A river with a bridge, a town, and a forested hillside.

Find Resorts & Hotels with Spas in Hannibal, MO

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Check availability on Hannibal Resorts & Hotels with Spas

This weekend
Jun 26 - Jun 28
Next weekend
Jul 3 - Jul 5

Our top choices for Hannibal hotels with a spa

Indoor pool, sun loungers

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (707 reviews)
  • cleanliness
    Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
The price is ￥13,986
￥16,617 total
includes taxes & fees
Jul 12 - Jul 13
Comfort Inn & Suites - Hannibal
Exterior

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
3.0 star property
Quincy
8.8 out of 10, Excellent, (655 reviews)
  • cleanliness
    Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
The price is ￥21,840
￥24,893 total
includes taxes & fees
Jul 3 - Jul 4
Holiday Inn Quincy East by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Hannibal

Pool
Breakfast included

Top Hannibal Hotel Reviews

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

10/10 Excellent
"Room was clean. Late arriving as 8pm. Got room an hour before. Spacious room! As others said tv was hard to figure out so we did not. Huge shower! Bed comfy Cold a/c just the way we like it. Buffet breakfast was hot! Tasty eggs, sausage, cubed potatoes. Had waffle option, yogurt, cereal, breads, bagels and mini muffins."
Kathy 1-night trip
Posted 5 hours ago
Quality Inn & Suites Hannibal West

Frequently asked questions

Looking to vacation at a spa hotel in Hannibal?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers recommend the gourmet restaurants in Hannibal. Enjoy the shopping and riverfront during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your vacation.
What is the best spa hotel in Hannibal?
Comfort Inn & Suites - Hannibal is a top spa hotel featuring a 24-hour fitness center and an indoor pool. Kick back and relax in the hot tub.
How many spa hotels are there in Hannibal?
Among Expedia's 55 accommodation options in Hannibal, there is 1 spa hotel.
What's there to see and do in Hannibal?
Take in the sights and attractions that Hannibal offers with a visit to Rockcliffe Mansion, Big River Train Town, and Mark Twain Boyhood Home and Museum. If you have a little extra time during your trip, you might want to check out Mark Twain Memorial Lighthouse and Lovers Leap.
What is a Hannibal spa hotel?
Spa hotels in Hannibal provide lodging and have an on-site spa offering services such as couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.