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Our top choices for Puerto Santa Ana hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,008 reviews)
"great safe place will be back "
United States
Tracy
The price is ¥17,259
¥19,378 total
Jun 6 - Jun 7
Wyndham Guayaquil Puerto Santa Ana

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (53 reviews)
"Very commensurate location and safe area"
United States
Luz
The price is ¥12,550
¥12,707 total
May 20 - May 21
River View suites Puerto Santa Ana gye

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
The price is ¥12,851
¥13,008 total
May 14 - May 15
Luxury Suites Riverfront GYE

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (625 reviews)
"Lovely, small, family run hotel. Nothing fancy but excellent price, clean and the staff is very helpful."
United States
Patricia
The price is ¥5,376
¥5,533 total
May 13 - May 14
DC Suites Aeropuerto

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
The price is ¥7,971
¥8,128 total
May 26 - May 27
NP Hotel & Suites

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
4.9 km from Puerto Santa Ana
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
The price is ¥2,075
¥2,075 total
Jun 2 - Jun 3
Villa Celeste - VC

Departamentos en la Garzota

Departamentos en la Garzota
4.5 star property
Garzota, 4 km from Puerto Santa Ana
The price is ¥4,504
¥4,740 total
May 20 - May 21
Departamentos en la Garzota

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ¥7,521
¥7,521 total
May 30 - May 31
Hotel La Ria Durán

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (254 reviews)
"Great stay and great staff!"
United States
Jemima
The price is ¥8,252
¥8,487 total
May 16 - May 17
Hotel Puerto Pacifico Guayaquil Airport

Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 3.5 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (12 reviews)
"Friendly and very responsive staff. Clean and well apportioned suite"
Ecuador
Jacques
The price is ¥3,640
¥4,662 total
May 25 - May 26
Suitesecu Rentals Guayaquil

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (56 reviews)
"Nice room, close to the airport. Was a bit noise at night because of the street dogs"
Australia
pavel
The price is ¥4,244
¥4,244 total
Jun 6 - Jun 7
Casa Serena

Tropical Inn

Tropical Inn
2.0 star property
4.5 km from Puerto Santa Ana
8.0 out of 10, Very Good, (18 reviews)
"for the price was good"
United States
Rosa
The price is ¥3,678
¥6,036 total
May 13 - May 14
Tropical Inn

Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.6 out of 10, Excellent, (39 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
The price is ¥4,002
¥4,159 total
May 13 - May 14
Hotel GH Alexander

Casa Veranda

Casa Veranda
2.5 star property
12.9 km from Puerto Santa Ana
The price is ¥4,506
¥4,506 total
May 25 - May 26
Casa Veranda

NCG Suite Samanes 3

NCG Suite Samanes 3
2.5 star property
8.1 km from Puerto Santa Ana
The price is ¥5,093
¥5,250 total
Jun 7 - Jun 8
NCG Suite Samanes 3

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (47 reviews)
"A lovely oasis in the city. Very relaxing and friendly service."
United States
Landy
The price is ¥8,873
¥9,950 total
May 24 - May 25
Iguanazu Bed & Breakfast

Hotel Varadero Internacional

Hotel Varadero Internacional
3.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
8.0 out of 10, Very Good, (70 reviews)
"Overall a good place to stay and close to most destinations."
United States
Daniel
The price is ¥4,244
¥4,401 total
May 16 - May 17
Hotel Varadero Internacional

Pachamac House

Pachamac House
2.0 star property
2.9 km from Puerto Santa Ana
The price is ¥3,003
¥3,003 total
May 20 - May 21
Pachamac House

MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
8.4 out of 10, Very Good, (172 reviews)
"We stay here anytime that we have a late arrival or early flight from Ecuador. They are always helpful when we are looking for something. There is a traditional Ecuadorian family type restaurant 100 feet from the hotel and several rental car agencies a couple of hundred meters from there. And naturally my daughter loves the pool. "
United States
Christopher
The price is ¥7,198
¥7,355 total
May 18 - May 19
MundialCity Hotel Guayaquil

Hotel Dorado

Hotel Dorado
2.0 star property
2.4 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (16 reviews)
"In the heart of Downtown (Centro) of Guayaquil, so may things are here and in walking distance, came by multiple times to drop off shopping. Place was spacious, had a mini fridge, a tv, as well as soap and shampoo. Was very comfortable, my only slight complaint is that the walls are pretty thin, you can hear the neighbors music and speaking, however, everything else was good and I'd stay here again in the future! Thank you Guayaquil 💜"
United States
Xochimilco
The price is ¥2,461
¥2,461 total
May 20 - May 21
Hotel Dorado
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Central Market are some notable places to visit nearby.

Top Puerto Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 84 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.