A densely packed urban area with numerous buildings and a prominent tower on a hill.

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Check prices for these dates

This weekend
Jul 17 - Jul 19
Next weekend
Jul 24 - Jul 26

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Our top choices for Puerto Santa Ana hotels

Rooftop terrace

1. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (57 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ￥11,186
￥13,134 total
Jul 19 - Jul 20
River View suites Puerto Santa Ana gye
2 bars/lounges, lobby lounge

2. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Nice river view, clean room, nice staff and breakfast buffet great!!!"
United States
Nancy
The price is ￥16,223
￥18,657 total
Aug 16 - Aug 17
Wyndham Guayaquil Puerto Santa Ana
Outdoor spa tub

3. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
The price is ￥13,872
￥14,196 total
Jul 24 - Jul 25
Luxury Suites Riverfront GYE
Property entrance

4. DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (643 reviews)
"Nice, clean simple, family run hotel with good transportation."
United States
Gerald
The price is ￥5,845
￥6,007 total
Jul 19 - Jul 20
DC Suites Aeropuerto
Terrace/patio

5. Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (273 reviews)
"Very clean and comfortable rooms. The staff was very friendly and they're all fluent in English and Spanish. Breakfast in the restaurant was also delicious."
United States
Myna-Maria
The price is ￥9,677
￥11,133 total
Jul 19 - Jul 20
Hotel Puerto Pacifico Guayaquil Airport
Terrace/patio

6. Villa Celeste - VC

Villa Celeste - VC
2.5 star property
4.9 km from Puerto Santa Ana
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
The price is ￥2,572
￥2,572 total
Jul 19 - Jul 20
Villa Celeste - VC
Comfort Villa, 3 Bedrooms | Living area

7. NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 0.8 km from Puerto Santa Ana
The price is ￥6,234
￥6,234 total
Jul 29 - Jul 30
NCG SUITE ATARAZANA
Deluxe House, 3 Bedrooms, Balcony | Iron/ironing board, WiFi (free)

8. NCG Suite 2

NCG Suite 2
2.0 star property
7.1 km from Puerto Santa Ana
The price is ￥3,937
￥3,937 total
Jul 26 - Jul 27
NCG Suite 2
Outdoor pool

9. Tropical Inn

Tropical Inn
2.0 star property
4.5 km from Puerto Santa Ana
8.0 out of 10, Very Good, (18 reviews)
"for the price was good"
United States
Rosa
The price is ￥3,799
￥6,234 total
Jul 19 - Jul 20
Tropical Inn
Superior Double Room | Private kitchen | Microwave, electric kettle, griddle, cookware/dishes/utensils

10. Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 3.5 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (15 reviews)
"Close to the airport, a little hard to find for taxi or delivery directions but turned out ok. Rooms were clean and had a fridge, range, microwave .. good for a few days to rest and be close to the airport"
United States
Manish
The price is ￥4,395
￥5,695 total
Aug 9 - Aug 10
Suitesecu Rentals Guayaquil
Double Room, 1 Queen Bed, Private Bathroom, Ground Floor | Outdoor pool | Outdoor pool, sun loungers

11. MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
8.4 out of 10, Very Good, (174 reviews)
"Room was great and very clean. The staff is amazingly friendly and nice. This will be my go to hotel from now on ."
United States
Gary
The price is ￥7,357
￥7,681 total
Jul 19 - Jul 20
MundialCity Hotel Guayaquil
Deluxe Loft | Living area | 65-inch LCD TV with digital channels, Netflix, heated floors

12. PRAGA APARTMENTS

PRAGA APARTMENTS
4.0 star property
Urdesa, 3.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (21 reviews)
"The room was very nice and the employees were very friendly and helped me a lot. I would recommend my family and friends to stay here. It’s so nice and quiet here. "
Canada
Timothy
The price is ￥4,822
￥7,745 total
Jul 20 - Jul 21
PRAGA APARTMENTS
Living area

13. NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
2.0 out of 10, (1 review)
"Deben haber un mejor desayuno, al menos frutas. No es tan bueno como parecía"
United States
Damariz
The price is ￥7,449
￥7,773 total
Aug 17 - Aug 18
NP Hotel & Suites
Exterior

14. Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ￥7,793
￥7,793 total
Jul 19 - Jul 20
Hotel La Ria Durán
Economy Triple Room | WiFi (free), bed sheets

15. Hotel Dorado

Hotel Dorado
2.0 star property
Olmedo, 2.4 km from Puerto Santa Ana
8.8 out of 10, Excellent, (20 reviews)
"I had a great stay here. I thought the traffic noise would be too loud but I slept like a baby. I get the pleasure of staying here again in three weeks."
United States
Robert
The price is ￥2,356
￥2,356 total
Aug 16 - Aug 17
Hotel Dorado
Comfort Double Room | In-room safe, desk, WiFi (free), bed sheets

16. Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.6 out of 10, Excellent, (43 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
The price is ￥4,895
￥5,219 total
Jul 19 - Jul 20
Hotel GH Alexander
Terrace/patio

17. Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (57 reviews)
"Nice room, close to the airport. Was a bit noise at night because of the street dogs"
Australia
pavel
The price is ￥4,676
￥4,676 total
Aug 2 - Aug 3
Casa Serena
32-inch Smart TV with digital channels, first-run movies

18. Departamentos en la Garzota

Departamentos en la Garzota
4.5 star property
Garzota, 4 km from Puerto Santa Ana
The price is ￥4,676
￥5,164 total
Aug 2 - Aug 3
Departamentos en la Garzota
Front of property

19. Hotel The Royalty Inn

Hotel The Royalty Inn
4.0 star property
Simón Bolívar, 3.1 km from Puerto Santa Ana
8.4 out of 10, Very Good, (11 reviews)
"Good for a single night stay , close to the airport and mall "
United States
Jonathan
The price is ￥6,575
￥10,310 total
Jul 20 - Jul 21
Hotel The Royalty Inn
Ecotours

20. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
8.4 out of 10, Very Good, (8 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is ￥6,592
￥6,916 total
Aug 17 - Aug 18
Fortune Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Chocolate Museum while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or World Trade Center.

Top Puerto Santa Ana Hotel Reviews

Hilton Colon Guayaquil

Hilton Colon Guayaquil

10/10 Excellent
"well located and safe enviroment"
Carlos 5-night trip
Posted 8 hours ago
Hilton Colon Guayaquil

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 83 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.