Isla Santa María Vacations

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Photo by Delen Wong

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    Save up to ￥109,000 when you book a flight and hotel together*

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Find the Best Isla Santa María Vacation Packages

Isla Santa María Hotel Deals

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
The price is ￥22,821 per night from Nov 28 to Nov 29
￥22,821
￥22,821 total
Nov 28 - Nov 29
9/10 Wonderful! (452 reviews)
"Great place"

Reviewed on Oct 24, 2026

Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
The price is ￥18,370 per night from Oct 29 to Oct 30
￥18,370
￥18,370 total
Oct 29 - Oct 30
10/10 Exceptional! (172 reviews)
"I loved absolutely everything about the Maidith. The rooms are impeccable, the breakfast was delicious, the proprietors made us feel at home. He gave us great advice about tours, places to go and things to do. I wouldn't stay anywhere else in Puerto Ayora!"

Reviewed on Oct 26, 2026

Maidith Galapagos Inn
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos Puerto Ayora Galapagos
The price is ￥38,228 per night from Nov 21 to Nov 22
￥38,228
￥38,228 total
Nov 21 - Nov 22
El Barranco Galapagos
See all 217 properties in Isla Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin
Open Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties

What to do in Isla Santa María

Santa Fe Island & Playa Escondida Snorkeling Day Trip

Santa Fe Island & Playa Escondida Snorkeling Day Trip

￥28,082
per adult
Santa Fe Island & Playa Escondida Snorkeling Day Trip
Learn about the history of Floreana

Full Day Floreana Tour

￥34,514
per adult
Full Day Floreana Tour
Full Day Santa Fe and Playa escondida with Snorkeling and lunch Included

Day Trip Santa Fe and Playa escondida with Snorkeling

￥34,514
per adult
Day Trip Santa Fe and Playa escondida with Snorkeling
See all activities in Isla Santa María

Frequently asked questions

How much does an Isla Santa María vacation package cost?
You can grab a vacation package to this top destination on Expedia. However, how much your vacation to Isla Santa María costs will depend on factors like the season, length of stay and hotel choice.
What are the cheapest months to go to Isla Santa María?
You can usually find lower rates and better availability in January, April and June. Take a look at our cheap Isla Santa María vacation packages and you could score some great off-season discounts.
How many days is enough for Isla Santa María?
The ideal duration for your Isla Santa María vacation depends on what you'd like to do and see. Typically, a few days to a week will give you time to go to all the major sights and explore some hidden spots along the way.
How to find the best Isla Santa María package deals?
Start your search for an Isla Santa María package deal by entering your travel dates and destination under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Isla Santa María package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Isla Santa Marían escape underway.
Is it cheaper to book an Isla Santa María vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically land a better deal than booking each component individually. And you'll still get the flexibility to create a personalized Isla Santa María vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Isla Santa María?
If you have your Isla Santa María vacation dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Isla Santa María?

  1. Choose your dates: What you'd like to do in Isla Santa Marían and your preferred season will help you decide when to travel.
  2. Plan your budget wisely: As well as the price of your accommodations, you should factor in other expenses too. These include flights, food and transportation. Also, put aside some extra funds for unexpected expenses that may crop up during your trip to Isla Santa María.
  3. Decide how many days away: Start by making a list of all the activities and sights you want to get to in Isla Santa María. Then, estimate how long you'll need for each, including any travel time.
  4. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to choose an Isla Santa María vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.