Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Small Group Tour With Arch & River Cruise
Downtown St. Louis Smartphone Guided Audio Walking Tour App
Penrose Hotel Deals
Clayton Plaza Hotel & Extended Stay
Amazing breakfast, great staff. The breakfast was superbly run. Customized omelettes. Enjoyed the updated moen shower.
Reviewed on Apr 4, 2026
Drury Plaza Hotel St. Louis at the Arch
Clean roon
Reviewed on Apr 4, 2026
Pear Tree Inn St. Louis Near Union Station
Breakfast was ok...didnt go in the hot tub
Reviewed on Apr 4, 2026
21C Museum Hotel St Louis
This hotel took me by surprise with how fancy it was! The museum was so cool, the room was very upscale, and the restaurant and cafe were so good! Friendly staff and overall a great experience. My only gripe is that they didn’t have stairs easily accessible as an alternative to the elevators. One ...
Reviewed on Apr 4, 2026
Hyatt Regency St. Louis at The Arch
Everything prefect
Reviewed on Apr 4, 2026
Hollywood Casino & Hotel St. Louis
room very clean pretty plain for a suite very spacious and comfortable
Reviewed on Apr 1, 2026
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
