Find 4 Star Hotels in Florida Keys from ¥41,242

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Check availability on Florida Keys 4 Star Hotels

Our top choices for Florida Keys 4-star hotels

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (1,017 reviews)
"Perfect for our family, staff was amazing and the property is beautiful"
United States
Kathryne
The price is ¥48,091
¥65,115 total
includes taxes & fees
May 25 - May 26
Hawks Cay Resort

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,065 reviews)
"Room view of beach and sunset was worth the stay"
United States
Keith
The price is ¥47,948
¥62,629 total
includes taxes & fees
Jun 3 - Jun 4
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.4 out of 10, Exceptional, (1,441 reviews)
"nice clean place nice room pool was great"
United States
Patrick
The price is ¥40,712
¥52,090 total
includes taxes & fees
Jun 3 - Jun 4
Reefhouse Resort & Marina

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,282 reviews)
"Great location, clean rooms & nice staff. "
United States
Robert
The price is ¥27,991
¥43,014 total
includes taxes & fees
May 26 - May 27
Amara Cay Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,014 reviews)
"The resort is truly a tropical paradise."
United States
TAXAID
The price is ¥29,228
¥43,519 total
includes taxes & fees
May 19 - May 20
Islander Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (194 reviews)
"Clean room, friendly staff, food was great and so much to do. "
United States
Monica Jane
The price is ¥41,286
¥57,942 total
includes taxes & fees
Jun 2 - Jun 3
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,002 reviews)
"Can recommend the location, good breakfast, nice restaurants"
Germany
Hanspeter
The price is ¥53,916
¥69,322 total
includes taxes & fees
Jun 3 - Jun 4
Playa Largo Resort & Spa, Autograph Collection

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,000 reviews)
"This place is a sanctuary I love this hotel and with my mom and my child the best Mother’s Day ever 😍👍"
United States
Yadaris
The price is ¥26,415
¥41,242 total
includes taxes & fees
May 25 - May 26
La Siesta Resort & Villas

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,165 reviews)
"So clean and well maintained! Beautiful resort! Highly recommend!"
Canada
Joanne
The price is ¥35,085
¥45,385 total
includes taxes & fees
May 21 - May 22
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,000 reviews)
"Beautiful Hotel"
United States
maybelis
The price is ¥42,320
¥57,838 total
includes taxes & fees
May 17 - May 18
Tranquility Bay Beachfront Hotel and Resort

Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
4.0 star property
Marathon
9.4 out of 10, Exceptional, (442 reviews)
"Amazing views, hospitality and food!"
United States
kevin
The price is ¥38,346
¥50,705 total
includes taxes & fees
May 15 - May 16
Grassy Flats Resort & Beach Club

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (202 reviews)
"We had a great stay."
United States
Elise
Villas At Hawks Cay Resort

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.6 out of 10, Exceptional, (75 reviews)
"What a wonderful venue for our last 2 nights in the Keys. This place is a hidden gem. The entire staff, especially Edith, the bartender, were fantastic."
United States
Michael
The price is ¥90,787
¥110,800 total
includes taxes & fees
May 14 - May 15
The Islands of Islamorada

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.2 out of 10, Wonderful, (29 reviews)
"Great location! "
United States
Ricardo
The Reef at Marathon, Florida Keys

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.5 star property
Marathon
10.0 out of 10, Exceptional, (3 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina

Waterfront Luxury Villa

Waterfront Luxury Villa
4.0 star property
Marathon Shores
Waterfront Luxury Villa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Top Florida Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favorite in this city that offers a tennis court and a sauna. Another stay that rates highly with travelers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from ¥53,887

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveler experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodations generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.