Photo by Delen Wong

Find hotels in Isla Santa María from ¥7,124

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Our top choices for Isla Santa María hotels

PENGUIN HOSTEL

PENGUIN HOSTEL
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"Love the stay, very welcoming atmosphere, wonderful owners, I recommend this to everyone"
United States
LEO
The price is ¥3,848
¥7,795 total
Jan 12 - Jan 13
PENGUIN HOSTEL

ECO HOSTAL ISLA AZUL

ECO HOSTAL ISLA AZUL
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"Loved that they had purified water to refill your water bottle instead of buying plastic! Staff were incredibly kind. "
Canada
Jaclyn
The price is ¥21,703
¥28,334 total
Jan 12 - Jan 13
ECO HOSTAL ISLA AZUL

Ikala Galapagos Hotel

Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (129 reviews)
"Great staff—very helpful. Nice room and good location."
United States
Karen
Ikala Galapagos Hotel

El Barranco Galapagos

El Barranco Galapagos
2.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (35 reviews)
"Very comfortable hotel with good service and nice staff."
United States
jairo
The price is ¥28,013
¥28,013 total
Jan 20 - Jan 21
El Barranco Galapagos

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (122 reviews)
"Beautiful property "
Canada
David
The price is ¥36,115
¥39,726 total
Jan 14 - Jan 15
Blu Galapagos Sustainable Waterfront Lodge

Twin Hotel Galapagos

Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very Good, (44 reviews)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Canada
Chelsea
The price is ¥13,507
¥13,507 total
Jan 12 - Jan 13
Twin Hotel Galapagos

Hotel La Casa de Judy

Hotel La Casa de Judy
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (161 reviews)
"No view from the room, breakfast is so so"
United States
Wai Shan
The price is ¥13,689
¥16,057 total
Feb 11 - Feb 12
Hotel La Casa de Judy

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (14 reviews)
"Beautiful hotel, with amazing staff, and great location "
United States
Steven
The price is ¥30,552
¥33,607 total
Jan 12 - Jan 13
Hotel Santa Fe

Mainao

Mainao
3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (34 reviews)
"Great place to stay"
United States
Pavel
Mainao

Capitan Max B&B

Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (205 reviews)
"Clean , friendly staff, accommodating "
United States
Anna
The price is ¥12,495
¥12,495 total
Jan 15 - Jan 16
Capitan Max B&B

Grand Hotel Leon Marino Galapagos

Grand Hotel Leon Marino Galapagos
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (14 reviews)
"Staff was very friendly and location convenient. Modern interior."
United Kingdom
Marc
The price is ¥14,589
¥14,589 total
Jan 12 - Jan 13
Grand Hotel Leon Marino Galapagos

Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (106 reviews)
"Overall excellent choice for a family stay in Puerto Ayora. Rooms are very clean and spacious and short walk to main ferry pier and lots of restaurants and shopping. "
United States
Aaron
The price is ¥19,894
¥19,894 total
Jan 13 - Jan 14
Maidith Galapagos Inn

Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (92 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
United States
Jonathan
The price is ¥85,811
¥95,380 total
Feb 6 - Feb 7
Finch Bay Galapagos Hotel

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (270 reviews)
"Wonderful staff, beautiful room, delicious breakfast!"
United States
Ashley
The price is ¥34,736
¥38,210 total
Jan 13 - Jan 14
Hotel Cucuve

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (126 reviews)
"More 4 stars for the location, the rooms were ok, beds were extremely firm, we had an issue that was difficult to try and get resolved and never actually was resolved, food at their restaurant was great including the complementary breakfast, very nice that it’s five minutes from an amazing beach and 15 minutes from Las Grietas "
United States
Benjamin
The price is ¥38,517
¥42,369 total
Jan 13 - Jan 14
Angermeyer Waterfront Inn

Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very Good, (219 reviews)
"Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. "
Canada
Aly
Hotel Ninfa

Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (26 reviews)
"Staff very professional, respect of our privacy, clean and affordable."
Canada
Sean
The price is ¥23,447
¥23,447 total
Jan 27 - Jan 28
Fernandina Hotel & Spa Galápagos

Plaza Luna Suites

Plaza Luna Suites
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (36 reviews)
"The people were so great, helpful friendly family good vibes, came back a second time already and would stay here next time for sure :)"
Canada
Dustin
Plaza Luna Suites

Lava House Hostal

Lava House Hostal
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (53 reviews)
"I stayed here twice. Both times highly satisfactory. Staff was very friendly and accommodatding. The rooms and garden area are in excellent upkeep and pleasant to hang out in hammocks or seating arrangements. The owners are very kind people, who even helped me organize a free ride back to the airport upon my departure (a relative happened to also take a flight off the island). I highly recommend this establishment. "
United States
Irmgard
Lava House Hostal

Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel
2.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (25 reviews)
"We had a great stay at Acacia. The location was very central and walkable to shops, dinner, the Charles Darwin Center, and a couple of beaches. The rooms were spacious and spotlessly clean. And the staff was very friendly and helpful, plus a delicious fresh breakfast daily. So glad we planned a couple of days in Puerto Ayora - there are sea lions, tortoises, and marine iguanas all over the place and we spent a lovely day at Tortuga Bay (thanks to recommendation from Acacia staff). Wish we had...
United States
Chenoa
The price is ¥38,329
¥38,329 total
Jan 17 - Jan 18
Acacia Galapagos Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Isla Santa María attractions

Learn more about Isla Santa María

Head to sights like Galápagos National Park and Post Office Bay as you discover Isla Santa María.

The circle of life. A sea lion napping near a washed up whale skeleton. The best way to see the Galapagos is island hopping on a cruise ship.  #LifeAtExpedia
Photo by Delen Wong
Open Photo by Delen Wong

Top Isla Santa María Hotel Reviews

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Frequently asked questions

Where is the best place for a stay in Isla Santa María?
Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Hotel el descanso del Guia and Capitan Max B&B. See all available top hotels, or vacation rentals in Isla Santa María.
What are some of the best vacation rentals that Isla Santa María has to offer?
Villa Galapagos: This vacation home rental near Isla Santa María is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Isla Santa María.
If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.
Where can I learn more about changing or cancelling my trip to Isla Santa María?
For more details about updating your trip to Isla Santa María or cancelling it, click here.
What is staying in Isla Santa María like?
Travelers to Isla Santa María will find plenty to explore and enjoy. There are 209 hotels and other accommodations in larger region. Find out more about Isla Santa María.
What should I see while I'm in Isla Santa María?
Favorite places to visit include Galápagos National Park, Post Office Bay, and Punta Suarez. Check out what more to see and do in Expedia's Isla Santa María guide.
What's the weather like in Isla Santa María?
The hottest months are usually March and February with an average temp of 79°F, while the coldest months are September and October with an average of 72°F. Average annual precipitation for Isla Santa María is 13 inches.