A cozy reading nook with a brick wall, a wooden bookshelf filled with books, a small armchair, and a framed photograph.

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Check availability on Florence Luxury Hotels

Tonight
Oct 19 - Oct 20
Tomorrow
Oct 20 - Oct 21
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1
No exact matches found, but these alternatives could be just right

Recommended hotels in Florence

Main floor living room and open concept kitchen and dining room.
Kitchen is equipped with everything you need to make an excellent meal. You will love cooking on the gas stove. We also provide some of the most popular kitchen tools such as bread maker, air fryer, pancake griddle and more! Check out our amenities list to see everything we have to offer.
Exterior
Alternate view of the Master bedroom shows off the balcony door and elegant style the room has to offer. This room offers blackout curtains and a smart TV.

1. Modern Waterfront Mansion with Private Dock, kayak, paddle board and ping pong

Modern Waterfront Mansion with Private Dock, kayak, paddle board and ping pong
Florence
￥65,420
￥131,479 total
includes taxes & fees
Oct 20 - Oct 21
Modern Waterfront Mansion with Private Dock, kayak, paddle board and ping pong
A hotel with a large pool area, a water tower, and a dome structure.
A restaurant with a curved layout, large windows offering a view of a body of water, and a bar area with a view.
A spacious living area with large windows, a central coffee table, sofas, and armchairs.
A modern bathroom with a large mirror, two sinks, a bathtub, a shower, and a fireplace.

2. Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa
East Florence
￥45,668
￥52,518 total
includes taxes & fees
Oct 25 - Oct 26
Renaissance Shoals Resort & Spa
A spacious lounge with a fireplace, leather sofas, and a bar area.
A coffee shop with a large sign reading "COFFEE" and a smaller sign below stating "HOT SHAVES! CLEAN HANDS! ALWAYS FRESH!".
A spacious bedroom with a large bed, a chandelier, and a stone wall.
A teal armchair with wooden legs, a small round table with a white vase, and a hanging lamp.

3. GunRunner Boutique Hotel

GunRunner Boutique Hotel
Florence
￥32,547
￥37,571 total
includes taxes & fees
Oct 25 - Oct 26
GunRunner Boutique Hotel
A restaurant interior with a bar area, seating, and a counter with a coffee machine.
A restaurant with a large aircraft model mural on the wall, wooden tables, and chairs.
A bedroom with a brick wall, a dark blue headboard, and patterned pillows.
The Stricklin Hotel with a sign for Big Bad Breakfast.

4. The Stricklin Hotel

The Stricklin Hotel
Florence
￥24,191
￥27,927 total
includes taxes & fees
Oct 20 - Oct 21
The Stricklin Hotel
A snack bar with shelves of snacks and a refrigerator with beverages.
A modern room with a wooden floor, a white desk with a coffee machine, a small fridge, and a window with a view of the outside.
A gym with cardio machines, weight benches, and a wall-mounted medicine ball rack.
A modern hotel room with a large bed, a desk, a chair, a window with a view, and a wall-mounted lamp.

5. Hampton Inn Florence Midtown near University of North Alabama

Hampton Inn Florence Midtown near University of North Alabama
Florence
￥20,603
￥23,692 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn Florence Midtown near University of North Alabama
A modern kitchen with wooden cabinets, a countertop with various appliances, and a view of the outdoors.
A modern kitchen with a sink, microwave, and coffee maker.
An indoor swimming pool with clear water, tiled walls, and a lifeguard chair.
A reception area with two wooden reception desks, a blue rug, and a modern interior design.

6. Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Florence
￥18,646
￥21,443 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
A hotel lobby with a seating area, a reception desk, and a check-in counter.
A hotel room with a bed, a TV, a desk with a chair, a coffee maker, and a map on the wall.
Lobby
A modern hotel lobby with a bar area, seating arrangements, and a fireplace.

7. Residence Inn Florence Marriott

Residence Inn Florence Marriott
East Florence
￥18,488
￥21,261 total
includes taxes & fees
Nov 8 - Nov 9
Residence Inn Florence Marriott
A modern kitchen with dark cabinets, a stainless steel refrigerator, a microwave, and a large island with bar stools.
A cozy room with a brick wall, a window with a view of buildings, a couch with a blanket, a guitar, and a speaker.
A spacious living area with a brick wall, a large window, a kitchen area with a bar, and a comfortable seating arrangement.
A parking area with cars and a motorcycle, a gated entrance, and a building with a white facade.

8. Historic downtown loft with exposed brick on N. Court St.

Historic downtown loft with exposed brick on N. Court St.
Florence
￥26,231
￥50,985 total
includes taxes & fees
Nov 1 - Nov 2
Historic downtown loft with exposed brick on N. Court St.
A kitchen with white cabinetry, stainless steel appliances, and a herringbone wood floor.
A single-story brick building with a flat roof, a front porch, and a small front yard with scattered leaves.
A dining area with a wooden table and chairs, a chandelier, and a kitchen in the background.
A bedroom with a bed, a ceiling fan, a TV on the wall, and a window with curtains.

9. Spacious 4-bedroom house in lakefront subdivision on one and a half acres

Spacious 4-bedroom house in lakefront subdivision on one and a half acres
Florence
￥27,772
￥58,916 total
includes taxes & fees
Oct 20 - Oct 21
Spacious 4-bedroom house in lakefront subdivision on one and a half acres
A modern kitchen with a large island, bar stools, stainless steel appliances, and a view of the outdoors.
A spacious living room with a brown leather sofa, a matching ottoman, and a round coffee table. A ceiling fan and a large window with blinds are visible.
A single-story house with a front porch, a brick foundation, and a clear pathway leading to the entrance.
A modern kitchen with a stainless steel refrigerator, wooden dining table, and chairs.

10. Lagniappe in Florence

Lagniappe in Florence
Florence
￥24,177
￥50,124 total
includes taxes & fees
Oct 20 - Oct 21
Lagniappe in Florence
View all properties

Find out more about Florence

Florenceand its attractions for luxury travelers

Florence, Alabama, is a hidden gem for luxury travelers seeking a blend of cultural richness and outdoor adventure. Start your exploration at the Frank Lloyd Wright-designed Rosenbaum House, which offers guided tours showcasing its stunning architecture. Next, indulge in the arts at the Florence Museum, where you can view an impressive collection of American art and Southern regionalism. For nature enthusiasts, the scenic trails at McFarland Park provide a perfect backdrop for leisurely walks or picnics by the Tennessee River. Golf aficionados will appreciate the meticulously maintained courses at the Florence Golf and Country Club, where you can enjoy a round in a picturesque setting. After a day of exploration, unwind in the elegant rooms at the Renaissance Tower, located in the heart of downtown Florence. This hotel offers a blend of modern luxury and Southern hospitality, making it an ideal base for your adventures. With its prime location, you can easily stroll to nearby restaurants and boutique shops, ensuring a comfortable and convenient stay.

Find the best luxury hotels and resorts in Florence

For travelers seeking a luxurious experience in Florence, Alabama, these top hotels offer exquisite amenities and exceptional service. Each hotel promises a memorable stay filled with comfort and sophistication.Renaissance Shoals Resort and Spa

  • Why it's great for a luxury retreat: For an indulgent getaway, Renaissance Shoals Resort and Spa stands out with its impressive review rating of 9.0. Travelers can revel in luxury amenities like stunning river views, designer toiletries, and a dedicated concierge service, ensuring their every need is met. The resort structure enhances the feeling of exclusivity and relaxation.
  • Other amenities: Beyond its luxurious features, guests will enjoy a range of amenities, including both indoor and outdoor pools, a hot tub, and poolside bar for refreshing drinks. The spa offers hydrotherapy treatments, manicures, and pedicures, along with a range of body treatments. Additional conveniences such as a rooftop garden, terrace, and 24-hour airport transportation make this resort a top choice for travelers.
  • Neighborhood: East Florence
  • Nearby attractions: Shoals Conference Center - 0.06 miles, River Heritage Park - 0.07 miles, Renaissance Tower - 0.18 miles

The Stricklin Hotel

  • Why it's great for a luxury retreat: The Stricklin Hotel is a perfect choice for luxury travelers looking for a cozy yet upscale stay. With an excellent review rating of 8.8, guests will enjoy high-end amenities such as Egyptian cotton sheets, designer toiletries, and premium bedding that elevate their experience to pure comfort.
  • Other amenities: In addition to its luxurious offerings, The Stricklin Hotel provides daily housekeeping, free toiletries, and convenient nearby parking. Guests can take advantage of the historical district location, making it easy to explore the rich culture of Florence. The hotel also features an arcade game room for some light entertainment during your leisure time.
  • Nearby attractions: Shoals Community Theater - 0.2 miles, Pope's Tavern Museum - 0.17 miles, Kennedy-Douglass Center for the Arts - 0.17 miles

GunRunner Boutique Hotel

  • Why it's great for a luxury retreat: GunRunner Boutique Hotel is an ideal luxury retreat for travelers who appreciate unique and stylish accommodations. Rated 8.6 by guests, this boutique hotel offers premium bedding, plush bathrobes, and designer toiletries, ensuring a pampered stay. The deep soaking bathtubs provide an extra touch of relaxation after a day of exploring.
  • Other amenities: In addition to its luxurious touches, guests can enjoy in-room massages, facial treatments, and a dedicated spa onsite. The hotel also features a rooftop terrace and balconies, offering lovely views for guests to unwind. Self-parking is available, making it easy to come and go as you please. With a focus on comfort and style, GunRunner Boutique Hotel is a perfect choice for luxury travelers.
  • Nearby attractions: Shoals Community Theater - 0.18 miles, Pope's Tavern Museum - 0.41 miles, Kennedy-Douglass Center for the Arts - 0.25 miles

Top Florence Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Florence?
Let Expedia help you arrange your flight to Muscle Shoals, AL (MSL-Northwest Alabama Regional) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a vacation, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the live music which Florence is known for.
When can I expect good weather in Florence?
Planning for the weather is a good way to make your trip to Florence relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 45°F. Average annual precipitation for Florence is 62 inches.
What's there to see and do in Florence?
Take in some sights and attractions while you're in Florence by visiting Shoals Conference Center, Regency Square Mall, and Wilson Lake. If you have a little extra time during your trip, you might want to check out Pickwick Lake and Tennessee River.

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