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Top Beach Southwest Houston Hotels

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

2712 Southwest Fwy Houston TX

4 min drive from MD Anderson Cancer Center

Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...

7.8/10 Good! (1,731 reviews)

"Very peaceful in the middle of where I needed to go loved that"

Reviewed on Oct 28, 2026

Hotel Vesper, Houston, a Tribute Portfolio Hotel

5160 Hidalgo St Houston TX

5 min drive from MD Anderson Cancer Center

Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our ...

8.8/10 Excellent! (1,000 reviews)

"Good will be back"

Reviewed on Oct 21, 2026

See all 1,313 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.