Los Anastacios Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jan 7 - Jan 8
Tomorrow
Jan 8 - Jan 9
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Our top choices for Los Anastacios vacation rentals

Honeymoon Cabin, 1 King Bed, Valley View, Mountainside | Living area | 100-cm flat-screen TV with digital channels, TV, Netflix
Villa Alejandro

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (131)
"Very clean room and very quiet. WiFi is great and I really enjoyed having free parking right beside the building. The staff made sure I checked in ok as there was self check in."
United States
Rico
Villa Alejandro
Front of property
Aires frescos de Boquete

Aires frescos de Boquete

Aires frescos de Boquete
2.0 star property
Alto Boquete
9.0 out of 10, Wonderful, (4)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is ￥8,072
￥8,879 total
includes taxes & fees
Jan 11 - Jan 12
Aires frescos de Boquete
Premier Suite, 1 King Bed, Garden View | Premium bedding, down comforters, individually decorated
El Cielo by Villa Alejandro

El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (93)
"We stayed here for a week while in Boquete and already plan to stay here when we return in a few months. The accomodation was clean with a well-stocked kitchen. The location is perfect to walk around the wonderful shops and restaurants in Boquete. The management team was very responsive to questions, ect. The accomodation is bright and airy and is perfect for short and long-term stays. We cannot recommend El Cielo enough!"
United States
Susan
El Cielo by Villa Alejandro
Tree House | Terrace/patio
Cabanas Rio Encantado

Cabanas Rio Encantado

Cabanas Rio Encantado
3.0 star property
Caldera
9.4 out of 10, Exceptional, (40)
"This was our favorite place. Clean, gorgeous grounds, comfortable rooms, killer pool, riverside, very accommodating host. Love, love, love."
United States
Kristin
The price is ￥16,018
￥17,620 total
includes taxes & fees
Jan 13 - Jan 14
Cabanas Rio Encantado
Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub
Casa Reina by Villa Alejandro

Casa Reina by Villa Alejandro

Casa Reina by Villa Alejandro
3.5 star property
Boquete
8.4 out of 10, Very Good, (15)
"The property is outside of the town proper, so is quiet and it is possible to see wildlife. The room was extremely clean and comfortable, and the staff was welcoming and friendly. The view from the balcony was amazing!"
Canada
Catherine
The price is ￥14,095
￥18,480 total
includes taxes & fees
Jan 13 - Jan 14
Casa Reina by Villa Alejandro
Tree House, Mountain View | View from room
Lucero - Luxury Treehouses

Lucero - Luxury Treehouses

Lucero - Luxury Treehouses
3.5 star property
Jaramillo
8.6 out of 10, Excellent, (4)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
The price is ￥52,679
￥57,947 total
includes taxes & fees
Jan 11 - Jan 12
Lucero - Luxury Treehouses
Family Apartment, 2 Bedrooms | Living area | 50-inch Smart TV with digital channels
Peace N' Green

Peace N' Green

Peace N' Green
3.0 star property
David
The price is ￥7,421
￥8,163 total
includes taxes & fees
Jan 12 - Jan 13
Peace N' Green
Condo, 2 Bedrooms | 2 bedrooms, iron/ironing board, free WiFi
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.0 star property
El Tropezón
The price is ￥20,663
￥39,328 total
includes taxes & fees
Jan 11 - Jan 12
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
Garden
Aparthotel Los Pinos

Aparthotel Los Pinos

Aparthotel Los Pinos
2.5 star property
Boquete
8.4 out of 10, Very Good, (16)
"The place was spacious, clean and comfortable. Great location and easy parking."
United States
Rebecca
The price is ￥17,619
￥19,381 total
includes taxes & fees
Jan 13 - Jan 14
Aparthotel Los Pinos
1 bedroom, Egyptian cotton sheets, pillowtop beds, free WiFi
Downtown Suites

Downtown Suites

Downtown Suites
3.0 star property
El Tropezón
9.0 out of 10, Wonderful, (101)
"Good location, nice rooms, great value."
United States
Robert
Downtown Suites
Exterior
Linda Vista Cabins

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is ￥7,846
￥8,631 total
includes taxes & fees
Feb 1 - Feb 2
Linda Vista Cabins
Family House, 2 Bedrooms, Garden View | 3 bedrooms, minibar, desk, free WiFi
Casa Little Italy

Casa Little Italy

Casa Little Italy
3.0 star property
Tijeras
6.0 out of 10, (1)
"Didn't accept credit card payment "
Mexico
ANGELO
The price is ￥12,529
￥13,782 total
includes taxes & fees
Jan 11 - Jan 12
Casa Little Italy
Deluxe Studio Suite, 1 King Bed, Non Smoking, Mountain View | Premium bedding, down comforters, individually decorated
Casa Mate by Villa Alejandro

Casa Mate by Villa Alejandro

Casa Mate by Villa Alejandro
3.5 star property
Los Naranjos
2.0 out of 10, (1)
The price is ￥13,954
￥18,325 total
includes taxes & fees
Jan 20 - Jan 21
Casa Mate by Villa Alejandro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Los Anastacios Hotel Reviews

Hampton by Hilton David

Hampton by Hilton David

10/10 Excellent
"The breakfast was very delicious and the server had the best smile ,was very friendly. Room and bed was fresh and clean. Would stay here again. "
Pamela 1-night trip
Posted 5 days ago
Hampton by Hilton David

Find out more about Los Anastacios

Search for holiday rentals in Los Anastacios on Expedia! You can easily find your home rentals, villas, holiday apartments in Los Anastacios using one of the methods below:

  • View our selection of featured holiday rentals in Los Anastacios
  • Use the map to find apartments and other holiday homes in the Los Anastacios neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Los Anastacios while they last

Look no further and take a look at our great range of rental properties in Los Anastacios!

Frequently asked questions

Can I find a vacation rental in Los Anastacios?

Yes, we offer vacation rentals close to popular points of interest in Los Anastacios, or you can go with a more remote option if you're looking for relaxation.

What are some of the best vacation rentals in Los Anastacios?

House in Boquete with king beds and hot tub: Visitors like this Los Anastacios vacation home rental. It is located in the mountains and has a balcony, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the hot tub in this rental home to help you unwind.

What’s there to see and do in Los Anastacios?

While you're exploring the area, Parque de las Madres and Miguel de Cervantes Saavedra Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Plaza El Terronal and Boquete Library.

What are vacation rentals like in Los Anastacios?

Vacation rentals are privately owned properties you can book for a few days or a quick weekend in Los Anastacios. Vacation rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family gatherings.