Find hotels in South Central Houston, Houston from ￥8,883

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Discover 1,147 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for South Central Houston hotels

Hilton Houston Plaza/Medical Center
Sundeck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very Good, (1543)
"Always a nice stay"
The price is ￥14,210
￥16,797 total
includes taxes & fees
Sep 7 - Sep 8
Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG
Reception

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1002)
"Very friendly staff!"
The price is ￥21,171
￥27,730 total
includes taxes & fees
Sep 7 - Sep 8
InterContinental Houston by IHG
Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillowtop beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1764)
"Perfect location for me (Museum district) and great to have the hotel shuttle drop off service (within 3 mile radius)."
Hotel Zaza Houston Museum District
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very Good, (419)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is ￥20,016
￥23,419 total
includes taxes & fees
Sep 11 - Sep 12
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Houston Marriott Medical Center/Museum District
Lobby

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Enjoyed the stay"
The price is ￥22,518
￥30,881 total
includes taxes & fees
Sep 5 - Sep 6
Houston Marriott Medical Center/Museum District
The Westin Houston Medical Center/Museum District
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Lovely Hotel and Welcoming Staff, Great Restaurant and Comfy Quiet Room with a great shower. "
The price is ￥16,696
￥20,782 total
includes taxes & fees
Sep 5 - Sep 6
The Westin Houston Medical Center/Museum District
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (999)
"Cheap, quiet, clean, and friendly staff"
The price is ￥11,357
￥13,289 total
includes taxes & fees
Sep 5 - Sep 6
Americas Best Value Inn Medical Center Downtown
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1000)
"the place if very clean, beds are comfortable, A/C works great and quiet and the staff (Maria, Sasha) were great people. I would definitely recommend staying here again. "
The price is ￥12,024
￥14,110 total
includes taxes & fees
Sep 19 - Sep 20
Extended Stay America Suites Houston Med Ctr Braeswood Bl
La Maison in Midtown an urban B&B
Exterior

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (519)
"Nice property we are enjoying our stay. "
The price is ￥25,441
￥29,767 total
includes taxes & fees
Sep 16 - Sep 17
La Maison in Midtown an urban B&B
Wanderstay Houston Hostel
Interior

Wanderstay Houston Hostel

2.0 star property
8.4 out of 10, Very Good, (184)
"This is an amazing place to stay."
The price is ￥8,883
￥10,393 total
includes taxes & fees
Sep 6 - Sep 7
Wanderstay Houston Hostel
Hilton University of Houston
1 bedroom, premium bedding, down comforters, pillowtop beds

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (859)
"Perfect for new students and families."
The price is ￥23,784
￥27,828 total
includes taxes & fees
Sep 13 - Sep 14
Hilton University of Houston
Wanderstay Boutique Hotel
Double Room, 1 Queen Bed with Sofa bed | In-room safe, individually decorated, individually furnished, desk

Wanderstay Boutique Hotel

2.0 star property
10.0 out of 10, Exceptional, (41)
"Great stay!"
The price is ￥17,506
￥20,482 total
includes taxes & fees
Sep 15 - Sep 16
Wanderstay Boutique Hotel
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
The price is ￥30,646
￥38,077 total
includes taxes & fees
Sep 15 - Sep 16
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Rodeway Inn & Suites Houston near Medical Center
Fridge, microwave, stovetop, coffee/tea maker

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (487)
"Dirty"
Rodeway Inn & Suites Houston near Medical Center
Southmore Boulevard Motel
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (220)
"A classical Motel like in a Movie. The staff was really kind and helpful."
The price is ￥8,883
￥10,393 total
includes taxes & fees
Sep 11 - Sep 12
Southmore Boulevard Motel
Posh Dtwn Midtown Home w Stunning Roof-topterrace
House | 4 bedrooms, soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Modern Cozy Home with King Bed
Comfort Townhome | Private kitchen | Full-size fridge, microwave, oven, dishwasher

Modern Cozy Home with King Bed

3.5 star property
9.4 out of 10, Exceptional, (20)
"Very spacious and close to just about everything. The view is amazing too"
The price is ￥19,987
￥51,515 total
includes taxes & fees
Sep 10 - Sep 11
Modern Cozy Home with King Bed
Paradise Palace Best Rooftop in HTX w Hot Tub
House | 4 bedrooms, desk, iron/ironing board, Internet

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
The price is ￥45,832
￥95,718 total
includes taxes & fees
Sep 10 - Sep 11
Paradise Palace Best Rooftop in HTX w Hot Tub
The Oasis Checkmate HTX Rooftop
House | 4 bedrooms, desk, soundproofing, iron/ironing board

The Oasis Checkmate HTX Rooftop

3.0 star property
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
The price is ￥45,959
￥104,422 total
includes taxes & fees
Sep 10 - Sep 11
The Oasis Checkmate HTX Rooftop
The Green Haus Luxxe Cabana Rooftop Retreat
Apartment | 4 bedrooms, desk, Internet

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The Green Haus Luxxe Cabana Rooftop Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

2 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Houston featuring a city and a high rise building

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Top South Central Houston Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other favorite options in the area include The Westin Houston Medical Center/Museum District and MyCrib Houston Hostel.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1139 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Houston Zoo and Children's Museum of Houston are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.