Sanibel Isles Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas and neighborhoods for the activities you enjoy most. Learn more about Sanibel Isles
Sanibel Historical Museum and Village showing heritage elements

Mid Island

2 out of top 10 points of interest in this area

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

Find hotels in Mid Island

Sanibel Isles Hotel Deals

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is ￥25,298 per night from Jan 20 to Jan 21
￥25,298
￥31,740 total
Jan 20 - Jan 21
includes taxes & fees
9/10 Wonderful! (1,097 reviews)
Great location, fun atmosphere lots of fun amenities!

Reviewed on Jan 11, 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is ￥37,346 per night from Jan 25 to Jan 26
￥37,346
￥45,602 total
Jan 25 - Jan 26
includes taxes & fees
9/10 Wonderful! (1,525 reviews)
Staff was great. Room was clean

Reviewed on Jan 12, 2026

Sanibel Island Beach Resort
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is ￥60,053 per night from Jan 17 to Jan 18
￥60,053
￥70,920 total
Jan 17 - Jan 18
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
Our balcony had the best view of Sanibel Island and Harbour.

Reviewed on Jan 14, 2026

Marriott Sanibel Harbour Resort & Spa
See all 15,410 properties in Sanibel Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanibel Isles vacation package cost?
Discover the best of Sanibel Isles from as low as . We offer a great selection of rental cars, hotels and flights to suit your travel style. You can pick up even better deals when you add a few tours or experiences to your vacation package.
How do I get a cheap travel package to Sanibel Isles?
If you love landing a bargain, bundle your bookings into a Sanibel Isles vacation package. Whether you need hotels, flights, rental cars or activities, you can browse and book everything in one place. You'll have ample choice at your fingertips as well. Expedia has over 550 partner airlines and 1,000,000 hotels across the globe to select from. Fly with who you want, stay where you like and save your hard-earned money — now that's the ideal getaway!
Where should I stay in Sanibel Isles?
With interesting attractions like Sanibel Island Lighthouse and Sanibel and Captiva Island Visitors Center in this neighborhood, see if you can find a hotel near either of them. Sanibel Island Northern Beach is another sight in Sanibel Isles that people flock to.
What are the top hotels in Sanibel Isles?
When it comes to comfortable places to stay in Sanibel Isles, you can't beat Post Hurricane Update. Take a look at our offers and land a bargain.
How far in advance should I book my Sanibel Isles vacation?
Be rewarded with the biggest variety and the cheapest prices by booking your trip to Sanibel Isles nice and early. Air carriers typically sell flights around 12 months before departure, so secure your spot as soon as you can. That said, Expedia is committed to giving you the best deals around, so it's always a good time to book your dream vacation!
What does an Expedia Sanibel Isles travel package include?
It comes down to what sort of trip you're thinking about. Sanibel Isles travel deals can include flights, hotels and car rentals. You can mix and match to find the bundle that suits you. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Sanibel Isles travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, bundle your hotels, flights and rental cars and save a tidy sum. Whatever your vacation goals are, you're bound to find a package that's right for you.
Can I choose my airline with a Sanibel Isles Expedia vacation package?
Yes, the choice is yours. Expedia has access to more than 550 partner airlines across the globe, so you can tailor your Sanibel Isles escape according to your needs and budget.
If I'm not able to travel, can I cancel my Sanibel Isles vacation package?
You can. We totally understand that life happens, so we're here to help if you need to make changes to your Sanibel Isles vacation package. It may be possible to cancel or change your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may impose a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

Discover the most popular places to visit in Sanibel Isles

Bowman\'s Beach which includes general coastal views and a sandy beach

Bowman's Beach

Relax and revel in a visit to one of the area’s most beautiful beaches, great for swimming, fishing and finding special seashells.

Bowman's Beach

Things to do

Copacetic Day Sail

Copacetic Day Sail

￥10,960
per adult
100% of travellers recommend
Copacetic Day Sail
Fort Myers Beach Sunset and Dolphin Watching Cruise

Fort Myers Beach Sunset and Dolphin Watching Cruise

￥10,952
per adult
100% of travellers recommend
Fort Myers Beach Sunset and Dolphin Watching Cruise
Parasailing Adventure on Fort Myers Beach

Parasailing Adventure on Fort Myers Beach (400 Foot Flight)

￥16,377
per adult
94% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.