Find hotels near Edisto Island Serpentarium, Edisto Island from ￥51,058

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Dec 14 - Dec 15
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Dec 15 - Dec 16
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Dec 19 - Dec 21
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Our top choices for Edisto Island Serpentarium hotels

Lounge
Charleston Kiawah Island/Andell Inn

Charleston Kiawah Island/Andell Inn

Charleston Kiawah Island/Andell Inn
3.5 star property
13.4 km from Edisto Island Serpentarium
9.6 out of 10, Exceptional, (518)
"Spotless room, friendly staff, amazing breakfast, great access to shopping and restaurants were all the things that made our stay wonderful! We want to return!"
United States
John
The price is ￥46,587
￥55,373 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Charleston Kiawah Island/Andell Inn
Bar (on property)
The Dunlin, Auberge Collection

The Dunlin, Auberge Collection

The Dunlin, Auberge Collection
5.0 star property
16.4 km from Edisto Island Serpentarium
9.8 out of 10, Exceptional, (30)
"Beautiful hotel, had a perfect stay!"
United States
Madison
The Dunlin, Auberge Collection
Children's play area - outdoor
The Sanctuary at Kiawah Island Golf Resort

The Sanctuary at Kiawah Island Golf Resort

The Sanctuary at Kiawah Island Golf Resort
5.0 star property
18.3 km from Edisto Island Serpentarium
9.6 out of 10, Exceptional, (227)
"all was excellent."
United States
michael
The price is ￥45,185
￥51,058 total
includes taxes & fees
Dec 15 - Dec 16
The Sanctuary at Kiawah Island Golf Resort
House | 3 bedrooms, Internet
The Breeze in Seabrook Island

The Breeze in Seabrook Island

The Breeze in Seabrook Island
2.0 star property
9.9 km from Edisto Island Serpentarium
The price is ￥20,884
￥67,334 total
includes taxes & fees
Dec 15 - Dec 16
The Breeze in Seabrook Island
House | 1 bedroom, Internet
Hideout at Shipwatch - On The Beach

Hideout at Shipwatch - On The Beach

Hideout at Shipwatch - On The Beach
2.0 star property
15.3 km from Edisto Island Serpentarium
The price is ￥16,708
￥58,811 total
includes taxes & fees
Dec 15 - Dec 16
Hideout at Shipwatch - On The Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Edisto Island Serpentarium Hotel Reviews

Seaclusion by AvantStay | Walk to the Beach

Seaclusion by AvantStay | Walk to the Beach

10/10 Excellent
"Amenities were great, customer service was excellent"
April B. 7-night trip
Posted 12 days ago
Seaclusion by AvantStay | Walk to the Beach

Hotels near other Edisto Island Serpentarium attractions

Botany Bay Plantation

4.3/5 (13 reviews)
Explore the great outdoors at Botany Bay Plantation, a lovely green space in Edisto Island. Stroll along the beaches in this relaxing area, or seek out the fishing spots.
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With These Hands Gallery

You can spend time browsing the exhibits at With These Hands Gallery during your travels in Edisto Island. Stroll along the beautiful beaches in this relaxing area, or seek out the biking trails.
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Frequently asked questions

What's the area like around Edisto Island Serpentarium?
Edisto Island Serpentarium is located in an area of Edisto Island known for its beautiful beaches. You'll find 190 hotels and other accommodations within a few miles for a convenient home base.
How many hotels can I expect to find near Edisto Island Serpentarium?
Expedia has 190 hotels and other accommodations a few miles from Edisto Island Serpentarium.
If I need to cancel the hotel reservation for my stay near Edisto Island Serpentarium, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review the top deals on offer near Edisto Island Serpentarium.
Where can I learn more about changing or cancelling my trip in the area near Edisto Island Serpentarium?
To access more information about updating your stay near Edisto Island Serpentarium or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Edisto Island Serpentarium?
Attractions like With These Hands Gallery and Edisto Island Museum highlight the local culture. You might plan a visit to Edisto Beach State Park or Botany Bay Plantation Heritage Preserve and Wildlife Management Area while you're in the area. You might also stop by Bohicket Marina, located 7.9 mi (12.7 km) from Edisto Island Serpentarium, or Freshfields Village which is 8.3 mi (13.4 km) away.

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