Find 4 Star Hotels in Southeastern Indiana from ￥14,604

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeastern Indiana 4 Star Hotels

Our top choices for Southeastern Indiana 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,087 reviews)
"Rooms were clean and staff were friendly! "
United States
Amy
The price is ￥24,540
￥28,874 total
includes taxes & fees
Feb 18 - Feb 19
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,777 reviews)
"Amazing stay! "
United States
Erin
The price is ￥30,419
￥35,791 total
includes taxes & fees
Mar 19 - Mar 20
Omni Louisville Hotel
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,162 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ￥18,695
￥21,996 total
includes taxes & fees
Mar 15 - Mar 16
Embassy Suites Louisville Downtown
Interior

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,194 reviews)
"Beautiful old hotel with a fantastic bar in the lobby"
United States
Karen
The Brown Hotel
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,041 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is ￥20,732
￥24,393 total
includes taxes & fees
Feb 26 - Feb 27
Hotel Genevieve part of JdV by Hyatt
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,006 reviews)
"Great room, super kind staff"
United States
Rachel
The price is ￥27,489
￥33,113 total
includes taxes & fees
Feb 19 - Feb 20
21c Museum Hotel Louisville
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,002 reviews)
"Everything was just excellent on the day I stayed."
United States
Peggy
The price is ￥22,114
￥26,019 total
includes taxes & fees
Feb 26 - Feb 27
Hyatt Regency Louisville
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,003 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is ￥56,514
￥66,495 total
includes taxes & fees
Mar 7 - Mar 8
The Grady
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is ￥31,566
￥37,141 total
includes taxes & fees
Mar 15 - Mar 16
Louisville Marriott Downtown
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (445 reviews)
"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "
United States
Carol
The price is ￥29,892
￥35,172 total
includes taxes & fees
Mar 8 - Mar 9
Hotel Distil, Autograph Collection
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (74 reviews)
"i love this place"
United States
THANH
The price is ￥29,528
￥34,743 total
includes taxes & fees
Feb 22 - Feb 23
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Exterior

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,003 reviews)
"The area was congested but the motel was good. "
United States
Byrd
The price is ￥22,618
￥26,612 total
includes taxes & fees
Mar 20 - Mar 21
Seelbach Hilton Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (121 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is ￥17,657
￥28,471 total
includes taxes & fees
Mar 17 - Mar 18
Stellar Suites
Property entrance

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (665 reviews)
"The room was fantastic. Great location. Breakfast was excellent!! Mimi, the innkeeper, was gracious and very helpful with restaurant recommendations. Truly enjoyed my stay. "
United States
Kimberly
The price is ￥12,923
￥14,604 total
includes taxes & fees
Feb 18 - Feb 19
The Pepin Mansion Historic B&B
Seasonal outdoor pool

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.0 out of 10, Very Good, (27 reviews)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is ￥10,596
￥30,124 total
includes taxes & fees
Mar 9 - Mar 10
CozySuites at Nulu
Exterior

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (46 reviews)
"room very good i love hotel ❤️"
United States
Kartar
The price is ￥25,953
￥29,327 total
includes taxes & fees
Feb 22 - Feb 23
stayAPT Suites Louisville North-Clarksville
32-inch Smart TV with cable channels

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1 review)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is ￥25,339
￥37,090 total
includes taxes & fees
Mar 2 - Mar 3
The Reserve on Main
Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Exterior

TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites
4.0 star property
Downtown Louisville
TWO Stunning Nulu CozySuites
Free daily full breakfast

Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North
4.5 star property
Jeffersonville
7.4 out of 10, Good, (944 reviews)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Southeastern Indiana

Live music, a scenic riverfront, and top sights like KFC Yum Center—discover it all in Southeastern Indiana.

See all hotels in Southeastern Indiana
Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people

Top Southeastern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You'll find an array of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a guest favorite in this city that offers concierge services and massage services. Another property that gets excellent reviews from travelers is Hyatt Regency Louisville. A swimming pool and concierge services help make it a top choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
Expedia can help you easily track down the ideal 4-star hotel for your vacation in Southeastern Indiana. Use our filter tool to fine-tune your search by things like price, amenities and hotel star rating and get access to fantastic deals in a few clicks.

  • Search for the lowest price from ￥14,604

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
If you decide to book a stay at a 4-star hotel in Southeastern Indiana, you'll usually find plenty of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket surroundings. Choose a 5-star hotel and you'll have access to a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star stay, but both are terrific options for luxury guests.