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Check prices for these dates

Tonight
Jan 25 - Jan 26
Tomorrow
Jan 26 - Jan 27
Next weekend
Jan 30 - Feb 1
In two weeks
Feb 6 - Feb 8

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,009 reviews)
"Clean rooms,great staff and very good food"
Canada
Abel Patricio
The price is ￥16,395
￥18,424 total
Feb 17 - Feb 18
Wyndham Guayaquil Puerto Santa Ana
Outdoor pool

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (46 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ￥12,471
￥12,627 total
Jan 26 - Jan 27
River View suites Puerto Santa Ana gye
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (103 reviews)
"The property was very clean and well maintained. Lots of security. The building is on the riverfront with many excellent restaurants within a few steps. Vibrant night life which was unfortunately very noisy when trying to sleep. Within walking distance to many attractions."
United States
Carolyn
The price is ￥16,255
￥16,411 total
Feb 8 - Feb 9
Luxury Suites Riverfront GYE
Children's activities

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice hotel with great breakfast and dining"
United States
Eulalia
The price is ￥13,235
￥14,947 total
Jan 26 - Jan 27
Oro Verde Guayaquil
Property entrance

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (594 reviews)
"Great location and clean hotel"
United States
Elvin
DC Suites Aeropuerto
Lobby

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.6 out of 10, Excellent, (836 reviews)
"Room was great and the check in excellent."
United States
Juan F
The price is ￥14,683
￥16,540 total
Feb 21 - Feb 22
Hilton Colon Guayaquil
Cafe

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,019 reviews)
"Excellent place to stay near the airport. Staff were polite, efficient. Room was spotless and great breakfast. "
Canada
Kelly
The price is ￥11,833
￥13,405 total
Feb 16 - Feb 17
Holiday Inn Guayaquil Airport by IHG
Reception

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,005 reviews)
"Good service , good breakfast."
United States
EULALIA
The price is ￥11,678
￥13,235 total
Jan 30 - Jan 31
TRYP by Wyndham Guayaquil Airport
Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers

Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,004 reviews)
"The breakfast was delicious, the staff were very friendly and helpful, everything was very clean, and the central location made it extremely convenient. Overall, a great stay!"
Mexico
Ana
The price is ￥12,573
￥14,065 total
Jan 30 - Jan 31
Grand Hotel Guayaquil, an Ascend Collection Hotel
Lobby lounge

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (136 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ￥9,248
￥10,329 total
Jan 26 - Jan 27
Mansión del Río
Rooftop pool

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (230 reviews)
"Very clean rooms and accommodating staff. I would stay here again."
United States
Hilda
Hotel Puerto Pacifico Guayaquil Airport
Daily buffet breakfast (USD 19 per person)

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (614 reviews)
"Very nice place to stay ! "
United States
Diana
The price is ￥14,013
￥15,804 total
Feb 1 - Feb 2
Sheraton Guayaquil Hotel
Property grounds

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (9 reviews)
"Wonderful hosts and felt like home "
United States
Tina
The price is ￥10,877
￥11,033 total
Jan 29 - Jan 30
Hostal Macaw
Free daily buffet breakfast

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,006 reviews)
"Great team and flawless check in. "
United States
Fabio
The price is ￥10,121
￥11,522 total
Feb 13 - Feb 14
Unipark by Oro Verde Hotels
Lobby

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (76 reviews)
"everything was great "
United States
Abraham
The price is ￥10,455
￥13,615 total
Feb 20 - Feb 21
Doubletree By Hilton Guayaquil
Terrace/patio

Harmonie

Harmonie
2.0 star property
Simón Bolívar, 3.1 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (89 reviews)
"Friendly staff, great service! "
United States
Yerifer
The price is ￥4,671
￥4,671 total
Jan 27 - Jan 28
Harmonie
Terrace/patio

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (108 reviews)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
The price is ￥52,806
￥58,087 total
Feb 6 - Feb 7
Hotel del Parque
Lobby

Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (919 reviews)
"We've stayed here several times and enjoyed it each time. It's a nice place and the front desk staff are very helpful. "
United States
Allison
The price is ￥9,585
￥10,777 total
Jan 30 - Jan 31
Hotel Palace Guayaquil
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,006 reviews)
"It was a good place to stay"
United States
Francisco
The price is ￥12,471
￥13,952 total
Feb 1 - Feb 2
Wyndham Garden Guayaquil
Outdoor pool, sun loungers

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (46 reviews)
"Excelente Todo "
Costa Rica
Cesar
The price is ￥8,928
￥9,995 total
Feb 1 - Feb 2
Iguanazu Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like San Francisco Square and Central Market while you're in town.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and San Francisco Square are some notable places to visit nearby.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Simón Bolívar

If you're spending some time in Simón Bolívar, Mall del Sol Shopping Center and Plaza del Sol are top sights worth seeing.

Top Puerto Santa Ana Hotel Reviews

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

10/10 Excellent
"Excellent place to stay near the airport. Staff were polite, efficient. Room was spotless and great breakfast. "
Kelly 1-night trip
Posted 2 days ago
Holiday Inn Guayaquil Airport by IHG

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Other good choices for your stay in the area include Luxury Suites Riverfront GYE and Administradora Condominio Guayaquil.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 83 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.