An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

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Check prices for these dates

This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

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Our top choices for San Antonio hotels

Exterior

1. Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (241 reviews)
"Very friendly staff and very helpful"
United States
Juan
The price is ￥18,975
￥18,975 total
Aug 23 - Aug 24
Alko Hotel Casa Nispero
Reception

2. San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (69 reviews)
"The location was excellent, within close distance to many good restaurants. The breakfast was good, with fruit and made to order eggs. The AC was quite adequate. "
United States
Jung
The price is ￥12,264
￥15,306 total
Sep 11 - Sep 12
San Antonio Hotel Boutique
Garden view

3. Casa Ruta Sur

Casa Ruta Sur
3.0 star property
San Antonio
9.8 out of 10, Exceptional, (31 reviews)
"Great location in Cali, close to everything. Friendly host and quiet place to rest."
United States
Arthur
The price is ￥12,067
￥12,067 total
Aug 25 - Aug 26
Casa Ruta Sur
Restaurant

4. Viajero Cali Hostel & Salsa School

Viajero Cali Hostel & Salsa School
2.0 star property
San Antonio
8.8 out of 10, Excellent, (65 reviews)
"Excellent stay. I stayed in a private room which was small, basic but comfortable. The staff were friendly. The hostel is in a excellent location close to restaurants, bars and attractions. The extra activities and the salsa school were amazing."
Australia
Jasmine
The price is ￥8,218
￥8,218 total
Aug 17 - Aug 18
Viajero Cali Hostel & Salsa School
Interior

5. Casa feliz

Casa feliz
1.0 star property
San Antonio
The price is ￥2,482
￥2,482 total
Sep 12 - Sep 13
Casa feliz
Interior

6. casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
4.0 out of 10, (2 reviews)
"Cheap and convenient location. But mosquitoes in room every night and leaky toilet. There are better options available. "
Australia
Meyer
The price is ￥2,580
￥3,217 total
Aug 18 - Aug 19
casa hostal ave maria san antonio cali
Full-size fridge, microwave, blender, cookware/dishes/utensils

7. Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is ￥3,551
￥3,551 total
Aug 26 - Aug 27
Epifania Guest House
Front of property

8. Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels
4.0 star property
El Peñon, 0.4 km from San Antonio
9.0 out of 10, Wonderful, (467 reviews)
"Good place to stay for a quick getaway! Close to restaurants and bars!"
United States
Manuel Alejandro
The price is ￥10,402
￥10,402 total
Aug 17 - Aug 18
Hotel el Peñón By Bithotels
Interior entrance

9. Hotel Dann Cali

Hotel Dann Cali
3.0 star property
El Peñon, 0.4 km from San Antonio
8.6 out of 10, Excellent, (603 reviews)
"Hotel is within walking distance to many attractions."
United States
Helen
The price is ￥13,757
￥13,757 total
Aug 22 - Aug 23
Hotel Dann Cali
In-room safe, blackout drapes, iron/ironing board, WiFi (free)

10. Cali River Suites

Cali River Suites
3.0 star property
Centenario, 0.5 km from San Antonio
9.2 out of 10, Wonderful, (141 reviews)
"Cali river suites is amazing! The suites make you feel like home. Clean, safe and affordable."
United States
Angelica
The price is ￥3,194
￥11,306 total
Aug 24 - Aug 25
Cali River Suites
Outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas, sun loungers

11. InterContinental Cali by IHG

InterContinental Cali by IHG
4.0 star property
El Peñon, 0.3 km from San Antonio
9.0 out of 10, Wonderful, (1,000 reviews)
"Very good hotel and staff"
United States
Pedro
The price is ￥20,387
￥20,387 total
Aug 16 - Aug 17
InterContinental Cali by IHG
Reception

12. Hotel Obelisco

Hotel Obelisco
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (541 reviews)
"Nice staff, the hotel has seen better days."
United States
Juan
The price is ￥10,560
￥10,560 total
Sep 13 - Sep 14
Hotel Obelisco
Front of property

13. Hotel Stein Colonial

Hotel Stein Colonial
3.0 star property
0.6 km from San Antonio
9.4 out of 10, Exceptional, (269 reviews)
"Super friendly staff, beautiful historic hotel, & great location/breakfast!"
United States
kevin
The price is ￥9,373
￥9,373 total
Sep 13 - Sep 14
Hotel Stein Colonial
Restaurant

14. NH Boulevard Del Río Cali

NH Boulevard Del Río Cali
3.5 star property
Centenario, 0.7 km from San Antonio
9.0 out of 10, Wonderful, (375 reviews)
"The hotel was beautiful, and the staff was incredibly welcoming, friendly, and helpful throughout our stay especially the girls at the front desk. The room is cozy and the sound proof was great, you can’t hear the cars outside. You’re close to the Boulevard, and “La Calle de Sabor” and cafe as well as restaurants. Overall, we had a wonderful experience and will definitely be back in the future!"
United States
Alvin
The price is ￥11,445
￥11,445 total
Aug 30 - Aug 31
NH Boulevard Del Río Cali
Exterior detail

15. Laundry House

Laundry House
2.0 star property
El Peñon, 0.3 km from San Antonio
The price is ￥2,833
￥2,833 total
Aug 18 - Aug 19
Laundry House
Front of property

16. HYPE STATES

HYPE STATES
3.5 star property
El Peñon, 0.6 km from San Antonio
9.4 out of 10, Exceptional, (57 reviews)
"Hi I’m so happy stay there for 6 days the place was very clean and the people so Nice thank you."
United States
carlos
The price is ￥13,415
￥13,415 total
Aug 14 - Aug 15
HYPE STATES
Rooftop terrace

17. Hampton by Hilton Cali, Colombia

Hampton by Hilton Cali, Colombia
4.0 star property
1.1 km from San Antonio
9.0 out of 10, Wonderful, (661 reviews)
"good location, nice views, pool n gym and very good breakfast!!"
United States
Howard
The price is ￥12,431
￥12,431 total
Aug 23 - Aug 24
Hampton by Hilton Cali, Colombia
Front of property

18. Altio hotel

Altio hotel
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (186 reviews)
"Very nice"
United States
Orlando
The price is ￥8,632
￥8,632 total
Aug 31 - Sep 1
Altio hotel
Interior

19. Hotel Dann Carlton Cali

Hotel Dann Carlton Cali
3.5 star property
El Peñon, 0.4 km from San Antonio
8.8 out of 10, Excellent, (479 reviews)
"Excellent all around"
United States
Kyle
The price is ￥17,674
￥17,674 total
Sep 4 - Sep 5
Hotel Dann Carlton Cali
Front of property

20. Now Hotel Cali - Adults Only

Now Hotel Cali - Adults Only
4.0 star property
1.1 km from San Antonio
8.8 out of 10, Excellent, (478 reviews)
"I love How friendly & knowledgable the staff was even thought there was a language barrier. I highly recommend this hotel !"
United States
deveena
The price is ￥13,974
￥13,974 total
Aug 15 - Aug 16
Now Hotel Cali - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Antonio

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Garden view
Casa Ruta Sur
3.0 star property
9.8
Exceptional
31 reviews
View
Exterior
Alko Hotel Casa Nispero
4.0 star property
9.4
Exceptional
241 reviews
View
Reception
San Antonio Hotel Boutique
3.0 star property
9.2
Wonderful
69 reviews
View
Restaurant
Viajero Cali Hostel & Salsa School
2.0 star property
8.8
Excellent
65 reviews
View
Interior
casa hostal ave maria san antonio cali
2.0 star property
4.0
2 reviews
View

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.
A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

When in El Peñon, you can plan a visit to Valle del Cauca Government Building and Sebastian de Belalcazar Statue and Viewpoint, some noteworthy sights in the nearby area.

Pance

Pance might not have many top sights, but Chorrera del Indio and Los Arrayanes Recreational Center are two attractions nearby that you can check out.

Rozo

Check out nearby sights like Fenix Air Museum while you're spending some time in Rozo and the surrounding area.

Top San Antonio Hotel Reviews

Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels

10/10 Excellent
"Excelente ubicación, limpieza, desayuno, personal con excelente actitud, sin duda regresaría al mismo Hotel si regreso a Calí."
Fredy 4-night trip
Posted 7 hours ago
Hotel el Peñón By Bithotels

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Another good option for your stay in the area is Viajero Cali Hostel & Salsa School.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.

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