Santa Isabel Vacation Rentals

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Check prices for these dates

In two weeks
Feb 6 - Feb 8
In two months
Mar 20 - Mar 22
In three months
Apr 17 - Apr 19
In four months
May 15 - May 17

Our top choices for Santa Isabel vacation rentals

Outdoor dining

Cottage in Palenque

Caribbean getaway: beach cottage just on the sand
10.0 out of 10, Exceptional, (1 review)
"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "
United States
Beth N.
The price is ￥37,515
￥46,690 total
includes taxes & fees
Jan 21 - Jan 22
Caribbean getaway: beach cottage just on the sand
Beach nearby, beach towels

Houseboat in Guna Yala

Exclusive sailboat for 2 people all inclusive in San Blas islands
10.0 out of 10, Exceptional, (1 review)
"Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!"
United States
Grazia B.
The price is ￥83,841
￥95,705 total
includes taxes & fees
Jan 26 - Jan 27
Exclusive sailboat for 2 people all inclusive in San Blas islands
Beach

Houseboat in Guna Yala Comarca

Catamaran experience in paradise
The price is ￥91,696
￥188,343 total
includes taxes & fees
Jan 31 - Feb 1
Catamaran experience in paradise
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10/10 Excellent
"This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful host, Leticia, who went above and beyond helpful. "
Dennis Or Trish H. 6-night trip
Posted 3 weeks ago
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Find out more about Santa Isabel

Search for holiday rentals in Santa Isabel on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Isabel using one of the methods below:

  • View our selection of featured holiday rentals in Santa Isabel
  • Use the map to find apartments and other holiday homes in the Santa Isabel neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Isabel while they last

Look no further and take a look at our great range of rental properties in Santa Isabel!

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, you can find vacation rentals near top attractions in Santa Isabel, or you can go with a more secluded option if you want a relaxing place to stay. Santa Isabel is known for its parks.

What are some of the best vacation rentals that Santa Isabel has to offer?

Caribbean Haven Of Nature 'Preci Beach': This vacation home rental outside of Santa Isabel is located on the beach and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation.

What’s there to see and do in Santa Isabel?

While exploring the area, visit the sights like Chagres National Park, Porvenir Museum, and Museum.

What’s a vacation rental in Santa Isabel like?

A vacation rental is a private property you can stay in for several days or longer in Santa Isabel. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for a family trip or a small group gathering.