Top Hotels in Santee, NE from ￥18,049

Compare 53 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

"The house was over the top perfect for our family. It was spacious, everyone had their own space when they needed it. The kitchen/dining area was large enough for everyone to be in the kitchen at the same time helping cook. The property is near a river and the hike there and back was just what we needed for a workout. Golf cart was available to quick trips to the river. Peaceful and quiet surroundings. Already have reservations for next year"

"Extremely clean. Nice and quiet. All the amenities you could want."

"Beautiful historical home. Enough room for everyone. Would definitely recommend. Having lived in the area previously we found more than enough things to do.."

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"Great place!!"

"Beautiful place and a great view of the river. We will most likely be back next year"

"This property is in a great location! It is clean and well stocked with the essentials! The check in and communication was great! I would stay there again."

Microwave, dishwasher, coffee/tea maker, cookware/dishes/utensils

More cheap stays in Santee

Lewis and Clark Resort

43496 Shore Drive, Yankton, SD

￥18,049

per night

May 22 - May 23

8.6/10 Excellent! (158 reviews)

Stay near popular Santee attractions

Niobrara State Park

Take photos of the iconic old railroad bridge and camp in the cabins at the confluence of the Niobrara and Missouri rivers.

See properties

Santee hotels information

Number of reviews	158
Accommodation	53 hotels
Lowest Price	￥18,049
Highest Price	￥18,049

Frequently asked questions

Where is the best place for a stay in Santee?

Lewis and Clark Resort, located 16.8 mi (27 km) from the heart of Santee, is a top choice for your stay based on our traveler data. 1916 renovated 8 bedroom, family-friendly home with great views is another good choice for your stay in the area. See all available top hotels, or vacation rentals in Santee.

What are some of the best vacation rentals that Santee has to offer?

Bear Historic Home: You might like this vacation home rental near Santee. It is located on a river and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

Where can I learn more about changing or cancelling my trip to Santee?

For more information about rescheduling or cancelling your trip to Santee, click here.

What are some hotels with pools in Santee?

Lewis and Clark Resort: Features free parking, an outdoor pool, and free WiFi. View all hotels with pools in Santee.

What is staying in Santee like?

Those traveling to Santee are sure to enjoy the sights to see and things to do. There are 52 hotels and other accommodations in the surrounding area. Find out more about Santee.

What are the top places to visit in Santee?

A favorite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Check out what more to see and do in Expedia's Santee guide.

What's the weather like in Santee?

The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Santee are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.

Recent reviews of Santee hotels
Expedia verified reviews

Shady Creek Cabin - Family Friendly Getaway Near Lake

5/5 Excellent

Nice and beautiful cabin surround by tall trees

"We’ve enjoyed our stay at Shady Creek property for 4 days. We came from California for my nephews graduation at Mount Marty University. It was quiet, peaceful, and very nice and clean. We saw wild turkeys every morning and a family of deer every afternoons while we were there. Our teens for to do marshmallow s’mores over the nice big fire pit."

A verified traveler stayed at Shady Creek Cabin - Family Friendly Getaway Near Lake

Posted 12 days ago

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Find hotels in Santee, NE from ￥18,049

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Compare 53 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Spacious, Scenic Wagner Haven w/ River Access

The Copper Lodge in Springfield

Bear Historic Home

Private updated hunting lodge/farmhouse

Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha

Cottage on Verdigris Creek

Running Water Lodge with great amenities

On the Bluff, Overlooking the River. Outdoorsman’s Paradise!