A coastal promenade with palm trees, a sandy path, a bench, a playground, and a hotel in the background.

Find 4 Star Hotels in La Serena from ￥11,235

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on La Serena 4 Star Hotels

Our top choices for La Serena 4-star hotels

Indoor spa tub

Enjoy Coquimbo

Enjoy Coquimbo
4.5 star property
Coquimbo
8.0 out of 10, Very Good, (281 reviews)
"Clean room,. ocean view, great breakfast "
United States
Mario
The price is ￥17,031
￥17,031 total
Aug 17 - Aug 18
Enjoy Coquimbo
Reception

Hotel y Cabañas Campanario

Hotel y Cabañas Campanario
4.0 star property
La Serena
8.4 out of 10, Very Good, (111 reviews)
"The staff was very helpful and friendly"
United States
VIRGINIA
The price is ￥11,235
￥11,235 total
Aug 9 - Aug 10
Hotel y Cabañas Campanario
Restaurant

Hotel Dorys de Lourdes

Hotel Dorys de Lourdes
4.0 star property
Paiguano
The price is ￥53,699
￥53,699 total
Aug 18 - Aug 19
Hotel Dorys de Lourdes
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

La Serena and related destinations

Elegant colonial architecture frames La Serena's Plaza de Armas, where you can visit the 19th-century cathedral and nearby archaeological museum. Spend evenings at Avenida del Mar beaches, then take day trips to Elqui Valley observatories or penguin colonies at Humboldt Penguin National Reserve.

See all hotels in La Serena
A lighthouse with a white and red exterior, a tall tower, and a base with multiple windows.

Top La Serena Hotel Reviews

Hotel y Cabañas Campanario

Hotel y Cabañas Campanario

10/10 Excellent
"The staff was very helpful and friendly"
VIRGINIA 5-night trip
Posted 2 months ago
Hotel y Cabañas Campanario

Frequently asked questions

What are the best 4-star hotels in La Serena?
Expedia guests love staying at Enjoy Coquimbo. From its handy amenities to its welcoming staff, every aspect of this 4-star hotel in La Serena is designed to provide a memorable vacation experience.
How much does it cost to stay in a 4-star hotel in La Serena?
We can help you easily locate the perfect 4-star hotel for your vacation in La Serena. Use our filter tool to fine-tune your search by things like price, conveniences and star rating and get access to awesome deals in a couple of clicks.

  • Search for the lowest price from ￥11,235

What's the difference between 5-star and 4-star hotels in La Serena?
Give yourself the luxury treatment during your La Serena vacation by choosing a 4-star hotel. As well as featuring upscale accommodations, these retreats are usually packed with amenities like bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your stay an even more lavish and special one. 24-hour front desk, elegant furnishings and world-class dining are a few of the first-rate conveniences and services you'll likely have access to.