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Check prices for these dates

In two weeks
Mar 27 - Mar 29
In two months
May 8 - May 10
In three months
Jun 5 - Jun 7
In four months
Jul 3 - Jul 5

Our top choices for Byron vacation homes

Exterior

Vacation Home in Rochester

Magical Nest Hideaway
10.0 out of 10, Exceptional, (141 reviews)
"Great place to stay."
United States
Matthew S.
The price is ￥9,331
￥18,938 total
includes taxes & fees
Mar 14 - Mar 15
Magical Nest Hideaway
Fridge, microwave, oven, stovetop

Vacation Home in Kutzky Park

2 Blks St Marys Main Fl Beds Bath CoveredByFaith
10.0 out of 10, Exceptional, (101 reviews)
"Easy check in and host was very helpful "
United States
Joshua M.
The price is ￥13,127
￥39,043 total
includes taxes & fees
Mar 15 - Mar 16
2 Blks St Marys Main Fl Beds Bath CoveredByFaith
Fridge, microwave, oven, stovetop

Vacation Home in Rochester

Cheshire House // Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo Clinic
10.0 out of 10, Exceptional, (41 reviews)
"Great place to stay. Loved the fenced in yard for our dogs."
United States
Tara C.
The price is ￥24,293
￥68,388 total
includes taxes & fees
Mar 21 - Mar 22
Cheshire House // Family Home, Fenced Yard, Pet Friendly, 2 mi from Mayo Clinic
Interior

Vacation Home in Kutzky Park

4 blks St Marys Main fl beds/bath CoveredByFaith
9.8 out of 10, Exceptional, (59 reviews)
"We enjoyed our stay."
United States
Joseph V.
4 blks St Marys Main fl beds/bath CoveredByFaith
Microwave, oven, stovetop, dishwasher

Vacation Home in Slatterly Park

Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
10.0 out of 10, Exceptional, (17 reviews)
"This is a great property! Highly recommend!"
United States
Anne G.
The price is ￥28,548
￥37,419 total
includes taxes & fees
Mar 12 - Mar 13
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester
Smart TV, books

Vacation Home in Washington

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
9.8 out of 10, Exceptional, (23 reviews)
"Location was great, home was clean and well stocked. "
United States
Jessica T.
The price is ￥25,258
￥32,895 total
includes taxes & fees
Mar 27 - Mar 28
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Smart TV, books

Vacation Home in Slatterly Park

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
10.0 out of 10, Exceptional, (21 reviews)
"I love staying in their properties. I always know I am going to be comfortable and have a great stay. "
United States
Carissa W.
The price is ￥14,994
￥35,288 total
includes taxes & fees
Mar 12 - Mar 13
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic
Smart TV

Vacation Home in Kutzky Park

Kutzky Cottage // 3 BR, 4 Blocks to Mayo, Family & Pet Friendly, Fenced Yard
10.0 out of 10, Exceptional, (21 reviews)
"Perfect fenced in backyard for pets!"
United States
Kim A.
Kutzky Cottage // 3 BR, 4 Blocks to Mayo, Family & Pet Friendly, Fenced Yard
Exterior

Vacation Home in Folwell

3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
9.6 out of 10, Exceptional, (25 reviews)
"Very clean and ready for us to stay when we arrived."
United States
David L.
The price is ￥13,892
￥40,270 total
includes taxes & fees
Mar 12 - Mar 13
3 blk St Mary 11 Mayo Pet Friendly Covered ByFaith
3 bedrooms, desk, iron/ironing board, travel crib

Vacation Home in Rochester

Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
9.8 out of 10, Exceptional, (7 reviews)
"Nice place to stay, close to all the activities we wanted to do."
United States
Kimberly K.
Cozy 3BR near Mayo and downtown. Charming, spotless, and designed for comfort with restful bedrooms, a stocked kitchen, and two welcoming living spaces. Perfect for Mayo visits, business trips, or family stays. Dogs allowed, too.
Smart TV

Vacation Home in East Side Pioneers

The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry
9.4 out of 10, Exceptional, (13 reviews)
"Great place!"
United States
Jeremiah E.
The price is ￥17,271
￥41,006 total
includes taxes & fees
Mar 15 - Mar 16
The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry
Smart TV, fireplace, books

Vacation Home in East Side Pioneers

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
8.8 out of 10, Excellent, (28 reviews)
"Lovely place to stay, before or after surgery. John was so nice answering questions and even stopping over when we needed something silly. "
United States
Michelle L.
The price is ￥9,945
￥34,895 total
includes taxes & fees
Mar 17 - Mar 18
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Fridge, microwave, oven, stovetop

Vacation Home in Kutzky Park

Bluebird // Charming 2-bedroom, 1 bathroom house, 5 blocks to Mayo Clinic
10.0 out of 10, Exceptional, (7 reviews)
"Great location, quiet neighborhood and I loved the artwork!!!"
United States
Mary M.
Bluebird // Charming 2-bedroom, 1 bathroom house, 5 blocks to Mayo Clinic
Interior

Vacation Home in Rochester

Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
10.0 out of 10, Exceptional, (6 reviews)
"This property had everything we needed. Super cute and simple decor, comfortable beds and clean. We would stay here again!! "
United States
Anonymous traveler
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven
Property grounds

Vacation Home in Folwell

3 blks to St. Marys Pet Friendly CoveredByFaith
9.4 out of 10, Exceptional, (11 reviews)
"Hunting trip we had a blast. Home was very comfortable and perfect location. Will do same place next time in Rochester Thank you"
United States
Darren S.
3 blks to St. Marys Pet Friendly CoveredByFaith
Dining

Vacation Home in East Side Pioneers

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
8.8 out of 10, Excellent, (13 reviews)
"Great stay for a quick stop in Rochester. Clean, quiet neighborhood."
United States
Jill S.
The price is ￥10,676
￥30,501 total
includes taxes & fees
Mar 15 - Mar 16
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
Smart TV, DVD player, foosball, books

Vacation Home in Parkway

1 mile Mayo 2 step entry Encourage Covered ByFaith
10.0 out of 10, Exceptional, (1 review)
"Nice little place and close to the Mayo Clinic. It was perfect. "
United States
Philip
1 mile Mayo 2 step entry Encourage Covered ByFaith
Interior

Vacation Home in Kutzky Park

Hart House // One Bed, 1 Ba, St Mary's Mayo Clinic from the Front Porch
10.0 out of 10, Exceptional, (4 reviews)
"Fun neighborhood good bars and restaurants "
United States
David M.
The price is ￥10,798
￥32,968 total
includes taxes & fees
Mar 16 - Mar 17
Hart House // One Bed, 1 Ba, St Mary's Mayo Clinic from the Front Porch
Exterior detail

Vacation Home in Rochester

Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
10.0 out of 10, Exceptional, (1 review)
"This was a fantastic experience, far better than anticipated! Only a couple of comments: this high tech house was a little over the head of my crew and a guidebook to show us how to use all those remotes would have been most welcome. And one of my folks was looking for a can opener… We had a lovely time and the next convention we have in Rochester I will book here again without hesitation! "
United States
Patricia B.
The price is ￥56,147
￥73,927 total
includes taxes & fees
Mar 19 - Mar 20
Quiet 3 BDR Home- private sauna & skyline view- close to downtown & Mayo Clinic
Exterior

Vacation Home in Rochester

1st Luxury Residential Elevator rooftop deck
The price is ￥46,056
￥73,468 total
includes taxes & fees
Mar 12 - Mar 13
1st Luxury Residential Elevator rooftop deck
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Byron Hotel Reviews

Spark by Hilton Rochester South

Spark by Hilton Rochester South

10/10 Excellent
"Clean and nice"
Maria 5-night trip
Posted 1 hour ago
Spark by Hilton Rochester South

Find out more about Byron

Byron Vacation Homes information

Number of reviews
540
Accommodation
144 Vacation Homes
Lowest Price
￥18,938
Highest Price
￥73,927