Southern Region Vacations & Trips

Book a Hotel + Flight or Car together to unlock savings

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  • Plan, book, travel with confidence

  • Better together

    Save up to ￥109,000 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Top destinations in Southern Region

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Blantyre

Blantyre

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

Protea Hotel by Marriott Blantyre Ryalls

4.5 out of 5
2 Hannover Avenue Blantyre
Fully refundableReserve now, pay when you stay
The price is ￥23,577 per night from Jun 12 to Jun 13
￥23,577
￥27,939 total
Jun 12 - Jun 13
includes taxes & fees
8.8/10 Excellent! (149 reviews)
"Everything about this hotel is great except for internet connectivity. It is not the best for business travel where you are likely to have virtually meetings while at the hotel. IT is very helpful in providing an individual router upon request which is an improvement but does not always provide uninterrupted ..."

Reviewed on Mar 30, 2026

Protea Hotel by Marriott Blantyre Ryalls
Amaryllis Hotel

Amaryllis Hotel

5 out of 5
2 Laws Rd Blantyre Southern Region
Fully refundableReserve now, pay when you stay
The price is ￥23,108 per night from May 23 to May 24
￥23,108
￥27,383 total
May 23 - May 24
includes taxes & fees
7.6/10 Good! (4 reviews)
"Not great but not a lot of other options around"

Reviewed on Dec 11, 2025

Amaryllis Hotel
Casa Mia

Casa Mia

3 out of 5
Kabula Hill Road Blantyre
The price is ￥15,510 per night from May 19 to May 20
￥15,510
￥18,438 total
May 19 - May 20
includes taxes & fees
8.6/10 Excellent! (127 reviews)
"The room was basic, but clean and comfortable. The mosquito net was in great condition. The restaurant steak is delicious, and the included breakfast (and espresso machine!) was excellent. My only gripe is that the staff seemed not to understand how things worked -- every question I asked had to ..."

Reviewed on Apr 14, 2026

Casa Mia
See all 105 properties in Southern Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southern Region vacation package cost?
Choose from any combination of flights, hotels and car rentals, and you can be vacationing in Southern Region from just . And the more you bundle, the more cash you save. Your dream vacation has never been so affordable.
How do I get a cheap travel package to Southern Region?
Our Southern Region vacation packages mean plenty of savings for the savvy traveler. For the best deals, simply bundle your flights, hotels and extras (such as activities) into one neat package. But low prices are just the beginning of your next big adventure. Book with Expedia and and you'll have over 550 air carriers and 1,000,000 hotel options all over the world to choose from. Whatever your budget or style, there's a vacation package to suit you.
What are the top hotels in Southern Region?
When it comes to properties in Blantyre, Protea Hotel by Marriott Blantyre Ryalls and Malawi Sun Hotel & Conference Centre are two fantastic options. If you're also spending time in Mangochi, Casa Mia and Hotel Victoria will make you feel at home.
How far in advance should I book my Southern Region vacation?
It's always wise to book early. Air carriers usually advertise flight tickets up to 12 months ahead of departure, and this is an ideal opportunity to pick up some of the lowest prices. Just been told you need to take all your vacation days in a few weeks? Don't fret. Expedia are never short of fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Southern Region travel package include?
Choose from a combination of hotels, flights and rental cars. Once you've made your booking, you can add experiences and tours. Want to pick your airfare class? That's easily done too. The choice is all yours when it comes to organizing your ideal Southern Region getaway.
What should I know before booking a Southern Region travel package?
A package can be easier on the bank balance than individually booking all you need for your trip. For example, bundle your hotels, flights and rental cars and score impressive savings. Whatever your vacation goals are, you're bound to find a package that matches your budget.
Can I choose my airline with a Southern Region Expedia vacation package?
You can. We offer more than 550 airline partners around the world, so fly with the carrier that suits your needs.
If I'm not able to travel, can I cancel my Southern Region vacation package?
If your travel plans in Southern Region have been upended, it's good to know that it's possible to cancel your booking. If you made your booking less than 24 hours ago, you may be able to receive a refund. If your booking is older than that, your airline, hotel or car rental company may impose fees. For more details, visit our Customer Service Portal.

Discover the most popular places to visit in Southern Region

Liwonde National Park

Explore the great outdoors at Liwonde National Park, a lovely green space in Liwonde.

Liwonde National Park

What to do in Southern Region

Ephraim, your tour guide, with guests

Guided Malawi Tour of Blantyre

￥15,690
per adult
Guided Malawi Tour of Blantyre
Finished Product! Some of the food you can make!

Malawian Cooking Class with Experienced Local Chef

￥3,971
per adult
Malawian Cooking Class with Experienced Local Chef
Hikers try climbing a rock on a tour

Zomba plateau Day Hike Tour

￥25,104
per adult
Zomba plateau Day Hike Tour
See all activities in Southern Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.