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Top Luxury vacation packages in Southwest Houston

Price found within the past 48 hours. Click for updated prices.

Hilton Houston Plaza/Medical Center

Texas Medical Center

￥103,770

per person

Dec 20 - Dec 25

found 7 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Houston (IAH)

8.6/10 Excellent! (2,207 reviews)

The Royal Sonesta Houston Galleria

The Galleria

￥112,228

per person

Dec 20 - Dec 25

found 7 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Houston (IAH)

8.8/10 Excellent! (2,348 reviews)

The suite was nice but (1) The carpet was old, (2) the coffee maker did not have any where to plug it (3) the area around the elevator doors were dirty (4) valet took too long to bring your cars (5) one of the remot controls in the room did not work.

Reviewed on Nov 12, 2026

Hyatt Regency Houston/Galleria

Greater Uptown

￥127,853

per person

Dec 20 - Dec 25

found 7 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Houston (IAH)

9.2/10 Wonderful! (1,553 reviews)

Houston Marriott Medical Center/Museum District

Texas Medical Center

￥142,567

per person

Dec 20 - Dec 25

found 7 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Houston (IAH)

9/10 Wonderful! (1,001 reviews)

Location was best

Reviewed on Nov 8, 2026

The Westin Galleria Houston

The Galleria

￥161,628

per person

Dec 20 - Dec 25

found 7 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Houston (IAH)

9.2/10 Wonderful! (1,005 reviews)

After I returned home I had 2 charges of $100 each that I did not make!! Still trying to get it removed!

Reviewed on Nov 9, 2026

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5* Luxury vacations in Southwest Houston

Price found within the past 48 hours. Click for updated prices.

Houston Grand Hotel - River Oaks

The Galleria

￥141,184

per person

Dec 20 - Dec 25

found 7 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Houston (IAH)

9.2/10 Wonderful! (512 reviews)

Hotel was very clean and elegant

Reviewed on Nov 12, 2026

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Top Luxury Southwest Houston Hotels

Hotel Granduca Houston

1080 Uptown Park Blvd Houston TX

9 min drive from MD Anderson Cancer Center

Be treated to a luxury stay at Hotel Granduca Houston, where you can enjoy amenities like Champagne service, massage services, and more. Notable amenities include ...

9.2/10 Wonderful! (1,001 reviews)

"My wife and I had an incredible weekend!"

Reviewed on Nov 8, 2026

Houston Grand Hotel - River Oaks

1919 Briar Oaks Ln Houston TX

7 min drive from MD Anderson Cancer Center

Treat yourself to some luxurious accommodations at Houston Grand Hotel - River Oaks, where you can enjoy amenities like massage services, 24-hour room service, ...

9.2/10 Wonderful! (527 reviews)

"Hotel was very clean and elegant"

Reviewed on Nov 12, 2026

JW Marriott Houston by the Galleria

5150 Westheimer Rd Houston TX

6 min drive from MD Anderson Cancer Center

Discover luxurious lodging at JW Marriott Houston by the Galleria, where you can enjoy amenities like 24-hour room service, pillowtop beds, and more. Deluxe ...

8.8/10 Excellent! (1,001 reviews)

"Dated, Overpriced, and Disappointing — 3 Stars at Best As a frequent traveler who stays in hotels regularly, I found this property extremely disappointing. The hotel is dated, worn, and desperately needs a refresh. The check-in process was painfully slow, the breakfast was unappetizing, and the bed ..."

Reviewed on Nov 11, 2026

See all 1,297 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.