Find Resorts & Hotels with Spas in Florida Keys
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Florida Keys Resorts & Hotels with Spas
Top Florida Keys Resorts & Hotels with Spas
Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
8.6 out of 10, Excellent, (2665)
The price is ￥27,359
￥40,801 total
includes taxes & fees
Aug 25 - Aug 26
Casa Marina Key West, Curio Collection by Hilton
Casa Marina Key West, Curio Collection by Hilton
8.4 out of 10, Very Good, (263)
The price is ￥31,534
￥44,384 total
includes taxes & fees
Aug 13 - Aug 14
Cheeca Lodge & Spa
Cheeca Lodge & Spa
9.0 out of 10, Wonderful, (1147)
The price is ￥25,116
￥38,278 total
includes taxes & fees
Aug 14 - Aug 15
Reefhouse Resort & Marina
Reefhouse Resort & Marina
9.2 out of 10, Wonderful, (1292)
The price is ￥32,517
￥42,521 total
includes taxes & fees
Jul 31 - Aug 1
Ocean Key Resort - A Noble House Resort
Ocean Key Resort - A Noble House Resort
9.2 out of 10, Wonderful, (1004)
The price is ￥39,941
￥55,792 total
includes taxes & fees
Aug 26 - Aug 27
Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
9.2 out of 10, Wonderful, (1008)
The price is ￥39,080
￥52,967 total
includes taxes & fees
Aug 28 - Aug 29
Playa Largo Resort & Spa, Autograph Collection
Playa Largo Resort & Spa, Autograph Collection
9.0 out of 10, Wonderful, (1000)
The price is ￥39,050
￥52,117 total
includes taxes & fees
Aug 17 - Aug 18
Tranquility Bay Beachfront Hotel and Resort
Tranquility Bay Beachfront Hotel and Resort
8.8 out of 10, Excellent, (1001)
The price is ￥33,297
￥47,021 total
includes taxes & fees
Aug 20 - Aug 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Florida Keys Hotel Reviews
Chesapeake Beach Resort
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Resorts & Hotels with Spas
Find More Hotels near Florida Keys
More Hotel Options in Florida Keys
- Adults Only Resorts & Hotels in Florida Keys
- Adventure Hotels in Florida Keys
- All-inclusive Hotel in Florida Keys
- Beach Hotels in Florida Keys
- Boutique Hotels in Florida Keys
- Business Hotels in Florida Keys
- Casinos in Florida Keys
- Cheap Hotels in Florida Keys
- Family Hotels in Florida Keys
- Gay friendly Hotels in Florida Keys
- Golf Hotels in Florida Keys
- Green Hotels in Florida Keys
- Historic Hotels in Florida Keys
- Hotel Wedding Venues in Florida Keys
- Hotel with a Concierge in Florida Keys
- Hotels with Bars in Florida Keys
- Hotels with Early Check-in in Florida Keys
- Hotels with Free Parking in Florida Keys
- Hotels with Hot Tubs in Florida Keys
- Hotels with Waterslides in Florida Keys
- Hotels with WiFi in Florida Keys
- Hotels with a Pool in Florida Keys
- Hotels with smoking rooms in Florida Keys
- Luxury Hotels in Florida Keys
- Pet-friendly Hotels in Florida Keys
- Romantic Hotels in Florida Keys
- Scuba Diving in Florida Keys
- Shopping Hotels in Florida Keys
- Ski Hotels in Florida Keys
More Accommodation Types in Florida Keys
- Vacation Homes in United States of America
- Condo Rentals in United States of America
- Apartments in United States of America
- Cabin Rentals in United States of America
- Cottages in United States of America
- Villas in United States of America
- Motels in United States of America
- Resorts in United States of America
- Aparthotels in United States of America
- B&B in United States of America
- Guest Houses in United States of America
- Chalets in United States of America
- Farmstay in United States of America
- Lodges in United States of America
- RV Parks in United States of America
- Houseboats in United States of America
- Inns in United States of America
- Town Houses in United States of America
- Hostels in United States of America
- Condo Resorts in United States of America
- Castles in United States of America
- Residences in United States of America
- Holiday Park Resorts in United States of America
- Ranches in United States of America
- Safari Tentalow in United States of America
- Treehouses in United States of America
- Country Houses in United States of America
- Capsule Hotels in United States of America
- Riads in United States of America
Hotels near popular Florida Keys Attractions
- Hotels near Duval Street
- Hotels near Southernmost Point
- Hotels near Smathers Beach
- Hotels near John Pennekamp Coral Reef State Park
- Hotels near Florida Keys Beaches
- Hotels near Sombrero Beach
- Hotels near South Beach
- Hotels near Ernest Hemingway Home and Museum
- Hotels near Fort Zachary Taylor Historic State Park
- Hotels near Jimmy Johnson's Big Chill
Florida Keys Hotels by Star Rating
Explore more hotels
- Fairfield Inn & Suites by Marriott Marathon Florida Keys
- Bayside Inn Key Largo
- Waterside Suites & Marina
- Lime Tree Bay Resort
- Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
- Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
- Rock Reef Resort
- Reefhouse Resort & Marina
- La Siesta Resort & Villas
- Rainbow Bend Resort
- Tranquility Bay Beachfront Hotel and Resort
- The Pelican Key Largo Cottages
- Drift Hotel
- Creekside Inn Islamorada
- Coconut Cay Resort & Marina
- Yacht Haven Marina
- Hadley Resort and Marina
- Marina Del Mar Resort and Marina
More ways to book
Expedia's Latest Trends
Hotels
Flights
Cars
Packages