Cape Girardeau, MO

Travel Guide

Photo by Skyy
Photo by Skyy
Photo by Jessica King
Photo by Jessica King
Photo by Skyy
Photo by Skyy
Photo by Alice Burghart
Photo by Alice Burghart
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
The price is ￥15,552 per night from Jul 28 to Jul 29
￥15,552
￥17,545 total
Jul 28 - Jul 29
includes taxes & fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
9.2/10 Wonderful! (360 reviews)
"The beds were amazing! The room was big and everything was in perfect condition. Will def recommend to other and will be back myself."

Reviewed on Jul 23, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is ￥13,291 per night from Jul 31 to Aug 1
￥13,291
￥14,992 total
Jul 31 - Aug 1
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,011 reviews)
"Excellent staff, amenities, cleanliness, and free breakfast. Property is well lit and visible from windows. The property is near the highway so you do hear trucks and motor cyclists unfortunately, but I would stay again if passing through as it seemed much better than nearby options and hotels."

Reviewed on Jul 22, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
The price is ￥10,337 per night from Jul 28 to Jul 29
￥10,337
￥11,662 total
Jul 28 - Jul 29
includes taxes & fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,004 reviews)
"Good for the quick trip I booked"

Reviewed on Jul 18, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
See all 161 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau
Book a stay at this family-friendly vacation home in Cape Girardeau. Enjoy a water park, a garden, and patios. Popular attractions eDen Spa & Salon and The Glenn ...
10/10 Exceptional! (136 reviews)
Comfortable & Clean
"Great Location short walking distance to the Downtown Area with lots do do, Restaurants, Water Park, Shopping. This is the 2nd time I have stayed and it is a true delight. Very spacious and comfortable. Easy to communicate with the Owner/Manager. I will be staying there again in the future. I recommend ..."

Reviewed on Jul 1, 2025

Serenity South -- Gardens, River-Views, and Refreshing Space
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

Cape Girardeau
Book a stay at this family-friendly apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and ...
8.6/10 Excellent! (16 reviews)
Great location
"This Vrbo was very spacious. It was clean and walkable to everything in Cape. The only thing I’ll say that affected sleep quality was the noise coming from the street. The windows are so thin and you can hear cars all night long. Bring your sound machine. Other than that, amazing."

Reviewed on Jun 15, 2025

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a garden, and in-room jetted tubs. Popular attractions eDen Spa & Salon and Riverfront Park are located ...
9.6/10 Exceptional! (36 reviews)
Perfect for us!
"This property is easy to find, the location is so close to downtown. We both found the bed very comfy, the amenities were great. My husband met the downstairs neighbor and he was very nice. Oh and the water pressure in the shower was 100%!"

Reviewed on Jun 23, 2025

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
See all properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University

Isle Casino Cape Girardeau

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

Isle Casino Cape Girardeau

Riverfront Bridge Park

Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Bridge Park

Saint Francis Medical Center

Though Saint Francis Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Cape Girardeau while you are here.

Saint Francis Medical Center

Show Me Center

Catch an event at Show Me Center during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Show Me Center

Riverfront Park

Riverfront Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Park