Southeast Minnesota Romantic Vacations 2026

Photo by Sara Crotts

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Top Romantic Southeast Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN

2 hours drive from Mayo Clinic

Enjoy a stay at this romantic bed & breakfast, featuring a garden and a terrace for couples to enjoy.

9.8/10 Exceptional! (554 reviews)

"Staying at the Alexander Mansion was like stepping back in time to a unique era in Winona history. Our host is very knowledgeable, welcoming and gracious. We were very impressed by all the attention to detail, the delicious breakfast, the lovely rooms and all the special touches that made this an ..."

Reviewed on Sep 28, 2026

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN

2 hours drive from Mayo Clinic

If you and your special someone are ready for a getaway, you're sure to love the spa and garden at this historic hotel. You'll also appreciate the luxury bedding, ...

9.2/10 Wonderful! (1,000 reviews)

Couples like: full-service spa, bar

Travelers say...

"Beautiful historic building outfitted with modern amenities."

Reviewed on Sep 30, 2026

AmericInn by Wyndham Austin

1700 8th St NW Austin MN

2 hours drive from Mayo Clinic

Enjoy a stay at this romantic hotel, featuring a hot tub and a lobby fireplace for couples to enjoy.

See all 951 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.