes taxes & fees

Nov 6 - Nov 7

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

A compact laundry area with a washing machine, dryer, and a water fountain.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

12. Econo Lodge Mayo Clinic Area

3.2 km from Mayo Civic Center

Ashley

￥10,584

￥12,185 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern indoor pool area with lounge chairs and a pool.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

13. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 0.6 km from Mayo Civic Center

Elsie

￥20,069

￥23,105 total

includes taxes & fees

Nov 6 - Nov 7

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

14. Hampton Inn Rochester-South

3 km from Mayo Civic Center

dennis

￥17,327

￥19,948 total

includes taxes & fees

Nov 6 - Nov 7

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A hotel room with a kitchenette, a dining area with striped chairs, a sofa, a TV, and a window with curtains.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

15. Aspen Suites

1.7 km from Mayo Civic Center

Douangta

￥20,955

￥25,331 total

includes taxes & fees

Oct 29 - Oct 30

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

An outdoor dining area with wooden beams, tables, and chairs.

A reception desk with a modern design, featuring a wooden panel and a wall adorned with framed botanical artwork.

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 0.3 km from Mayo Civic Center

Hernan

￥16,908

￥19,467 total

includes taxes & fees

Oct 23 - Oct 24

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

17. Brentwood Inn & Suites

Downtown Rochester, 0.7 km from Mayo Civic Center

Elaine

￥19,753

￥22,741 total

includes taxes & fees

Nov 5 - Nov 6

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

18. Quality Inn & Suites Mayo Clinic Area

2.7 km from Mayo Civic Center

Jessica

￥10,671

￥12,456 total

includes taxes & fees

Nov 13 - Nov 14

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

19. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 0.3 km from Mayo Civic Center

Richard

￥18,670

￥21,494 total

includes taxes & fees

Nov 7 - Nov 8

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1 km from Mayo Civic Center

Christine

￥18,046

￥20,775 total

includes taxes & fees

Oct 23 - Oct 24

View all properties

Compare popular hotels close to Mayo Civic Center

Property	Star rating	Guest rating
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 748 reviews	View
The Berkman	9.6 Exceptional 449 reviews	View
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,003 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 316 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 569 reviews	View

Hotels recommended for families near Mayo Civic Center

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

￥16,908

￥19,467 total

includes taxes & fees

Oct 23 - Oct 24

Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

￥20,069

￥23,105 total

includes taxes & fees

Nov 6 - Nov 7

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

A bar area with a long counter, multiple bar stools, and a television mounted above the bar.

A banquet hall with round tables, chairs, chandeliers, and a fireplace.

A hotel room with a large bed, a desk, a chair, a microwave, and a framed picture on the wall.

Kahler Grand Hotel

Downtown Rochester

￥22,361

￥25,742 total

includes taxes & fees

Oct 23 - Oct 24

A hotel room with a large bed, a desk with a chair, a television, and a window with a city view.

A modern indoor swimming pool with clear water, surrounded by lounge chairs and a seating area with a patterned wall.

A hotel room with a large bed, a sofa, a desk with a TV, and a view of the city.

A modern hotel room with a large window, a sofa set, a dining table, and a lamp.

Hilton Rochester Mayo Clinic Area

Downtown Rochester

￥28,072

￥32,318 total

includes taxes & fees

Nov 7 - Nov 8

Brentwood Inn & Suites

Downtown Rochester

￥19,753

￥22,741 total

includes taxes & fees

Nov 5 - Nov 6

Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester

￥26,729

￥30,771 total

includes taxes & fees

Nov 7 - Nov 8

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

A restaurant with a bar area, wooden chairs, and a stone wall.

A modern building with large windows and a parking lot.

A reception area with a wooden reception desk, a clock, and a wall-mounted display.

Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester

￥19,894

￥22,904 total

includes taxes & fees

Oct 31 - Nov 1

Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester

￥18,670

￥21,494 total

includes taxes & fees

Nov 7 - Nov 8

Top Mayo Civic Center Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"It was a great experience"

Broadway Plaza, Trademark Collection by Wyndham

10/10 Excellent

"The property had two bathrooms which was a nice surprise. The kitchen had a full size refrigerator, dishwasher, and laundry machine. The room also had a very pleasant air freshener smell and the bathroom had night lights so you didn'thave to turn on the bathroom's big light in during the night. Thank you for making our stay so pleasant."