Isla Colon Adults Only Vacations
Book a Adults Only Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Adults Only vacation packages in Isla Colon
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Price was ￥147,206, price is now ￥101,392 per person
￥101,392
per person
May 22 - May 26
found 8 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (5,100 reviews)
Great place to stay, great staff, I had a good time in the hotel itself
Reviewed on Mar 27, 2026
Megapolis Hotel Panamá
San Francisco
Price was ￥180,724, price is now ￥122,342 per person
￥122,342
per person
May 22 - May 26
found 8 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
8.4/10 Very Good! (1,448 reviews)
Breakfast was great everything was very clean lots of restaurants near by
Reviewed on Mar 27, 2026
5* Adults Only vacations in Isla Colon
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Price was ￥147,206, price is now ￥101,392 per person
￥101,392
per person
May 22 - May 26
found 8 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (5,100 reviews)
Great place to stay, great staff, I had a good time in the hotel itself
Reviewed on Mar 27, 2026
4 Night Adults Only vacations in Isla Colon
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
Bella Vista
Price was ￥147,206, price is now ￥101,392 per person
￥101,392
per person
May 22 - May 26
found 8 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (5,100 reviews)
Great place to stay, great staff, I had a good time in the hotel itself
Reviewed on Mar 27, 2026
Megapolis Hotel Panamá
San Francisco
Price was ￥180,724, price is now ￥122,342 per person
￥122,342
per person
May 22 - May 26
found 8 hours ago
Roundtrip flight included
Medellín (MDE) to Panama City (PTY)
8.4/10 Very Good! (1,448 reviews)
Breakfast was great everything was very clean lots of restaurants near by
Reviewed on Mar 27, 2026
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
