Bridge of the Americas (Puente de las Americas). Once known as Thatcher Ferry Bridge, near an industrial shipping zone in Panama close to the the Panama Canal.

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Check availability on Panama Canal Zone 5 Star Hotels

Our top choices for Panama Canal Zone 5-star hotels

Outdoor pool, sun loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,605 reviews)
"Great Location, good food."
United States
Yohan
The price is ￥24,896
￥27,385 total
includes taxes & fees
Jun 29 - Jun 30
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
"yes, nice breakfast"
United States
Fernando
The price is ￥44,126
￥48,539 total
includes taxes & fees
Jun 26 - Jun 27
Waldorf Astoria Panama
Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (668 reviews)
"Beautiful hotel, excellent options for food and drinks within the hotel and nearby, and the staff was very attentive and helpful"
United States
Gabriel
The price is ￥46,978
￥51,676 total
includes taxes & fees
Jul 13 - Jul 14
Sofitel Legend Casco Viejo, Panama City
Restaurant

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
"Very clean nice staff and convenient"
United States
Ruth P
The price is ￥39,992
￥43,991 total
includes taxes & fees
Jun 20 - Jun 21
W Panama
Outdoor pool, pool umbrellas

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (343 reviews)
"Great stay! We enjoyed the hospitality!"
United States
Craig
The price is ￥34,820
￥38,302 total
includes taxes & fees
Jul 5 - Jul 6
Hyatt Regency Panama City
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"Great hotel. Highly recommend"
United States
Robert
The price is ￥40,937
￥45,031 total
includes taxes & fees
Jul 11 - Jul 12
JW Marriott Panama
Outdoor pool

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice hotel in the heart of the city. Friendly staff and very nice rooms."
United States
Ashley
The price is ￥40,233
￥44,256 total
includes taxes & fees
Jul 18 - Jul 19
Hilton Panama
View from property

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (703 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
The price is ￥43,177
￥47,495 total
includes taxes & fees
Jul 9 - Jul 10
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (230 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is ￥20,372
￥22,409 total
includes taxes & fees
Jul 14 - Jul 15
Renaissance Panama City Hotel
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1,001 reviews)
"This is an excellent hotel and would highly recommend."
United States
Shernon
The price is ￥31,656
￥34,821 total
includes taxes & fees
Jun 30 - Jul 1
The Westin Playa Bonita Panama
Couples treatment rooms, sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,000 reviews)
"Great Hotel and location, the staff was very friendly, we enjoyed our stay."
United States
Rafael
The price is ￥36,105
￥39,716 total
includes taxes & fees
Jul 17 - Jul 18
Bristol Panama, a Registry Collection Hotel
View from property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very Good, (1,000 reviews)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Lobby

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1,000 reviews)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
The price is ￥21,843 per night from Jun 28 to Jun 29
￥21,843
￥25,087 total
Jun 28 - Jun 29
includes taxes & fees
8.6/10 Excellent! (2,617 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—natural beauty, golf courses, and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
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Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

8/10 Good
"Everything was OK, just no sleeper and tooth brush in the room. We request late checout was not accepted."
Ali 2-night trip
Posted 4 hours ago
Hotel Riu Plaza Panama
W Panama

W Panama

10/10 Excellent
"I will be back the the room was so clean and the bed so comfy that I always look forward to my nap. I would recommend a little night life in the local area. The onsite driver Miguel gave a amazing tour of Panama the fresh juice in the lobby was delicious. The staff had so much ideas an recommendations. Ty Eduardo the bose speaker in the room made getting dress easy the breakfast buffet was fresh no flies nothing the Bar amazing bartenders. For me I will be back period."
Jasmine 5-night trip
Posted 1 day ago
W Panama

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on things like when you plan to go and the length of your vacation. Our insider tip for bagging an awesome deal? Use our pricing filters to compare all of the available accommodations for your selected dates.

  • Search for the lowest price per night from ￥15,723

What makes a hotel 5 stars in Panama Canal Zone?
In Panama Canal Zone, a hotel must offer a specific number of upscale features to earn 5 stars. These may include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their exceptional standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Expedia's filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most luxurious hotels in Panama Canal Zone where your meals, room, entertainment and activities are included in the price. At these getaways, your vacation is pure extravagance from the moment you check in.