A coastal landscape with clear turquoise waters, sandy beaches, and volcanic hills.

Vacation Rentals in Santa Cruz

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Our top choices for Santa Cruz vacation rentals

An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (28 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is ￥20,769
￥20,769 total
Oct 19 - Oct 20
Torre Mar Galapagos Boutique Suites
A couple sitting on a wicker sofa outdoors, with a table between them holding breakfast items and a book titled "GALAPAGOS".

2. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is ￥17,810
￥24,142 total
Oct 14 - Oct 15
Modern apartment with 18 feet ceilings and private terrace with view to a park
A neatly made bed with white bedding, two bedside lamps, and a wooden headboard.

3. VILLA MICONIA

VILLA MICONIA
3.0 star property
San Cristobal
The price is ￥25,382
￥25,382 total
Oct 14 - Oct 15
VILLA MICONIA
A patio with a round table and chairs, a blue umbrella, and a potted plant.

4. Suites

Suites
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (25 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is ￥11,950
￥13,219 total
Oct 25 - Oct 26
Suites
A bedroom with a bed, a chair, and a view of the sea through large windows.

5. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is ￥14,278
￥24,352 total
Oct 22 - Oct 23
Suite with spectacular ocean view, you will wake up to the sound of the sea.
A modern kitchen with a dining table, chairs, pendant lights, a refrigerator, and a large window with curtains.

6. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
The price is ￥18,561
￥28,167 total
Oct 14 - Oct 15
Colmena Apartment in downtown Puerto Ayora, Santa Cruz
A modern living room with a large table, a sofa, and a TV mounted on the wall.

7. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is ￥24,272
￥35,060 total
Oct 14 - Oct 15
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
A building with a white exterior, wooden vertical elements, and a cactus plant in the foreground.

8. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is ￥12,850
￥15,230 total
Oct 14 - Oct 15
Villa Galapagos
An aerial view of a marina with numerous boats docked, a pier with umbrellas, and a small building with a red roof.

9. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is ￥40,691
￥74,391 total
Oct 19 - Oct 20
Galapagos Family Vacation 3 BR. Centrally located and Ocean View
A rooftop terrace with a wooden bench, a potted plant, and a view of the cityscape and mountains.

10. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is ￥10,788
￥13,961 total
Oct 15 - Oct 16
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
A multi-story building with a curved facade, balconies with glass railings, and a staircase leading to the upper floors.

11. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is ￥10,946
￥15,761 total
Oct 14 - Oct 15
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

12. Island Life Two-Bedroom Galapagos Casita

Island Life Two-Bedroom Galapagos Casita
Puerto Ayora
10.0 out of 10, Exceptional, (4 reviews)
"The host John was absolutely the BEST. He went above and beyond to make our stay wonderful. The house had everything one would need. "
United States
Trevor K.
The price is ￥27,921
￥31,887 total
Oct 21 - Oct 22
Island Life Two-Bedroom Galapagos Casita
A hotel room with a bed, a blue wall with island artwork, a green door, and a white ceiling.

13. Comfortable and cozy Galarous Island Suite

Comfortable and cozy Galarous Island Suite
Puerto Ayora
The price is ￥13,564
￥16,737 total
Oct 14 - Oct 15
Comfortable and cozy Galarous Island Suite
A rooftop terrace with a wooden bench, a potted plant, and a view of the cityscape and mountains.

14. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is ￥13,008
￥16,181 total
Oct 14 - Oct 15
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
A glass-top table with a chair on a balcony with blue walls and potted plants.

15. Apartments on Galarous Island

Apartments on Galarous Island
Puerto Ayora
The price is ￥14,278
￥17,451 total
Oct 14 - Oct 15
Apartments on Galarous Island
A bedroom with a bed, a wooden wardrobe, a blue laundry basket, and a window with curtains.

16. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is ￥10,946
￥15,761 total
Oct 14 - Oct 15
TWO Bedrooms Apartment ON THE First Floor Forest View
A hotel room with a bed, a sofa, a dresser, a mirror, and a view of an outdoor patio with a table and chairs.

17. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is ￥15,864
￥21,416 total
Oct 14 - Oct 15
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
A hotel room with a blue-themed decor, including a dolphin artwork on the wall, a bed with a white and blue bedspread, and tropical leaf-patterned pillows.

18. Galarous provides you with quality service and a warm welcome in your home

Galarous provides you with quality service and a warm welcome in your home
Puerto Ayora
The price is ￥10,946
￥14,119 total
Oct 14 - Oct 15
Galarous provides you with quality service and a warm welcome in your home
A modern living room with a sofa, ottoman, and coffee table, large windows, and a wooden ceiling beam.

19. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is ￥23,645
￥26,818 total
Oct 14 - Oct 15
Galapagos Coliving Ecuador Casa Tuna
An outdoor patio with artificial grass, a wooden bench, and a hammock.

20. FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is ￥31,728
￥36,329 total
Oct 21 - Oct 22
FAMILY SUITE in Puerto Ayora
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Maidith Galapagos Inn

Maidith Galapagos Inn

10/10 Excellent
"Excellent service, very friendly, and a very good breakfast. Perfectly situated HOTEL."
Edward 1-night trip
Posted 1 hour ago
Maidith Galapagos Inn

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Vacation Apartments in Santa Cruz

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