
Southeast Illinois Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
- Plan, book, travel with confidence
- Better togetherSave up to ¥109,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
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Top Luxury Southeast Illinois Hotels

Rodeway Inn Effingham North
1400 Thelma Keller Ave Effingham IL
Rodeway Inn Effingham North provides luxe lodging where you'll enjoy premium channels and more.

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
100 E Front St Metropolis IL
Indulge in a luxury vacation at Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination. Sought-after amenities at this hotel include a casino, a ...
8.4/10 Very Good! (1,002 reviews)
"Great!"
Reviewed on Nov 6, 2026

Days Inn by Wyndham Effingham
1602 Damron Court Effingham IL
Treat yourself to classy accommodations with a stay at Days Inn by Wyndham Effingham, where you'll enjoy amenities like premium channels and more. Sought-after ...
6.2/10 (1,003 reviews)
"Took a quick trip to see a friend who is ill. Stopped overnight in Effingham. Felt a warm welcome when walking in the door. Ram was especially helpful. On our way back home we stopped there again. Definitely recommend this motel!"
Reviewed on Nov 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
