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Check prices for these dates

Tonight
Feb 20 - Feb 21
Tomorrow
Feb 21 - Feb 22
This weekend
Feb 20 - Feb 22
Next weekend
Feb 27 - Mar 1

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Our top choices for Santa Cruz hotels

Exterior

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ￥3,722
￥4,031 total
Mar 10 - Mar 11
Surbackpackers
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (88 reviews)
"Amazing breakfast "
United States
Sergio
The price is ￥7,642
￥7,642 total
Feb 27 - Feb 28
Ibis Santa Cruz DE LA Sierra
Double Room, 1 Queen Bed | Premium bedding, down comforters, minibar, blackout drapes

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (105 reviews)
"Excelente Hotel "
Mexico
JACOB
Hotel G
Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (343 reviews)
"Awesome place "
Canada
John
The price is ￥15,034
￥15,034 total
Feb 27 - Feb 28
Sun Hotel
Junior Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (43 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ￥7,187
￥7,187 total
Feb 21 - Feb 22
HOTEL OSHO
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (12 reviews)
"Perfect hotel"
Turkey
Yener
The price is ￥8,475
￥8,475 total
Mar 21 - Mar 22
Equipetrol Suites Apart Hotel
Triple Room | Free WiFi

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (2 reviews)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is ￥5,944
￥5,944 total
Feb 27 - Feb 28
Hotel Las Américas
Reception

Urban Suites

Urban Suites
3.0 star property
Santa Cruz
The price is ￥8,210
￥8,210 total
Feb 27 - Feb 28
Urban Suites
Outdoor pool

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
The price is ￥8,507
￥8,507 total
Feb 27 - Feb 28
AMERICA APARTMENTS
Bar (on property)

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very Good, (90 reviews)
"Easy to access"
United States
Dorothy
The price is ￥7,226
￥7,226 total
Mar 21 - Mar 22
Terranova Suites
1 bedroom, in-room safe, desk, iron/ironing board

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz
Restaurant

Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
The price is ￥8,352
￥8,661 total
Feb 21 - Feb 22
Prince Hotel
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (263 reviews)
"Nice hotel "
United States
Narciso Lorenzo
The price is ￥11,384
￥11,384 total
Feb 27 - Feb 28
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (85 reviews)
"Good price, great hotel!"
United States
James
The price is ￥6,032
￥6,032 total
Feb 27 - Feb 28
Premium Suites Deluxe Aparthotel Equipetrol
Outdoor pool

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (80 reviews)
"Clean, well maintained and good customer service."
United States
Johnny
The price is ￥5,565
￥5,565 total
Feb 27 - Feb 28
Delfines Collection Hotel By Mercure
Daily buffet breakfast (USD 10 per person)

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (202 reviews)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol
View from property

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ￥9,691
￥9,691 total
Mar 21 - Mar 22
Hotel Continental Park
Standard Room, 2 Twin Beds | Premium bedding, minibar, in-room safe, desk

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (284 reviews)
"Awesome hotel "
Canada
John
Hotel LP Santa Cruz Centro
Front of property

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (53 reviews)
"Staff was very courteous. They went above & beyond. Location was great!"
United States
America
Chairú Eco Hotel
BBQ/picnic area

Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
The price is ￥14,694
￥14,694 total
Mar 22 - Mar 23
Casa Por Temporadas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Vacation Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (85 reviews)
"Good price, great hotel!"
Premium Suites Deluxe Aparthotel Equipetrol
See all vacation rentals
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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

4.4/5 (70 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
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San Lorenzo Cathedral featuring interior views and a church or cathedral

San Lorenzo Cathedral

4.5/5 (36 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

10/10 Excellent
"Clean rooms, friendly people who work there. Parking always a plus "
Jorge 1-night trip
Posted 1 day ago
Premium Suites Deluxe Aparthotel Equipetrol

More cheap stays in Santa Cruz

Apartamento confortable para 2 personas

Apartamento confortable para 2 personas

Santa Cruz de la Sierra Departamento de Santa Cruz
The price is ￥3,403 per night from Feb 24 to Feb 25
￥3,403
￥6,496 total
Feb 24 - Feb 25

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a favorite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Chairú Eco Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Jose Luis Noya and Cozy and independent. Downtown house JH.. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Urubo Suite - Hostel and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
HOTEL OSHO is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza 24 de Septiembre?
Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.
What about the best place to stay near Ventura Mall?
One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and Novotel Santa Cruz De La Sierra are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool, and free buffet breakfast. A couple of other options that offer an onsite pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness center, tennis courts, and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the best hotel for staying near Viru Viru International Airport (VVI)?
Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 286 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Cine Center, Guarani Nandereko Nomai Art and Culture Center, and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Arenal Park, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.