Uptown Vacations
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Where to stay in Uptown
Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown
Eastport
4 out of top 10 points of interest in this area
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Uptown Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ￥21,874 per night from Oct 27 to Oct 28
￥21,874
￥25,577 total
Oct 27 - Oct 28
includes taxes & fees
9.4/10 Exceptional! (3,191 reviews)
10/10
Very clean hotel. Location made many things walkable. Desk staff were friendly and beyond helpful. We had a refrigerator that wasn’t keeping our drinks cold and maintenance arrived to fix it immediately despite it being 8pm. Loved the 5:30 free drinks and food offerings. 10/10 recommend, and we will ...
Reviewed on Oct 21, 2025
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ￥15,875 per night from Nov 2 to Nov 3
￥15,875
￥18,531 total
Nov 2 - Nov 3
includes taxes & fees
8.8/10 Excellent! (2,999 reviews)
We traveled 10 hours away for an event we were going to. Clayton Hotel Plaza gave us everything we needed for our 2 night stay! When we come back to St Louis, we will be selecting this hotel again!
Reviewed on Oct 19, 2025
Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ￥15,039 per night from Nov 23 to Nov 24
￥15,039
￥17,735 total
Nov 23 - Nov 24
includes taxes & fees
8.4/10 Very Good! (4,031 reviews)
Nice stay
The room I originally booked was not available, due to the hotel over booking. I was given a business class room at the same rate. I was unaware of the valet parking fee of $50. The staff was great and the hotel was nice and convenient for what I was in town for.
Reviewed on Oct 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Uptown
World's Largest Catsup Bottle
Find out about the history of Collinsville when you spend time at World's Largest Catsup Bottle. Discover the top-notch restaurants and great live music in this walkable area.
Things to do
Best of St. Louis Small Group Tour w/ Arch & River Cruise
￥25,397
per adult
84% of travellers recommend
St Louis Self-Guided Driving and Walking Audio Tour
￥2,553
per traveler
St. Louis Ghost Tour: Sinister Sins & Shadows
￥4,858
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.