Find 4 Star Hotels in Lower Florida Keys, FL from ¥16,510
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Compare Lower Florida Keys 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Lower Florida Keys 4-star hotels

Hyatt Centric Key West Resort and Spa
Hyatt Centric Key West Resort and Spa
9.0 out of 10, Wonderful, (1018)
The price is ¥26,131
¥39,085 total
includes taxes & fees
Sep 11 - Sep 12

Oceans Edge Key West Resort, Hotel & Marina
Oceans Edge Key West Resort, Hotel & Marina
9.0 out of 10, Wonderful, (1718)
The price is ¥24,899
¥36,643 total
includes taxes & fees
Sep 7 - Sep 8

Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
8.6 out of 10, Excellent, (2734)
The price is ¥25,160
¥38,327 total
includes taxes & fees
Sep 18 - Sep 19

Blue Flamingo Resort Key West
Blue Flamingo Resort Key West
7.8 out of 10, Good, (1576)
The price is ¥17,541
¥28,084 total
includes taxes & fees
Sep 7 - Sep 8

Margaritaville Beach House Key West
Margaritaville Beach House Key West
8.8 out of 10, Excellent, (1775)
The price is ¥26,576
¥39,218 total
includes taxes & fees
Sep 18 - Sep 19

Parrot Key Hotel & Villas
Parrot Key Hotel & Villas
9.0 out of 10, Wonderful, (1072)
The price is ¥17,239
¥27,912 total
includes taxes & fees
Sep 15 - Sep 16

Pier House Resort & Spa
Pier House Resort & Spa
9.0 out of 10, Wonderful, (1004)

Casa Marina Key West, Curio Collection by Hilton
Casa Marina Key West, Curio Collection by Hilton
8.4 out of 10, Very Good, (326)
The price is ¥30,871
¥43,638 total
includes taxes & fees
Sep 16 - Sep 17
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Learn more about Lower Florida Keys
Check out popular sights like Duval Street as you discover the local area in Lower Florida Keys.

Top Lower Florida Keys Hotel Reviews
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Lower Florida Keys Hotels by Star Rating
Stay near popular Lower Florida Keys attractions
- Hotels near Duval Street
- Hotels near Southernmost Point
- Hotels near Smathers Beach
- Hotels near Florida Keys Beaches
- Hotels near South Beach
- Hotels near Ernest Hemingway Home and Museum
- Hotels near Fort Zachary Taylor Historic State Park
- Hotels near Harry S. Truman Little White House
- Hotels near Florida Keys National Marine Sanctuary
- Hotels near Florida Keys Eco - Discovery Center
- Hotels near Calusa Beach
- Hotels near Key West Naval Station
More Accommodation Types in Lower Florida Keys
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- Inns in Lower Florida Keys
Explore more hotels
- Waterfront Home
- Stunning Ocean Views! 2BR Waterfront Home w/ Dock in Gated Keys Community
- JUDY'S PLACE ~ 2 Bedroom, 1 Bathroom Home in Venture Out Community!
- Oceanside Paradise in the FL Keys Free Kayaks Bikes Wifi Outdoor BBQ Grill
- SEA SHELL COTTAGE, Sleeps 2 - Summer Vacation, Fishing & Lobster Season is Here!
- COCONUT TELEGRAPH ~ Waterfront 2 BR/2Ba in Cudjoe Key w/ Dockage & Parking!
- Private Secluded Ocean View & Pool Near Key West
- Old Florida Style, Dockage, Swimming Pool (shared), just 20 miles from Key West
- Ocean View 4/2 Estate with Private Pool 15 minutes from Key West
- Little Torch Cottages
- Atlantic View Luxury Villa with Pool
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