
Uptown Vacations
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Where to stay in Uptown
Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown

Eastport
4 out of top 10 points of interest in this area
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Uptown Hotel Deals

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ¥17,637 per night from Aug 22 to Aug 23
¥17,637
¥20,799 total
Aug 22 - Aug 23
includes taxes & fees
8.4/10 Very Good! (3,948 reviews)
"Maybe im just use to staying at the Drury across the street. But too many " policies ". Make sure you allow plenty of time for them to get your car out of valet. Not kid friendly IMO. Clean hotel, spacious rooms. Very nice staff"
Reviewed on Aug 10, 2025

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ¥14,754 per night from Aug 17 to Aug 18
¥14,754
¥17,186 total
Aug 17 - Aug 18
includes taxes & fees
8.8/10 Excellent! (2,924 reviews)
"It was perfect. It was quiet. It was clean. Everything was amazing. They were even doing renovations and it didn’t affect anything."
Reviewed on Aug 10, 2025

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ¥17,784 per night from Sep 2 to Sep 3
¥17,784
¥20,795 total
Sep 2 - Sep 3
includes taxes & fees
9.4/10 Exceptional! (2,931 reviews)
"The staff was wonderful! They were very attentive even though they were extremely busy. The manager went above and beyond his duty to get us in our room since we had our dog with us."
Reviewed on Aug 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Uptown

World's Largest Catsup Bottle
Find out about the history of Collinsville when you spend time at World's Largest Catsup Bottle. Discover the top-notch restaurants and great live music in this walkable area.
Things to do

St Louis: City Museum General Admission Ticket
¥3,291
per adult
96% of travellers recommend

St. Louis Arch Walking Tour and Entrance Ticket
¥7,383
per adult
100% of travellers recommend

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
¥3,545
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.