The Best Hotels Closest to Greenville Hospital System in Simpsonville for 2026

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Our top choices for Greenville Hospital System hotels

A reception desk with a modern design, featuring a light wood finish and illuminated panels.

An outdoor patio area with tables and chairs, a building with large windows, and a clear sky.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with a large bed, a desk with a chair, a TV, and a window with blinds.

1. Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

1.3 km from Greenville Hospital System

Alicia

￥20,545

￥22,599 total

includes taxes & fees

Sep 27 - Sep 28

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A gym with treadmills, stationary bikes, and exercise balls.

A modern lobby with a blue sofa, a round coffee table, and a brown armchair.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

2. Fairfield Inn & Suites by Marriott Greenville Simpsonville

0.9 km from Greenville Hospital System

Simone

￥12,250

￥13,477 total

includes taxes & fees

Sep 13 - Sep 14

A modern restaurant with high tables and booths, a bar area, and a visible kitchen in the background.

A Hampton Inn hotel with a modern facade, a welcoming entrance, and a flagpole with the American flag.

A modern hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A modern hotel room with a grey sofa, a small table, a TV, and a kitchen area with a microwave and a painting.

3. Hampton Inn Simpsonville

0.7 km from Greenville Hospital System

Matthew

￥16,117

￥19,937 total

includes taxes & fees

Sep 21 - Sep 22

A hotel room with a sofa, a small round table, a bed with two pillows, a nightstand, a lamp, a TV, and a curtain.

An indoor swimming pool with clear blue water, surrounded by a modern interior with white walls, recessed lighting, and large windows.

A reception area with a mosaic-tiled counter, multiple pendant lights, and a laptop on the counter.

A modern living room with a stone wall, a flat-screen TV, a fireplace, and large windows with a view of the street.

4. Comfort Suites Simpsonville - Greenville

1.5 km from Greenville Hospital System

Lesa

￥15,340

￥16,873 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a desk, a chair, and a small kitchenette.

A Fairfield by Marriott hotel with a modern design, featuring a parking lot and a clear blue sky.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with multiple balconies.

A hotel with a covered parking area, stone pillars, and a two-story building with balconies.

5. Quality Inn Simpsonville - Greenville

0.8 km from Greenville Hospital System

Robert

￥10,631

￥12,306 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk with a computer, a TV, and a window with curtains.

A lobby with a check-in counter, seating area, and a computer station.

A modern hotel with a curved building, a stone bridge, and a river.

6. Motel 6 Simpsonville, SC - Greenville

0.9 km from Greenville Hospital System

BRITTANYLEIGH

￥11,497

￥12,647 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, a brown leather chair, a nightstand, a desk with a chair, and a cityscape painting on the wall.

A Days Inn with a blue door, a bench outside, and a small tree in the front.

A modern restaurant with a counter, seating area, and a ceiling fan.

A reception area with a counter, framed artwork, and a 'Hello Sunshine' sign.

7. Days Inn by Wyndham Simpsonville

0.8 km from Greenville Hospital System

Benjamin

￥11,734

￥12,907 total

includes taxes & fees

Sep 25 - Sep 26

A multi-story hotel with a prominent sign for "Woodspring Suites."

A hallway with a white reception desk, a computer on a shelf, and a door with a glass panel.

A hallway with a wooden cabinet, a white door, and a green wall with a mirror and small potted plants.

Two vending machines in a hallway with a sign that reads "VENDORS".

8. WoodSpring Suites Greenville Simpsonville

2.8 km from Greenville Hospital System

Gary

￥9,812

￥10,793 total

includes taxes & fees

Sep 13 - Sep 14

A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

A bar with multiple shelves of liquor bottles and glasses hanging above.

A modern living room with a fireplace, seating area, and a bar with shelves of bottles.

A large, two-story house with a symmetrical facade, large windows, and a central entrance.

9. Hotel Hartness

13.5 km from Greenville Hospital System

Cornelius

￥23,495

￥31,715 total

includes taxes & fees

Oct 4 - Oct 5

A large brick house with a well-maintained garden, a welcoming entrance, and a street sign indicating the address.

A dining room with a large table set for six, surrounded by chairs. A fireplace with a mantle and a mirror above it is visible. The room has red walls and a patterned rug on the floor.

A four-poster bed with white drapes, a wooden desk, a chair, and a small table.

A two-story brick house with a well-maintained garden, a driveway, and a street sign for Pettigru Street.

10. Pettigru Place Bed & Breakfast

19.3 km from Greenville Hospital System

Debbie

￥37,826

￥41,609 total

includes taxes & fees

Sep 12 - Sep 13

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

11. Best Western Plus Greenville I-385 Inn & Suites

14.7 km from Greenville Hospital System

Sara

￥11,530

￥12,683 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

A modern lounge area with comfortable seating, a round table, and a large screen.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped flower beds.

A modern bar area with a wooden counter, a digital menu board, and a variety of liquor bottles.

12. Courtyard by Marriott Greenville Mauldin

10 km from Greenville Hospital System

Leticia

￥18,245

￥20,070 total

includes taxes & fees

Sep 13 - Sep 14

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A modern living area with a sofa, chairs, a TV, and a fireplace.

A swimming pool with lounge chairs and a no diving sign.

A multi-story hotel with a central courtyard, a pool, and a parking area.

13. Comfort Suites Greenville Airport

15.1 km from Greenville Hospital System

Chandler

￥14,269

￥16,165 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

14. Drury Inn & Suites Greenville

12.9 km from Greenville Hospital System

Gohan

￥20,697

￥22,767 total

includes taxes & fees

Sep 13 - Sep 14

A modern kitchen with hanging light fixtures and bar seating.

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.

A modern bar area with a central island, bar stools, and overhead lighting.

15. DoubleTree by Hilton Greenville Woodruff Road

12.6 km from Greenville Hospital System

Jeffery

￥18,733

￥21,222 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

A hotel lobby with a reception desk, a patterned carpet, and a large abstract wall art piece.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

16. Hampton Inn & Suites Greenville Airport, SC

16 km from Greenville Hospital System

Kristina

￥16,168

￥18,318 total

includes taxes & fees

Sep 20 - Sep 21

A modern outdoor seating area with a glass-top coffee table, blue sofas, and orange patterned cushions.

A modern lobby with a blue sofa, teal armchairs, hanging lights, and a seating area with round chairs.

A modern lobby with a reception desk, seating areas, and a large window offering a view.

17. Tru by Hilton Greenville Woodruff Road

12.8 km from Greenville Hospital System

Sandra

￥14,175

￥17,042 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio area with seating and tables, covered by a wooden pergola with string lights.

A modern hotel with a covered entrance and multiple floors.

A modern hotel lobby with a central seating area, a kitchenette, and a TV screen.

A hotel room with a large bed, bedside tables, a desk, and a bathroom visible through an open door.

18. Home2 Suites by Hilton Greenville Airport

15.5 km from Greenville Hospital System

Brian

￥19,990

￥22,650 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.

A reception area with marble reception desks, a cityscape poster, wooden shelving with toiletries, and pendant lighting.

A modern kitchen with a refrigerator, coffee machine, and various food items.

A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.

19. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

14 km from Greenville Hospital System

Jalen

￥12,446

￥14,101 total

includes taxes & fees

Sep 13 - Sep 14

A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.

A snack and beverage display with various snacks and drinks.

A hotel pool area with lounge chairs, a flag, and a sunset view.

A cafe with a checkered floor, wooden cabinets, and hanging pendant lights.

20. Hampton Inn Greenville I-385 - Woodruff Rd.

12.1 km from Greenville Hospital System

Anne

￥15,590

￥17,666 total

includes taxes & fees

Sep 21 - Sep 22

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Compare popular hotels close to Greenville Hospital System

Property	Star rating	Guest rating
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG	9.4 Exceptional 557 reviews	View
Fairfield Inn & Suites by Marriott Greenville Simpsonville	9.0 Wonderful 785 reviews	View
Hampton Inn Simpsonville	8.8 Excellent 700 reviews	View
Comfort Suites Simpsonville - Greenville	8.2 Very Good 871 reviews	View
Quality Inn Simpsonville - Greenville	7.6 Good 234 reviews	View

Top Greenville Hospital System Hotel Reviews

Newly updated! Walk to downtown Simpsonville.

10/10 Excellent

"Great location and host was very accommodating! Couldn’t speak more highly for our stay. 10/10 would stay again."

Fairfield Inn & Suites by Marriott Greenville Simpsonville

8/10 Good

"Front desk staff was great upon check in. The body wash container was empty but I loved the shower head."

Motel 6 Simpsonville, SC - Greenville

10/10 Excellent

"Everything was awesome"

4 bedrooms, Simpsonville, family-friendly, great fenced back yard with fire pit

10/10 Excellent

"Excellent location and house was awesome - loved the backyard too."

Hampton Inn Simpsonville

8/10 Good

"This is our second stay at the property this year. Our room was fine but we were staying with friends and the baseboards weren't attached to the wall and the ceiling was falling down in the bathroom. We did however check in on Tuesday and had to ask for room service on Friday. Says you will get room service every other day. Also, I don't mind using towels for 2 days, but I really don't want to have to use washcloths more than once. We were only given 2 for two people.Had to ask at the desk."

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

10/10 Excellent

"The mattress was a bit uncomfortable but the pillows were very comfortable"

Modern Farmhouse in Downtown Simpsonville, SC

10/10 Excellent

"Great place in the heart of lovely Simpsonville, quiet, clean and comfortable."

The Cotton Mill Cottage - charming 2 bedroom blocks from downtown Simpsonville

10/10 Excellent

"This was a great property. Wonderful kitchen & nice quiet street.Great for short stay & would be good for longer stays."

Spacious 5-BR Retreat in Simpsonville, SC – Perfect for Gatherings & Getaways

10/10 Excellent

"House was perfect for our family of 6 adults (3couples) and 4 teenagers attending a family wedding in the area."

Other attractions near Greenville Hospital System

Fairview Station

You can browse for the perfect souvenirs at Fairview Station during your trip to Simpsonville. Take in the live music and sunrises in the area.

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Piedmont Plaza

You can browse for the perfect souvenirs at Piedmont Plaza during your visit to Simpsonville. Experience the area's live music and theater scene.

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Simpsonville Commons

You can do some window-shopping at Simpsonville Commons during your trip to Simpsonville. Take in the live music and sunrises in the area.

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Chancellor's The Commons

You can enjoy retail therapy at Chancellor's The Commons during your trip to Simpsonville. Experience the area's live music and theater scene.

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Hillcrest Pointe

You can search for that perfect souvenir at Hillcrest Pointe during your trip to Simpsonville. Experience the area's live music and theater scene.

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Regal Simpsonville

You can take time to visit Regal Simpsonville during your travels to Simpsonville. Experience the area's live music and theater scene.

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Foxwood Recreation Area

Foxwood Recreation Area is just one of the places to see in Simpsonville, so why not enjoy the other things to explore during your travels? Experience the area's live music and theater scene.

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Fairview Commons

You can search for that perfect souvenir at Fairview Commons during your trip to Simpsonville. Experience the area's live music and theater scene.

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Frequently asked questions

What's the area like around Greenville Hospital System?

Greenville Hospital System is located in Simpsonville. If you're looking for a convenient place to stay, check out the 15 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Greenville Hospital System?

Quality Inn Simpsonville - Greenville is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.8 km) from Greenville Hospital System. Other good choices close by include Fairfield Inn & Suites by Marriott Greenville Simpsonville and Hampton Inn Simpsonville.

How many hotels will I be able to find near Greenville Hospital System?

Expedia has 15 hotels and other accommodations within a mile from Greenville Hospital System.

If I need to cancel the hotel reservation for my stay near Greenville Hospital System, will I receive a refund?

Yes, most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals near Greenville Hospital System.

Where can I learn more about changing or cancelling my trip in the area near Greenville Hospital System?

To access more information about picking new dates or cancelling your stay near Greenville Hospital System, head over to our customer service page.

What can I see and do near Greenville Hospital System?

You can watch performances at Heritage Park, CCNB Amphitheatre, and Brookwood Amphitheater if you're interested in local theater. You'll have countless hours of family fun at Simpsonville Arts Center, Younts Center for Performing Arts, and Discovery Island Water Park. A shopping trip to Simpsonville Commons, Martin Farm, or Fairview Station, might be the perfect place to find that souvenir you've been looking for.

Find hotels near Greenville Hospital System, Simpsonville from ￥10,793

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Our top choices for Greenville Hospital System hotels

1. Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

2. Fairfield Inn & Suites by Marriott Greenville Simpsonville

3. Hampton Inn Simpsonville

4. Comfort Suites Simpsonville - Greenville

5. Quality Inn Simpsonville - Greenville

6. Motel 6 Simpsonville, SC - Greenville

7. Days Inn by Wyndham Simpsonville

8. WoodSpring Suites Greenville Simpsonville

9. Hotel Hartness

10. Pettigru Place Bed & Breakfast

11. Best Western Plus Greenville I-385 Inn & Suites

12. Courtyard by Marriott Greenville Mauldin

13. Comfort Suites Greenville Airport

14. Drury Inn & Suites Greenville

15. DoubleTree by Hilton Greenville Woodruff Road

16. Hampton Inn & Suites Greenville Airport, SC

17. Tru by Hilton Greenville Woodruff Road

18. Home2 Suites by Hilton Greenville Airport

19. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

20. Hampton Inn Greenville I-385 - Woodruff Rd.

Compare popular hotels close to Greenville Hospital System

Top Greenville Hospital System Hotel Reviews

Newly updated! Walk to downtown Simpsonville.

Fairfield Inn & Suites by Marriott Greenville Simpsonville

Motel 6 Simpsonville, SC - Greenville

4 bedrooms, Simpsonville, family-friendly, great fenced back yard with fire pit

Hampton Inn Simpsonville

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Modern Farmhouse in Downtown Simpsonville, SC

The Cotton Mill Cottage - charming 2 bedroom blocks from downtown Simpsonville

Spacious 5-BR Retreat in Simpsonville, SC – Perfect for Gatherings & Getaways

Other attractions near Greenville Hospital System

Fairview Station

Piedmont Plaza

Simpsonville Commons

Chancellor's The Commons

Hillcrest Pointe

Regal Simpsonville

Foxwood Recreation Area

Fairview Commons

Frequently asked questions