The Best Resorts & Hotels with Spas in Central Mississippi, MS from ￥10,370 in 2026 | Expedia

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Check availability on Central Mississippi Resorts & Hotels with Spas

Tonight

Sep 22 - Sep 23

Tomorrow

Sep 23 - Sep 24

This weekend

Sep 25 - Sep 27

Next weekend

Our top choices for Central Mississippi hotels with a spa

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A spacious hotel lobby with multiple seating areas, including tables and chairs, and a reception desk.

A bathroom with a granite countertop sink, a mirror, a toilet, and a towel rack with towels.

A compact living space with a kitchenette, a red sofa, a coffee table, and a large mirror.

1. Best Western Plus Philadelphia-Choctaw Hotel and Suites

Philadelphia

￥18,215

￥20,036 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a bed, bedside table, lamp, and a large mirror.

A living room with a flat-screen TV, a sofa, a coffee table, a potted plant, and a window with curtains.

A clean, modern kitchen with a coffee station, a microwave, and a large window.

A lobby with two red patterned armchairs, a fireplace, a large mirror, and a staircase.

2. Baymont by Wyndham Philadelphia/Choctaw MS

Philadelphia

￥11,156

￥11,937 total

includes taxes & fees

Oct 19 - Oct 20

A brick building with a sign for "The Mason Boutique Hotel" and the number 915.

A hallway with framed architectural drawings, a wooden bench, and a dining area with a chandelier.

A spacious living room with a fireplace, a staircase, and a view of the outdoors.

A room with two upholstered chairs, a round table with a lamp, and a decorative wall piece.

3. The Mason Boutique Hotel

Louisville

￥23,440

￥25,549 total

includes taxes & fees

Oct 5 - Oct 6

A spacious lobby with a central floor design, seating arrangements, and a view into the dining area.

A hotel room with two beds, a wooden headboard, a red chair, and two framed pictures on the wall.

A hotel kitchen with a stainless steel sink, granite countertop, and wooden cabinets. There is a framed picture on the wall and a red chair in the background.

A spacious restaurant with high ceilings, multiple dining tables, and chairs. There are large windows providing natural light and a seating area with a sofa and a small table.

4. Drury Inn & Suites Meridian

Meridian

￥16,044

￥17,568 total

includes taxes & fees

Sep 27 - Sep 28

A spacious room with a large window, a sofa, a TV, and a table with a lamp.

A hotel room with a desk, chair, bed, and a TV.

A hotel room with a sofa, a desk with a computer, a flat-screen TV, a lamp, and a painting on the wall.

A restaurant with wooden chairs and tables, a refrigerator, and a large window with a view of greenery.

5. Econo Lodge Inn & Suites Philadelphia MS

Philadelphia

￥10,965

￥12,062 total

includes taxes & fees

Oct 12 - Oct 13

A lakeside deck with Adirondack chairs, a stone fire pit, and a view of the lake.

A row of white Adirondack chairs by a lake with a clear sky.

A spacious living area with a fireplace, comfortable seating, and a television.

A pathway leading to a building with a glass facade, surrounded by lush greenery and a body of water in the background.

6. Lake Tiak O Khata Resort

Louisville

￥12,825

￥13,980 total

includes taxes & fees

Sep 23 - Sep 24

A modern hotel entrance with a covered walkway, stone pillars, and a glass door entrance.

A hotel room with two beds, a bedside table with a phone and a small speaker, and a wall-mounted light fixture.

An outdoor patio area with multiple round tables and chairs, a stone wall, and a building with large windows in the background.

A modern dining area with tables and chairs, a coffee station, and large windows providing natural light.

7. Holiday Inn Express & Suites Meridian I 20 by IHG

Meridian

￥17,147

￥18,777 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and tables.

A modern kitchen with a central island, a buffet setup, and a clear view of the dining area.

A reception area with a large mural of a lake and trees, a reception desk, and several seating areas with artwork on the walls.

A modern hotel with a prominent 'La Quinta' sign, featuring a covered entrance and a landscaped area in front.

8. La Quinta Inn & Suites by Wyndham Meridian

Meridian

￥13,843

￥15,158 total

includes taxes & fees

Oct 4 - Oct 5

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Choose what matters most at spa hotels in Central Mississippi

Pool

Breakfast included

Hot tub

4 stars

5 stars

Top Central Mississippi Hotel Reviews

Drury Inn & Suites Meridian

Drury Inn & Suites Meridian

10/10 Excellent

"The hotel was very nice. A really nice thing was the buffet set up for happy hour. You could have dinner and drinks for free! We’re definitely going back."

Rodeway Inn West Point, MS

Rodeway Inn West Point, MS

10/10 Excellent

"They remodel looks great didn't stink like mildew very clean house keeping nice staff nice they put my whole family on first floor which was nice"

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