The Best Hotels Closest to Key West National Wildlife Refuge in Key West for 2026

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Our top choices for Key West National Wildlife Refuge hotels

A bottle of Marc's Reserve 12 FL. OZ. on a coaster with a metal table.

A patio area with white metal tables and chairs, surrounded by potted plants and palm trees.

A pool with a lion head sculpture in the center.

A potted yellow orchid plant in a garden setting with a brick pathway, palm trees, and a white building in the background.

1. Artist House Key West

Historic Seaport, 11.4 km from Key West National Wildlife Refuge

NATHAN

￥15,977

￥17,974 total

includes taxes & fees

Oct 11 - Oct 12

A building with a white exterior, a large red awning, and a gated entrance.

A spacious kitchen with a dining area, large windows, and a view of the outdoors.

A pool area with lounge chairs and a lifebuoy.

A paved pathway lined with various plants and trees, leading to a building with a beige exterior.

2. Authors of Key West Guest House

The Meadows, 12.4 km from Key West National Wildlife Refuge

Avamarie

￥14,037

￥15,792 total

includes taxes & fees

Sep 29 - Sep 30

A balcony with wicker furniture, a view of the sea, and a spiral staircase.

A spacious lobby with a marble floor, leather sofas, and large potted plants.

A swimming pool with lounge chairs and palm trees, overlooking a sunset over the water.

A modern dining area with a glass table, four chairs, and a ceiling fan.

3. Beachside Resort & Residences

16.5 km from Key West National Wildlife Refuge

James

￥12,369

￥28,955 total

includes taxes & fees

Sep 28 - Sep 29

A dining table with plates of food, a drink, and a view of a pool and palm trees.

A hotel entrance with a palm tree-lined driveway, a vintage car, and a metal canopy structure.

A hotel room with a bed, a TV, a coffee table, a sofa, and a view of the ocean.

A person standing by a window overlooking a beach with palm trees and the ocean.

4. Margaritaville Beach House Key West

14.5 km from Key West National Wildlife Refuge

TRICIA LYNN

￥32,872

￥46,906 total

includes taxes & fees

Sep 28 - Sep 29

A wooden archway leading to a pool area surrounded by lush tropical vegetation.

A tall palm tree with a white building in the background.

A large, two-story building with a symmetrical facade, a central entrance with a double door, and a balcony on the upper floor.

A beach with palm trees, a sandy shore, and a calm sea under a clear sky.

5. Parrot Key Hotel & Villas

Northside Resort, 14.4 km from Key West National Wildlife Refuge

Anthony

￥19,977

￥31,499 total

includes taxes & fees

Sep 28 - Sep 29

A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

A covered outdoor area with a wooden staircase, seating, and potted plants.

A bedroom with a bed, nightstand, lamp, air conditioning unit, and a no smoking sign.

A two-story building with a porch, a sign reading "The Grand Guesthouse," and a purple flag.

6. The Grand Guesthouse

Old Town Key West, 12.5 km from Key West National Wildlife Refuge

Travis

￥17,743

￥23,892 total

includes taxes & fees

Sep 30 - Oct 1

A tropical outdoor area with palm trees, hanging plants, and string lights.

A large, two-story building with a balcony, surrounded by dense tropical foliage.

A hotel room with a bed, a wooden floor, a seating area with a table and chairs, and a view of greenery outside.

A wooden deck with lush greenery and a pool area.

7. Douglas House - Adults Only

Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge

michael

￥18,535

￥22,935 total

includes taxes & fees

Sep 28 - Sep 29

A room with a door featuring horizontal blinds, a visible outdoor view through the window, and a patterned carpet.

A garden with a stone pathway, a wooden fence, and various tropical plants.

A pool area with a covered seating area, palm trees, and a small pavilion.

A room with a bed, a desk, a chair, a lamp, a painting of a boat on water, and a view of the sea.

8. Alexander Palms Court

Casa Marina, 12.4 km from Key West National Wildlife Refuge

Andrew

￥18,756

￥21,101 total

includes taxes & fees

Sep 28 - Sep 29

A covered porch with wicker furniture, potted plants, and a sign for the "Office" at the Palm Hotel.

A pink building with a white door, a balcony with a white railing, and a view of a pool area.

A hotel with a white facade, multiple balconies, and lush tropical landscaping.

A row of bicycles parked in front of a building with a white balcony and a palm tree.

9. The Palms Hotel

The Meadows, 12.5 km from Key West National Wildlife Refuge

Zachary

￥21,101

￥27,278 total

includes taxes & fees

Sep 28 - Sep 29

A pool area with lounge chairs and a cabana.

A dining area with a glass table, clear glass bottles, a bowl of fruit, and a wicker chair.

A waterfront hotel with a long pier, multiple balconies, and a view of the ocean.

A balcony with a table set for breakfast, overlooking the sea.

10. Ocean Key Resort - A Noble House Resort

Historic Seaport, 11 km from Key West National Wildlife Refuge

Brian

￥30,552

￥46,581 total

includes taxes & fees

Sep 29 - Sep 30

A rectangular pool with a white deck, surrounded by lush greenery and a gazebo.

A wicker outdoor seating area with two chairs and a table, surrounded by lush tropical foliage.

A hotel room with a bed, a nightstand, a chair, a small table, and a ceiling fan.

A cozy living room with a wooden ceiling, a sofa set, two side tables with lamps, and framed artwork on the wall.

11. Ambrosia Key West

Old Town Key West, 11.6 km from Key West National Wildlife Refuge

Tricia

￥21,115

￥23,755 total

includes taxes & fees

Sep 28 - Sep 29

A bedroom with a four-poster bed, a wooden desk, wicker chairs, and a view of the outdoors.

A breakfast buffet with a variety of fruits, pastries, and beverages on a wooden deck with a view of a lush garden and a pool.

A cozy room with a wicker chair, a small table with a bottle and glasses, and a view of a yellow room through an open door.

A pool area with lounge chairs and candles, surrounded by palm trees and a building in the background.

12. Tropical Inn

Downtown Key West, 11.7 km from Key West National Wildlife Refuge

Molly

￥15,173

￥21,002 total

includes taxes & fees

Sep 28 - Sep 29

A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.

A swimming pool with lounge chairs, surrounded by palm trees and greenery.

A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.

A building with a sign reading "ALMOND Frog & Toad Inn" and a "VACANCY" sign below it.

13. Almond Tree Inn Hotel - Adults Only

Downtown Key West, 11.8 km from Key West National Wildlife Refuge

John

￥24,347

￥27,391 total

includes taxes & fees

Sep 30 - Oct 1

A spacious living room with a balcony, a ceiling fan, and a large window offering a view of the ocean.

A multi-story hotel with balconies and a well-lit entrance.

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean at dusk.

A modern kitchen with white cabinets and a built-in microwave. There is a dining area with a table set for two, a sofa, and a balcony with a view of the ocean.

14. The Laureate Key West

New Town, 15.8 km from Key West National Wildlife Refuge

Mailyn

￥25,008

￥32,559 total

includes taxes & fees

Sep 28 - Sep 29

A wooden boardwalk with a palm tree and lamp post, leading to a waterfront.

A pool area with lounge chairs, palm trees, and a building with a tiled roof.

A hotel room with a desk, two beds, a TV, a ceiling fan, and a balcony with curtains.

A modern restaurant with a wooden counter, seating area, and large windows.

15. Courtyard by Marriott Key West Waterfront

Northside Resort, 14.8 km from Key West National Wildlife Refuge

Everton

￥28,153

￥31,672 total

includes taxes & fees

Sep 28 - Sep 29

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

An outdoor patio area with tables and chairs, a bar area with a counter and bar stools, and a TV mounted on the wall.

A wooden outdoor dining table set with glassware, candles, and lanterns, surrounded by lush greenery.

A hotel room with a large bed, a wooden nightstand, a desk, a chair, and a window with curtains.

16. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

New Town, 16.5 km from Key West National Wildlife Refuge

Patricia

￥20,289

￥27,248 total

includes taxes & fees

Sep 28 - Sep 29

A wooden deck with a hammock, pool, and lounge chairs overlooking a tropical garden.

A covered walkway with a wooden ceiling, white railings, and a brick path.

A compact kitchen with wooden cabinets, a microwave, stove, and refrigerator. There is a dining area with a table and chairs, and a sofa.

A pool area with lounge chairs and a wooden building with balconies.

17. Island City House Hotel

Historic Seaport, 11.7 km from Key West National Wildlife Refuge

Osvaldo

￥24,182

￥27,204 total

includes taxes & fees

Sep 28 - Sep 29

A room with a bed, a ceiling fan, and a window with blinds.

A cozy outdoor seating area with a wooden bench and a table, surrounded by potted plants and a coffee and tea sign.

A spacious kitchen with wooden cabinets, a granite countertop, and a ceiling fan.

A poolside area with lounge chairs, a covered seating area, and a small pool.

18. The Mermaid & Alligator

Old Town Key West, 12.1 km from Key West National Wildlife Refuge

Brian

￥28,310

￥31,849 total

includes taxes & fees

Sep 28 - Sep 29

A garden pathway leading to a white gazebo with pink flowers, surrounded by lush greenery and a white fence.

A bar area with a counter, chairs, and a clock.

A bedroom with a large bed, a television on a dresser, and a view of the outdoors through a sliding door.

A couple walking along a poolside pathway surrounded by lush greenery.

19. The Gardens Hotel

Downtown Key West, 11.6 km from Key West National Wildlife Refuge

Forrest

￥44,087

￥49,598 total

includes taxes & fees

Sep 29 - Sep 30

A swimming pool with water splashing, surrounded by palm trees and a building in the background.

A hotel with a pool, bicycles, and lush greenery.

A two-story yellow house with a porch, white railings, and green shutters.

The exterior of the Silver Palms Inn with a two-story structure, a green awning over the entrance, and a palm tree to the right.

20. Silver Palms Inn & Historic Homes

Old Town Key West, 12.2 km from Key West National Wildlife Refuge

sam

￥12,598

￥24,790 total

includes taxes & fees

Sep 28 - Sep 29

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Compare popular hotels close to Key West National Wildlife Refuge

Property	Star rating	Guest rating
Artist House Key West	9.8 Exceptional 456 reviews	View
Authors of Key West Guest House	9.2 Wonderful 1,061 reviews	View
Beachside Resort & Residences	8.6 Excellent 2,557 reviews	View
Margaritaville Beach House Key West	8.8 Excellent 1,802 reviews	View
Parrot Key Hotel & Villas	9.0 Wonderful 1,462 reviews	View

Top Key West National Wildlife Refuge Hotel Reviews

Southernmost Beach Resort and Guesthouses

8/10 Good

"Nice place, but over priced"

La Concha Key West, Autograph Collection

10/10 Excellent

"Great location"

The Marker Key West Harbor Resort

10/10 Excellent

"Always solid"

Douglas House - Adults Only

10/10 Excellent

"Everything about Douglas‘s house was exceptional. Especially the staff. We stayed well over a week and it was so worth it top-notch. Cannot wait to go back. Who was beautiful and well kept little kitchenette for coffee in our room. And the refrigerator just perfect."

Tranquility Guest House

8/10 Good

"I was completely unaware that this is a not your usual guest house that has a lobby or check-in. There is not one. I wanted to check my bags early, but that was a chore. All of the gates are locked with keypads, and I don't have the combination. Finally I see a cleaning lady, and despite a language barrier, we figure things out and I she tells me to gate entry codes as well as the code to pickup my luggage from the cleaning closet. Finally, I was text messaged all of the information for my room and the door codes, etc. Pretty much, room service, towels, and amenities are upon request, and they send you test messages asking if you need anything. It was an interesting stay in that regard. And I checked out by text message too."

Duval House

10/10 Excellent

"Fly in, Uber to and from the Duvall, fly home! Great place to have a fun time!"

Winslow's Bungalows - Key West Historic Inns

10/10 Excellent

"From before we arrived we already knew we chose the right place to stay! We had questions about parking our motorcycle on property and there was no hesitation to share information and also connect with us. The staff is great. We are recommending this location and properties to friends and family. Next time we’re in town, 100% this will be the place we stay. Location is great and the property is fun to explore. Thank you all for making our stay memorable!"

Hyatt Vacation Club at Sunset Harbor, Key West

10/10 Excellent

"Staff: friendly, attentive and professional. Location : excellent. Cleanliness: impeccable, very clean, Overall experience: exceptional, wonderful, highly recommended."

Ocean Key Resort & Spa

10/10 Excellent

"This resort was amazing! The best area and most beautiful in Old Town. Craig and the whole staff were lovely! Would def return!"

Other attractions near Key West National Wildlife Refuge

A wooden signpost with directional arrows pointing to various cities and their distances.

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.

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A coastal fortification with a staircase leading to a higher platform, overlooking the sea.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)

The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.

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Mallory Square

9.2/10 (15,939 reviews)

Arrive at this square at day’s end to find street performers, food carts and one of the most beautiful sunsets in the United States.

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A historic building with a tall tower, palm trees, and a vintage trolley.

Key West Shipwreck Museum

8.6/10 (361 reviews)

This interactive museum is home to unbelievable relics pulled from the bottom of the sea and a watchtower with views across the Gulf of Mexico.

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Coffee Butler Amphitheater

You can enjoy a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its entertainment choices.

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USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West.

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Florida Keys National Marine Sanctuary

9.0/10 (112 reviews)

Enjoy a trip to Florida Keys National Marine Sanctuary and popular activities like boating in Key West. In the area, take in the lively festivals and beautiful sunsets.

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Waterfront Playhouse

8.4/10 (7 reviews)

You can enjoy a show at Waterfront Playhouse during your trip to Key West. Wander the seaside and beautiful beaches in the area.

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Frequently asked questions

What's the area like around Key West National Wildlife Refuge?

Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, biking, and lively festivals. Key West is home to 2616 hotels and other accommodations, so you can find something that's perfect for your stay.

What's the best place to stay close to Key West National Wildlife Refuge?

Pier House Resort & Spa is one of the top choices for your stay based on our traveler data, and this resort offers a full-service spa and a private beach. You'll find it 6.9 mi (11 km) from Key West National Wildlife Refuge. Other good options around the area include Hyatt Centric Key West Resort and Spa and Southernmost Beach Resort and Guesthouses.

If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available near Key West National Wildlife Refuge.

Where can I learn more about changing or cancelling my trip in the area near Key West National Wildlife Refuge?

For additional details about picking new dates or cancelling your stay near Key West National Wildlife Refuge, go to https://www.expedia.com/service/.

Find hotels near Key West National Wildlife Refuge, Key West from ￥15,792

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Treat yourself

Be picky

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Our top choices for Key West National Wildlife Refuge hotels

1. Artist House Key West

2. Authors of Key West Guest House

3. Beachside Resort & Residences

4. Margaritaville Beach House Key West

5. Parrot Key Hotel & Villas

6. The Grand Guesthouse

7. Douglas House - Adults Only

8. Alexander Palms Court

9. The Palms Hotel

10. Ocean Key Resort - A Noble House Resort

11. Ambrosia Key West

12. Tropical Inn

13. Almond Tree Inn Hotel - Adults Only

14. The Laureate Key West

15. Courtyard by Marriott Key West Waterfront

16. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

17. Island City House Hotel

18. The Mermaid & Alligator

19. The Gardens Hotel

20. Silver Palms Inn & Historic Homes

Compare popular hotels close to Key West National Wildlife Refuge

Top Key West National Wildlife Refuge Hotel Reviews

Southernmost Beach Resort and Guesthouses

La Concha Key West, Autograph Collection

The Marker Key West Harbor Resort

Douglas House - Adults Only

Tranquility Guest House

Duval House

Winslow's Bungalows - Key West Historic Inns

Hyatt Vacation Club at Sunset Harbor, Key West

Ocean Key Resort & Spa

Other attractions near Key West National Wildlife Refuge

Truman Beach

Fort Zachary Taylor Historic State Park

Mallory Square

Key West Shipwreck Museum

Coffee Butler Amphitheater

USCGC Ingham Maritime Museum

Florida Keys National Marine Sanctuary

Waterfront Playhouse

Frequently asked questions