Find 5 Star Hotels in Prague City Center from ￥12,333

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Prague City Center 5 Star Hotels

Our top choices for Prague City Center 5-star hotels

Reception
Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (3114)
"Great location, lovely hotel "
United Kingdom
Sally Louise
The price is ￥18,678
￥21,671 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Michelangelo Grand Hotel Prague
Premium bedding, minibar, in-room safe, desk
Almanac X Alcron Prague

Almanac X Alcron Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (826)
"Beautiful hotel. Amazing staff and lovely room. Really well placed for the city. "
United Kingdom
Louise
The price is ￥25,513
￥29,300 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Almanac X Alcron Prague
Lobby
Grandior Hotel Prague

Grandior Hotel Prague

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1205)
"Fabulous place to stay and within easy walking distance to shops and places of interest. "
United Kingdom
Mairi
The price is ￥16,193
￥18,884 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Grandior Hotel Prague
Front of property - evening/night
Grandium Hotel Prague

Grandium Hotel Prague

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1109)
"Great rooms, friendly staff, wonderful breakfast"
United States
Toni
The price is ￥17,812
￥20,696 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Grandium Hotel Prague
Exterior
Four Seasons Hotel Prague

Four Seasons Hotel Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (612)
"All perfect"
United States
Amos
The price is ￥105,190
￥118,538 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Four Seasons Hotel Prague
Deluxe Room, 1 King Bed, Balcony (Church View) | Premium bedding, pillowtop beds, free minibar items, in-room safe
ANDAZ PRAGUE, BY HYATT

ANDAZ PRAGUE, BY HYATT

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (172)
"Overall a great experience."
United Kingdom
Mark
The price is ￥42,439
￥48,279 total
includes taxes & fees
Jan 5 - Jan 6, 2026
ANDAZ PRAGUE, BY HYATT
Restaurant
Iron Gate Hotel & Suites Prague by BHG

Iron Gate Hotel & Suites Prague by BHG

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1000)
"Nice rooms, good staff"
Canada
Prasanna K.
The price is ￥20,176
￥23,348 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Iron Gate Hotel & Suites Prague by BHG
Lobby
Kosher Hotel KING DAVID Prague

Kosher Hotel KING DAVID Prague

5.0 star property
Prague City Center
8.2 out of 10, Very Good, (919)
"Lovely spacious rooms, great food. "
United States
Adena
The price is ￥26,378
￥30,290 total
includes taxes & fees
Dec 14 - Dec 15
Kosher Hotel KING DAVID Prague
City view
Grand Hotel Bohemia

Grand Hotel Bohemia

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1004)
"The location was fantastic. Breakfast was amazing. Everyone working at the hotel was pleasant and professional!"
United States
Richard
The price is ￥22,054
￥25,434 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Grand Hotel Bohemia
Restaurant
Falkensteiner Hotel Prague

Falkensteiner Hotel Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (422)
"Great hotel near main rail station"
United States
Alexander
The price is ￥23,785
￥27,379 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Falkensteiner Hotel Prague
Club Room, 1 King Bed | Premium bedding, minibar, in-room safe, desk
Prague Marriott Hotel

Prague Marriott Hotel

5.0 star property
Prague City Center
9.0 out of 10, Wonderful, (1001)
"Wonderful hotel, great location, everything was perfect."
United States
Michael
The price is ￥29,839
￥34,166 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Prague Marriott Hotel
Local cuisine
Cosmopolitan Hotel Prague

Cosmopolitan Hotel Prague

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1069)
"Great location and fantastic hotel "
United Kingdom
David
The price is ￥20,492
￥23,702 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Cosmopolitan Hotel Prague
Meeting facility
Hotel Kings Court

Hotel Kings Court

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1007)
"Amazing hotel and friendly staff "
Canada
Claire
Hotel Kings Court
Presidential Suite, 2 Bedrooms, Terrace, City View | Balcony view
The Grand Mark Prague - The Leading Hotels of the World

The Grand Mark Prague - The Leading Hotels of the World

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (735)
"The staff were extremely friendly and helpful. The breakfast was amazing - probably one of the best breakfast buffets I've ever had. The location was perfect - could walk to the Old Town in under 10 minutes, which was ideal for the Christmas Markets. The beds were comfortable and room was very quiet. If I ever go back to Prague then I'd 100% stay here again."
United Kingdom
Emily
The price is ￥42,698
￥47,822 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Grand Mark Prague - The Leading Hotels of the World
Breakfast, lunch and dinner served
Hilton Prague Old Town

Hilton Prague Old Town

5.0 star property
Prague City Center
8.8 out of 10, Excellent, (1000)
"Lovely hotel"
United Kingdom
ira
The price is ￥24,760
￥28,471 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hilton Prague Old Town
Exterior
The Mozart Prague by Accor

The Mozart Prague by Accor

5.0 star property
Prague City Center
9.2 out of 10, Wonderful, (1000)
"Amazing stay!!!"
United Kingdom
Aimee
The price is ￥38,619
￥43,993 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Mozart Prague by Accor
Exterior
Eurostars Thalia

Eurostars Thalia

5.0 star property
Prague City Center
8.8 out of 10, Excellent, (713)
"Clean room, friendly stuff, good food on breakfast."
United States
Leonid
The price is ￥10,345
￥12,333 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Eurostars Thalia
Meeting facility
Art Deco Imperial Hotel

Art Deco Imperial Hotel

5.0 star property
Prague City Center
9.6 out of 10, Exceptional, (1000)
"Room was spotless and the premises are amazing. "
United States
Susan
The price is ￥20,514
￥23,727 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Art Deco Imperial Hotel
Reception
The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts

5.0 star property
Prague City Center
9.4 out of 10, Exceptional, (1002)
"Amazing location right next to Old Town Square. The staff were very courteous and attentive as well. The Emblem was the perfect base camp for exploring Prague!"
United States
Sean
The price is ￥36,434
￥41,554 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Emblem Prague Hotel - Preferred Hotels & Resorts
Meeting facility
Ambassador Zlatá husa

Ambassador Zlatá husa

5.0 star property
Prague City Center
8.2 out of 10, Very Good, (751)
"This hotel is lovely, perfect location. All the attractions restaurants bars are all in walking distance, would definitely stay here again ."
United Kingdom
Catherine
The price is ￥15,433
￥18,036 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Ambassador Zlatá husa
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Prague City Center.
K+K Hotel Central Prague

K+K Hotel Central Prague

Hybernska 10 Prague
The price is ￥18,509 per night from Jan 6 to Jan 7
￥18,509
￥21,481 total
Jan 6 - Jan 7, 2026
includes taxes & fees
9.2/10 Wonderful! (1,039 reviews)
Still don't see what you're looking for?
See all properties in Prague City Center.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Prague City Center Hotel Reviews

Michelangelo Grand Hotel Prague

Michelangelo Grand Hotel Prague

10/10 Excellent
"Lovely hotel in a great location. Breakfast was excellent, rooms were clean and comfortable. "
Karen 3-night trip
Posted 6 hours ago
Michelangelo Grand Hotel Prague

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Prague City Center?
The amount you pay for a 5-star hotel in Prague City Center can vary according to when you decide to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to land the best rate on a luxurious stay.

  • Search for the lowest price per night from ￥16,250

What makes a hotel 5 stars in Prague City Center?
From gourmet dining venues and 24-hour gyms to swimming pools and deluxe bedding, the 5-star experience in Prague City Center is all about comfort and indulgence. But it calls for more than just top-notch amenities to receive a 5-star rating. Accommodations also have to offer extraordinary services like in-room massages, dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Prague City Center?
Our filters are the quickest way to narrow down what you're looking for. Select "5-star" and "All inclusive" to show the finest properties in Prague City Center where your lodging, meals, activities and entertainment are included in the upfront price. At these retreats, your vacation is pure relaxation and indulgence from the moment you arrive.

Explore a world of travel with Expedia