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Guadalupe Vacation Rentals

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Check prices for these dates

In two weeks
Jan 2 - Jan 4
In two months
Feb 13 - Feb 15
In three months
Mar 13 - Mar 15
In four months
Apr 10 - Apr 12

Our top choices for Guadalupe vacation rentals

Standard Cabin | Laptop workspace, bed sheets
CAMPISMO PRAIA GRANDE

Camping in Malanza

CAMPISMO PRAIA GRANDE
1.0 star property
8.6 out of 10, Excellent, (4)
"A little piece of paradise on an amazing beach. "
United Kingdom
John
The price is ￥7,631
￥8,917 total
includes taxes & fees
Dec 20 - Dec 21
CAMPISMO PRAIA GRANDE
Interior
CHALET 19_ An inclusive tourism, an experience for life!

Chalet in São Tomé

CHALET 19_ An inclusive tourism, an experience for life!
The price is ￥7,298
￥13,502 total
includes taxes & fees
Jan 2 - Jan 3, 2026
CHALET 19_ An inclusive tourism, an experience for life!
Property grounds
endless horizon - Cozy house in charming Santana with WiFi

Vacation Home in Santana

endless horizon - Cozy house in charming Santana with WiFi
10.0 out of 10, Exceptional, (1)
"We really enjoyed our stay at the Endless Horizon. Joao and Alexander were always there to help out with things. We loved the high ceilings and of course the amazing view. The bed was very comfortable and the shower was wonderful; specious and with nice hot water. We would stay there again."
United States
Silvard K.
The price is ￥14,597
￥23,355 total
includes taxes & fees
Jan 2 - Jan 3, 2026
endless horizon - Cozy house in charming Santana with WiFi
Iron/ironing board, free WiFi
Alojamento Santos Silva

Vacation Home in São Tomé

Alojamento Santos Silva
3.0 star property
The price is ￥45,014
￥52,516 total
includes taxes & fees
Dec 26 - Dec 27
Alojamento Santos Silva
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Guadalupe Hotel Reviews

Pestana São Tomé

Pestana São Tomé

10/10 Excellent
"Wonderful stay, great staff, easy, relaxing delightful."
alexander 5-night trip
Posted 10 days ago
Pestana São Tomé

Find out more about Guadalupe

Search for holiday rentals in Guadalupe on Expedia! You can easily find your home rentals, villas, holiday apartments in Guadalupe using one of the methods below:

  • View our selection of featured holiday rentals in Guadalupe
  • Use the map to find apartments and other holiday homes in the Guadalupe neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Guadalupe while they last

Look no further and take a look at our great range of rental properties in Guadalupe!

Frequently asked questions

Are there vacation rentals in Guadalupe?

Yes, there are vacation rentals close to popular attractions in Guadalupe, or you can choose a secluded option if you're looking for relaxation.

What's the top vacation rental that Guadalupe has to offer?

Alojamento Santos Silva : You might want to consider this vacation home rental near Guadalupe, which offers an outdoor pool, a garden, and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave, and kitchenware.

What’s there to see and do in Guadalupe?

Explore the area and family-friendly sights such as Cloçon Téla Chocolate Factory, or get out into nature at a spot like Pico São Tomé. In the larger area, you’ll find Cathedral of São Tomé and São Sebastião Museum.

What’s a vacation rental in Guadalupe like?

Vacation rentals are privately owned properties you can stay in for a long or short time in Guadalupe. Vacation rentals provide amenities such as laundry facilities and kitchens so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of security away from public hotel elevators and busy front desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for family trips or small group gatherings.