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Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very Good, (1,832 reviews)
"This hotel is very clean and the Staff are very friendly."
United States
Doreen
The price is ¥17,358
¥19,094 total
includes taxes & fees
Jun 7 - Jun 8
Riande Aeropuerto Hotel & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (694 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is ¥36,788
¥40,468 total
includes taxes & fees
Jun 5 - Jun 6
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.2 out of 10, Wonderful, (290 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is ¥19,049
¥22,001 total
includes taxes & fees
May 19 - May 20
Arcadia Condo Suites

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very Good, (252 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is ¥12,321
¥13,553 total
includes taxes & fees
May 19 - May 20
MARINN Tropical Vibes Hotel

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,443 reviews)
"Great food, excellent service, overall beautiful hotel."
United States
derinique
The price is ¥21,849
¥24,034 total
includes taxes & fees
Jun 15 - Jun 16
Hotel Riu Plaza Panama

Modal

Modal
2.0 star property
Panama City
9.4 out of 10, Exceptional, (3 reviews)
"First of all, Expedia has it advertised as 10 minute walk or 3 minutes from airport. Far from the truth. 17km and 35 minutes 3 tolls away. No sign anywhere on the building and very dark at night. Our Uber driver could not find it neither. We finally got out and asked. Everything is modernized. Had to find the Email to find passcodes to enter. Found a women once we entered and wanted to know how we got in. 20 minutes later and in my junk mail. The building is new, everything clean. Everything!...
United States
Jose
The price is ¥11,549
¥12,740 total
includes taxes & fees
May 24 - May 25
Modal

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,147 reviews)
"great breakfast, great staff"
United States
Eduardo
The price is ¥16,393
¥18,033 total
includes taxes & fees
Jun 5 - Jun 6
Plaza Paitilla Inn Hotel

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,196 reviews)
"Clean room, very helpful staff and great breakfast."
United States
Emmanuela
The price is ¥16,461
¥18,107 total
includes taxes & fees
Jun 1 - Jun 2
Ramada Plaza by Wyndham Panama Punta Pacifica

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (432 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is ¥11,809
¥12,990 total
includes taxes & fees
May 25 - May 26
The Beach House

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,002 reviews)
"The staff were excellent!"
United States
James
The price is ¥21,287
¥23,415 total
includes taxes & fees
May 23 - May 24
Sheraton Grand Panama

Albrook Inn

Albrook Inn
3.0 star property
Panama City
7.8 out of 10, Good, (607 reviews)
"great place. nature is amazing."
United States
Linda
The price is ¥9,927
¥10,940 total
includes taxes & fees
May 22 - May 23
Albrook Inn

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,002 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
The price is ¥16,731
¥18,404 total
includes taxes & fees
Jun 7 - Jun 8
Courtyard by Marriott Panama Metromall

Serenade Lodging Rooms

Serenade Lodging Rooms
3.0 star property
San Francisco
8.4 out of 10, Very Good, (25 reviews)
"Nice affordable place. "
United States
Sandor
The price is ¥8,445
¥9,289 total
includes taxes & fees
May 18 - May 19
Serenade Lodging Rooms

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista
9.0 out of 10, Wonderful, (202 reviews)
"Amenities, staff, cleanliness, price all excellent!"
United States
Christopher
The price is ¥5,464
¥6,010 total
includes taxes & fees
May 18 - May 19
Panama House Bed & Breakfast

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice and safe place to stay"
United States
Nilesh
The price is ¥41,780
¥45,958 total
includes taxes & fees
Jun 5 - Jun 6
JW Marriott Panama

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,023 reviews)
"Excellent location, good parking."
United States
Mark
The price is ¥14,326
¥15,759 total
includes taxes & fees
May 20 - May 21
Radisson Hotel Panama Canal

Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania
9.0 out of 10, Wonderful, (712 reviews)
"The room was incredible, the staf all great, and the breakfast was delicious. Can't ask for much more. "
United States
Michael David
The price is ¥14,350
¥15,785 total
includes taxes & fees
Jun 6 - Jun 7
Best Western El Dorado Panama Hotel

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (653 reviews)
"Easily one the best hotel stays ever. Great property. Great food. Excellent service. "
United States
Jeremy
The price is ¥47,146
¥51,861 total
includes taxes & fees
Jun 1 - Jun 2
Sofitel Legend Casco Viejo, Panama City

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (214 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is ¥20,160
¥22,176 total
includes taxes & fees
May 23 - May 24
Renaissance Panama City Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1,109 reviews)
"It was a nice stay and breakfast is delicious"
United States
Susana
The price is ¥13,334
¥14,667 total
includes taxes & fees
Jun 9 - Jun 10
The Executive Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are The Executive Hotel and Principe Hotel and Suites. See all available top hotels, or vacation rentals in Santa Clara.
What's the top vacation rental in Santa Clara?
Oasis with pool near panama canal: This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1730 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.