Southeast Minnesota Romantic Vacations 2026

Photo by Sara Crotts

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Top Romantic Southeast Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN

2 hours drive from Mayo Clinic

Enjoy a stay at this romantic bed & breakfast, featuring a garden and a terrace for couples to enjoy.

9.8/10 Exceptional! (536 reviews)

"We had an amazing time. The owner, Richard, was delightful. The house is beautiful and hospitality was top notch. Breakfast was great. Not a single negative thing I can think of from our visit!"

Reviewed on Aug 16, 2026

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN

2 hours drive from Mayo Clinic

If you and your special someone are ready for a getaway, you're sure to love the spa and garden at this historic hotel. You'll also appreciate the luxury bedding, ...

9.2/10 Wonderful! (1,016 reviews)

Couples like: full-service spa, bar

Travelers say...

"What a beautiful hotel a block from the Mississippi."

Reviewed on Aug 18, 2026

AmericInn by Wyndham Austin

1700 8th St NW Austin MN

2 hours drive from Mayo Clinic

Enjoy a stay at this romantic hotel, featuring a hot tub and a lobby fireplace for couples to enjoy.

See all 924 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.