Photo by Dean Moore

Find hotels near St. Lucie Medical Center, Port Saint Lucie from ¥10,547

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 2,299 hotels close to St. Lucie Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for St. Lucie Medical Center hotels

Holiday Inn Port St. Lucie by IHG

3.0 star property
7.0 out of 10, Good, (1005)
"The Hotel need some remodeling and cleaning "
The price is ¥13,737
¥15,386 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Port St. Lucie by IHG

Best Western Port St. Lucie

2.5 star property
8.6 out of 10, Excellent, (1007)
"It was very nice hotels "
The price is ¥13,292
¥14,887 total
includes taxes & fees
Oct 7 - Oct 8
Best Western Port St. Lucie

Old Colorado Inn

3.5 star property
9.8 out of 10, Exceptional, (670)
"Enjoyed the historic atmosphere. Comfortable bed, nice downtown, easy distance and access to beach. "
Old Colorado Inn

Hutchinson Shores Resort & Spa

4.0 star property
9.4 out of 10, Exceptional, (1009)
"Excellent experience , clean up to date rooms and wonderful restaurant on site "
The price is ¥35,894
¥46,818 total
includes taxes & fees
Oct 19 - Oct 20
Hutchinson Shores Resort & Spa

Vistana Beach Club

3.5 star property
9.2 out of 10, Wonderful, (113)
"Wonderful "
The price is ¥28,656
¥32,095 total
includes taxes & fees
Sep 29 - Sep 30
Vistana Beach Club

Hampton Inn & Suites Port St. Lucie, West

2.5 star property
8.8 out of 10, Excellent, (1008)
"Nice place"
The price is ¥13,746
¥15,395 total
includes taxes & fees
Sep 28 - Sep 29
Hampton Inn & Suites Port St. Lucie, West

Residence Inn by Marriott Port St. Lucie

3.0 star property
9.2 out of 10, Wonderful, (1005)
"Good location, some construction in area, breakfast was very good"
The price is ¥16,248
¥18,198 total
includes taxes & fees
Sep 28 - Sep 29
Residence Inn by Marriott Port St. Lucie

The Lucie

3.0 star property
8.8 out of 10, Excellent, (1011)
"All staff were wonderfully friendly and accommodating!"
The price is ¥26,187
¥35,129 total
includes taxes & fees
Oct 23 - Oct 24
The Lucie

Tru by Hilton Port St. Lucie Tradition

2.5 star property
9.2 out of 10, Wonderful, (664)
"Always great to stay at this location love it there "
The price is ¥13,183
¥14,765 total
includes taxes & fees
Sep 29 - Sep 30
Tru by Hilton Port St. Lucie Tradition

TownePlace Suites by Marriott Port St. Lucie I-95

3.0 star property
9.4 out of 10, Exceptional, (1009)
"Comfortable, spacious, friendly staff, great location"
The price is ¥16,824
¥18,842 total
includes taxes & fees
Sep 29 - Sep 30
TownePlace Suites by Marriott Port St. Lucie I-95

Days Inn by Wyndham Stuart

2.5 star property
6.6 out of 10, (1006)
" Great stay"
The price is ¥12,179
¥13,640 total
includes taxes & fees
Sep 28 - Sep 29
Days Inn by Wyndham Stuart

Best Western Downtown Stuart

3.0 star property
8.6 out of 10, Excellent, (1009)
"The room and hotel were incredibly clean. The staff was so friendly, welcoming and attentive. I would definitely recommend this hotel to anyone. "
The price is ¥13,247
¥14,837 total
includes taxes & fees
Sep 29 - Sep 30
Best Western Downtown Stuart

SpringHill Suites Port St. Lucie

3.0 star property
8.6 out of 10, Excellent, (1002)
"Great location easy access to shopping, restaurants and the interstate."
The price is ¥15,214
¥17,039 total
includes taxes & fees
Sep 28 - Sep 29
SpringHill Suites Port St. Lucie

Courtyard by Marriott Port St. Lucie Tradition

3.0 star property
9.4 out of 10, Exceptional, (458)
"I would definitely stay there again!"
The price is ¥17,134
¥19,191 total
includes taxes & fees
Oct 13 - Oct 14
Courtyard by Marriott Port St. Lucie Tradition

Days Inn & Suites by Wyndham Fort Pierce Midtown

2.0 star property
6.6 out of 10, (1008)
"Staff is very helpful "
The price is ¥9,417
¥10,547 total
includes taxes & fees
Sep 28 - Sep 29
Days Inn & Suites by Wyndham Fort Pierce Midtown

Holiday Inn Express & Suites Port St. Lucie West by IHG

2.5 star property
8.6 out of 10, Excellent, (1004)
"Really nice stay for the price and breakfast was good "
The price is ¥16,718
¥18,724 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express & Suites Port St. Lucie West by IHG

Hilton Garden Inn at PGA Village / Port St. Lucie

3.0 star property
8.8 out of 10, Excellent, (1005)
"Enjoyed the stay"
The price is ¥15,035
¥16,839 total
includes taxes & fees
Sep 29 - Sep 30
Hilton Garden Inn at PGA Village / Port St. Lucie

Comfort Suites Stuart - Hutchinson Island

3.0 star property
9.6 out of 10, Exceptional, (1007)
"Very nice hotel"
The price is ¥18,235
¥20,423 total
includes taxes & fees
Sep 29 - Sep 30
Comfort Suites Stuart - Hutchinson Island

Mainstay Suites at PGA Village

2.5 star property
6.4 out of 10, (770)
"Very nice place to stay."
The price is ¥13,161
¥14,740 total
includes taxes & fees
Oct 1 - Oct 2
Mainstay Suites at PGA Village

Sheraton PGA Vacation Resort, Port St. Lucie

3.5 star property
9.0 out of 10, Wonderful, (640)
"Great property and location"
The price is ¥16,544
¥18,529 total
includes taxes & fees
Sep 29 - Sep 30
Sheraton PGA Vacation Resort, Port St. Lucie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Lucie Medical Center Hotel Reviews

Frequently asked questions

What's the area like around St. Lucie Medical Center?

St. Lucie Medical Center is located in Port Saint Lucie. This culturally rich area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 19 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to St. Lucie Medical Center?

Holiday Inn Port St. Lucie by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.6 mi (1 km) from St. Lucie Medical Center. Another good option is Best Western Port St. Lucie, located 2.7 mi (4.3 km) away.

How many hotels are there close to St. Lucie Medical Center?

Expedia has 19 hotels and other accommodations within a mile from St. Lucie Medical Center.

If I need to cancel the hotel reservation for my stay near St. Lucie Medical Center, will I receive a refund?

Yes, you'll find most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the top deals on offer near St. Lucie Medical Center.

Where can I learn more about changing or cancelling my trip in the area near St. Lucie Medical Center?

To access more information about picking new dates or cancelling your stay near St. Lucie Medical Center, go to https://www.expedia.com/service/.

What can I see and do near St. Lucie Medical Center?

Local parks like Port St. Lucie Botanical Gardens, River Park Marina, and Veterans Memorial Park are peaceful spots to stop and take in some fresh air. Dip your toes in the water at Normandy Beach, Fort Pierce Beach, and Herman's Bay Beach. Spend some time exploring the great outdoors at Walton Scrub Preserve, Ocean Bay Beachside, and Spruce Bluff Preserve.