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Check prices for these dates

Tonight
Mar 12 - Mar 13
Tomorrow
Mar 13 - Mar 14
This weekend
Mar 13 - Mar 15
Next weekend
Mar 20 - Mar 22

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,000 reviews)
"Attentive staff and excellent breakfast and amenities."
United States
Mario
The price is ￥15,023
￥16,923 total
Mar 14 - Mar 15
Wyndham Guayaquil Puerto Santa Ana
Rooftop terrace

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (47 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ￥10,314
￥10,473 total
Mar 16 - Mar 17
River View suites Puerto Santa Ana gye
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (104 reviews)
"The property was very clean and well maintained. Lots of security. The building is on the riverfront with many excellent restaurants within a few steps. Vibrant night life which was unfortunately very noisy when trying to sleep. Within walking distance to many attractions."
United States
Carolyn
The price is ￥17,573
￥17,732 total
Mar 23 - Mar 24
Luxury Suites Riverfront GYE
Terrace/patio

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
4.9 km from Puerto Santa Ana
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
The price is ￥2,518
￥2,518 total
Mar 13 - Mar 14
Villa Celeste - VC
Outdoor pool

Tropical Inn

Tropical Inn
2.0 star property
4.5 km from Puerto Santa Ana
8.0 out of 10, Very Good, (18 reviews)
"for the price was good"
United States
Rosa
Tropical Inn
Property entrance

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (606 reviews)
"Very close to the airport"
United States
Gian Piero
DC Suites Aeropuerto
Terrace/patio

Harmonie

Harmonie
2.0 star property
Simón Bolívar, 3.1 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (95 reviews)
"Friendly staff, great service! "
United States
Yerifer
The price is ￥4,769
￥4,769 total
Mar 13 - Mar 14
Harmonie
Exterior

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ￥7,631
￥7,631 total
Mar 13 - Mar 14
Hotel La Ria Durán
Classic Double Room | Free WiFi

Pachamac House

Pachamac House
2.0 star property
2.9 km from Puerto Santa Ana
The price is ￥3,100
￥3,100 total
Mar 20 - Mar 21
Pachamac House
Economy Triple Room | Free WiFi, bed sheets

Hotel Dorado

Hotel Dorado
2.0 star property
2.4 km from Puerto Santa Ana
8.8 out of 10, Excellent, (13 reviews)
"Great location! Great value "
United States
John
The price is ￥2,403
￥2,403 total
Apr 3 - Apr 4
Hotel Dorado
Terrace/patio

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (54 reviews)
"the property was ok for the price"
United States
ASONG
The price is ￥5,087
￥5,087 total
Mar 18 - Mar 19
Casa Serena
Suite, Jetted Tub | In-room safe, free WiFi, bed sheets

Hotel Varadero Internacional

Hotel Varadero Internacional
3.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
8.0 out of 10, Very Good, (67 reviews)
"Overall a good place to stay and close to most destinations."
United States
Daniel
Hotel Varadero Internacional
Superior Double Room | Private kitchen | Microwave, electric kettle, griddle, cookware/dishes/utensils

Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 3.5 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (12 reviews)
"You can walk to the airport."
United States
Digna
The price is ￥4,105
￥5,138 total
Mar 23 - Mar 24
Suitesecu Rentals Guayaquil
Down comforters, desk, free WiFi, bed sheets

Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
8.4 out of 10, Very Good, (108 reviews)
"Clean room, delicious breakfast, good location. "
United States
Miriam
Hotel Las Peñas
Lobby sitting area

Casa Veranda

Casa Veranda
2.5 star property
12.9 km from Puerto Santa Ana
Casa Veranda
Superior Double Room, 2 Twin Beds | Free WiFi, bed sheets

Hotel GH Sander

Hotel GH Sander
3.0 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.8 out of 10, Excellent, (16 reviews)
"great property. i would definitely come back again every time i come to guayaquil"
United States
George
Hotel GH Sander
Double Room, 1 Queen Bed, Private Bathroom, Ground Floor | Outdoor pool | Outdoor pool, sun loungers

MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
8.4 out of 10, Very Good, (168 reviews)
"Room was great and very clean. The staff is amazingly friendly and nice. This will be my go to hotel from now on ."
United States
Gary
MundialCity Hotel Guayaquil
Comfort Apartment, Kitchenette

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
The price is ￥6,359
￥6,359 total
Mar 13 - Mar 14
Guayacan Apart Hotel
Exterior

Hotel Savoy 1

Hotel Savoy 1
2.0 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
The price is ￥3,583
￥3,583 total
Apr 12 - Apr 13
Hotel Savoy 1
Living area

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
The price is ￥8,061
￥8,220 total
Apr 12 - Apr 13
NP Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

They are here because people started feeding them
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Central Market are some notable places to visit nearby.

Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Puerto Santa Ana Hotel Reviews

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

10/10 Excellent
"Superb service, transfers smooth, staff lovely, food lovely. . .all excellent!"
Susi 1-night trip
Posted 1 day ago
Holiday Inn Guayaquil Airport by IHG

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 83 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.