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Top Luxury Southeast Wyoming Hotels

The Historic Plains Hotel

1600 Central Avenue Cheyenne WY

5 min drive from Cheyenne Frontier Days Old West Museum

Take a lavish vacation in Cheyenne. Popular amenities include an outdoor pool, an indoor pool, and a restaurant.

Love the historic setting. Loved looking at the historic decorations. Staff was friendly

Reviewed on Apr 10, 2020

Cheyenne Guest Inn

2512 W Lincolnway Cheyenne WY

7 min drive from Cheyenne Frontier Days Old West Museum

Choose luxury at Cheyenne Guest Inn, where you can enjoy amenities like plush bedding, premium channels, and more.

8.8/10 Excellent! (2,171 reviews)

Our room was clean & quiet even though it's right off the interstate, breakfast was just the right amount of options & fresh Staff was friendly, courteous, and knowledgeable. Just what our family needed after 17 hrs on the road. Thank you!

Reviewed on Jan 20, 2026

Royal Inn

440 East A Street Casper WY

4 hours drive from Cheyenne Frontier Days Old West Museum

Pamper yourself with a luxe vacation at Royal Inn.

6.2/10 (581 reviews)

Nice staff

Reviewed on Dec 11, 2025

See all 727 properties in Southeast Wyoming

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.