A large brick building with columns, surrounded by well-maintained grass and trees.

Vacation Rentals in DeSoto County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for DeSoto County vacation rentals

Terrace/patio

1. Private and relax retreat

Private and relax retreat
Arcadia
8.8 out of 10, Excellent, (25 reviews)
"Great place to relax with lots of activities to do in one location. "
United States
Anonymous traveler
The price is ￥22,504
￥76,791 total
includes taxes & fees
Sep 21 - Sep 22
Private and relax retreat
Interior

2. Whispering Pastures Endless Skies

Whispering Pastures Endless Skies
Arcadia
The price is ￥58,605
￥92,655 total
includes taxes & fees
Sep 18 - Sep 19
Whispering Pastures Endless Skies
Village Beach & Harbor Suite | Balcony view

3. The Suites at Fishermen’s Village

The Suites at Fishermen’s Village
3.0 star property
Punta Gorda Isles
9.8 out of 10, Exceptional, (1,322 reviews)
"Great place"
United States
Nidia
The price is ￥23,792
￥26,647 total
includes taxes & fees
Sep 30 - Oct 1
The Suites at Fishermen’s Village
Lake

4. Lake Grassy Inn & Suites

Lake Grassy Inn & Suites
2.5 star property
Lake Placid
8.4 out of 10, Very good, (269 reviews)
"Basic hotel , clean , comfy bed Location and scenery was beautiful "
United States
Jane
The price is ￥18,411
￥20,712 total
includes taxes & fees
Oct 18 - Oct 19
Lake Grassy Inn & Suites
Smart TV, stereo

5. Completely remodeled beautiful waterfront property on canal with dock

Completely remodeled beautiful waterfront property on canal with dock
Port Charlotte
9.6 out of 10, Exceptional, (72 reviews)
"The house was very clean and perfect for our stay. The canal where we could keep the boat in the water was great, close to boat ramps too. There are things there you may would forget to bring, it was cool, well decorated and felt like a home. Jim was very responsive and helpful. 5 star all the way!We look forward to staying here again in the future."
United States
sherron c.
The price is ￥10,549
￥37,603 total
includes taxes & fees
Sep 25 - Sep 26
Completely remodeled beautiful waterfront property on canal with dock
Interior

6. Charming cottage for 2 across warm mineral springs park

Charming cottage for 2 across warm mineral springs park
Warm Mineral Springs
9.0 out of 10, Wonderful, (29 reviews)
"We were enjoying our stay."
United States
Inna K.
The price is ￥7,033
￥21,669 total
includes taxes & fees
Oct 1 - Oct 2
Charming cottage for 2 across warm mineral springs park
Dining

7. Waterfront Pool Home Canal Front in Quiet Area

Waterfront Pool Home Canal Front in Quiet Area
New York Section
8.8 out of 10, Excellent, (20 reviews)
"Awesome host and beautiful home."
United States
cheryl b.
The price is ￥9,846
￥66,351 total
includes taxes & fees
Sep 21 - Sep 22
Waterfront Pool Home Canal Front in Quiet Area
TV

8. (B) Beautiful place to stay in Florida

(B) Beautiful place to stay in Florida
Port Charlotte
9.4 out of 10, Exceptional, (34 reviews)
"It was just what we were looking for. Comfortable and convenient. "
United States
Robert M.
The price is ￥11,721
￥38,039 total
includes taxes & fees
Sep 29 - Sep 30
(B) Beautiful place to stay in Florida
Dining

9. Charming & Cozy: Close to Beach & Shops ~ Parking!

Charming & Cozy: Close to Beach & Shops ~ Parking!
Port Charlotte
9.4 out of 10, Exceptional, (6 reviews)
"We had a nice stay"
United States
Laurie A.
The price is ￥11,877
￥35,788 total
includes taxes & fees
Oct 1 - Oct 2
Charming & Cozy: Close to Beach & Shops ~ Parking!
Outdoor pool, a heated pool

10. Heated SALT Pool - 3bd - Sunny

Heated SALT Pool - 3bd - Sunny
North Port
10.0 out of 10, Exceptional, (31 reviews)
"We loved our stay. We will be back next year. The place was clean and exceeded our expectations."
United States
KATHERINE
The price is ￥16,456
￥54,379 total
includes taxes & fees
Sep 18 - Sep 19
Heated SALT Pool - 3bd - Sunny
Terrace/patio

11. Rivers Edge Bungalow Waterside

Rivers Edge Bungalow Waterside
Warm Mineral Springs
10.0 out of 10, Exceptional, (1 review)
"It was a quiet place! Nice clean and comfortable inside. The water scenery around the property was beautiful! Tarpon swimming around! Alligators swimming around! 20-30 minutes from Venice beaches! All in all was a great spot for a weekend getaway! And its also pet friendly which is great!"
United States
Chris C.
The price is ￥12,346
￥32,244 total
includes taxes & fees
Sep 28 - Sep 29
Rivers Edge Bungalow Waterside
Coffee/tea maker, fridge, microwave, oven

12. Perfect 4-bedroom house with AC in peaceful Port Charlotte

Perfect 4-bedroom house with AC in peaceful Port Charlotte
Port Charlotte
9.8 out of 10, Exceptional, (7 reviews)
"Such a great host! So many amenities we were blown away! Recommend staying at this vrbo! Easy access to many places! "
United States
Kim P.
The price is ￥20,316
￥47,884 total
includes taxes & fees
Sep 24 - Sep 25
Perfect 4-bedroom house with AC in peaceful Port Charlotte
Dining

13. Burnt Store Isles Golf Home, W/Hot Tub/King Bed/Fast WIFI/Unbeatable Location

Burnt Store Isles Golf Home, W/Hot Tub/King Bed/Fast WIFI/Unbeatable Location
Burnt Store Isles
10.0 out of 10, Exceptional, (22 reviews)
"Wonderful location. Very clean and well laid out house. "
United States
Yvonne T.
The price is ￥23,442
￥58,918 total
includes taxes & fees
Sep 23 - Sep 24
Burnt Store Isles Golf Home, W/Hot Tub/King Bed/Fast WIFI/Unbeatable Location
TV, offices

14. Newly Renovated - Modern Apartment - 2 of 4

Newly Renovated - Modern Apartment - 2 of 4
Punta Gorda
9.6 out of 10, Exceptional, (19 reviews)
"Cute, modern and very clean apartment! The apartment had all the conveniences of home which is just what we needed for our short stay! Though it is located near a major road, it is very quiet and car traffic was minimal and could not be heard inside the apartment. Highly recommend! We will return!"
United States
Andrea
The price is ￥15,472
￥36,237 total
includes taxes & fees
Sep 19 - Sep 20
Newly Renovated - Modern Apartment - 2 of 4
Sun loungers

15. Charming 2-bedroom house in Englewood with WiFi and AC

Charming 2-bedroom house in Englewood with WiFi and AC
Englewood South
10.0 out of 10, Exceptional, (5 reviews)
"Cute, clean, comfortable beds. Perfect for our needs."
United States
Sharon K.
The price is ￥11,721
￥38,039 total
includes taxes & fees
Sep 18 - Sep 19
Charming 2-bedroom house in Englewood with WiFi and AC
Beach nearby, sun loungers, beach towels

16. Water Front Boundary Vacation Home Villa close to beaches, golfing, Fishing

Water Front Boundary Vacation Home Villa close to beaches, golfing, Fishing
Oakland Hills
9.8 out of 10, Exceptional, (78 reviews)
"Nice stay in good location"
United States
John W.
The price is ￥13,895
￥51,744 total
includes taxes & fees
Sep 30 - Oct 1
Water Front Boundary Vacation Home Villa close to beaches, golfing, Fishing
Coffee/tea maker, fridge, microwave, oven

17. 10 minutes to Mineral Springs w/large Pool and Pet Friendly!

10 minutes to Mineral Springs w/large Pool and Pet Friendly!
North Port
9.8 out of 10, Exceptional, (17 reviews)
"Very nice place"
United States
Rhonda W.
The price is ￥10,971
￥53,185 total
includes taxes & fees
Sep 21 - Sep 22
10 minutes to Mineral Springs w/large Pool and Pet Friendly!
Dining

18. Tropical Palm Oasis - Cozy Private Heated Pool Home!

Tropical Palm Oasis - Cozy Private Heated Pool Home!
Port Charlotte
8.8 out of 10, Excellent, (19 reviews)
"The home had plenty of room. Pool area was nice. So happy to be able to take our little dog with us."
United States
Shelia M.
The price is ￥9,846
￥65,882 total
includes taxes & fees
Sep 28 - Sep 29
Tropical Palm Oasis - Cozy Private Heated Pool Home!
Terrace/patio

19. 3/2 Heated Pool & Putting Green - Port Charlotte - Come Relax & Enjoy!

3/2 Heated Pool & Putting Green - Port Charlotte - Come Relax & Enjoy!
Port Charlotte
10.0 out of 10, Exceptional, (13 reviews)
"Lovely home, quiet neighborhood and conveniently located to Punta Gorda!"
United States
Tonia F.
The price is ￥22,504
￥60,336 total
includes taxes & fees
Sep 22 - Sep 23
3/2 Heated Pool & Putting Green - Port Charlotte - Come Relax & Enjoy!
Children's area

20. Luxury Place - 23017, one block away from Bayshore Park. 3/4 ml of Punta Gorda.

Luxury Place - 23017, one block away from Bayshore Park. 3/4 ml of Punta Gorda.
Port Charlotte
9.4 out of 10, Exceptional, (26 reviews)
"Great stay."
United States
Rebecca A.
The price is ￥12,659
￥45,121 total
includes taxes & fees
Sep 18 - Sep 19
Luxury Place - 23017, one block away from Bayshore Park. 3/4 ml of Punta Gorda.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top DeSoto County Hotel Reviews

Wyvern Hotel, an Ascend Collection Hotel

Wyvern Hotel, an Ascend Collection Hotel

10/10 Excellent
"Another stay at this extraordinary hotel. The rooms are exquisite and I love the piano bar. Conveniently located downtown near to bridge and all of the restaurants. Live local and this is my new favorite lovers getaway hotel!!"
Angela 1-night trip
Posted 5 hours ago
Wyvern Hotel, an Ascend Collection Hotel

Find out more about DeSoto County

Vacation Apartments in DeSoto County

Search for Vacation rentals in DeSoto County on Expedia! You can easily find your home rentals, villas, Vacation apartments in DeSoto County using one of the methods below:

  • View our selection of featured Vacation rentals in DeSoto County
  • Use the map to find apartments and other Vacation homes in the DeSoto County neighbourhood you prefer
  • Enter your travel dates to view the best deals on Vacation rentals in DeSoto County while they last

Look no further and take a look at our great range of rental properties in DeSoto County!