Panama Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

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    Better together

    Save up to ￥45,448 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Panama Vacation Packages

Panama Hotel Deals

Cobblestone Inn & Suites - Avoca

Cobblestone Inn & Suites - Avoca

2.5 out of 5
7013 N Chestnut St, Avoca, IA
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (631 reviews)
"Nice and clean"

Reviewed on Aug 21, 2025

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Cobblestone Inn & Suites - Avoca
Econo Lodge Inn & Suites

Econo Lodge Inn & Suites

2 out of 5
1614 Antique City Drivie, Walnut, IA
Fully refundableReserve now, pay when you stay
The price is ￥9,367 per night from Sep 6 to Sep 7
￥9,367
￥10,491 total
Sep 6 - Sep 7
includes taxes & fees
7.2/10 Good! (300 reviews)
"Host was very kind and helpful"

Reviewed on Aug 19, 2025

Econo Lodge Inn & Suites
Motel 6 Avoca, IA

Motel 6 Avoca, IA

2 out of 5
211 West Marty Drive, Exit 40 on I-80 and Highway 59, Avoca, IA
Fully refundableReserve now, pay when you stay
The price is ￥10,578 per night from Aug 26 to Aug 27
￥10,578
￥11,848 total
Aug 26 - Aug 27
includes taxes & fees
8/10 Very Good! (371 reviews)
"Nice hotel"

Reviewed on Aug 20, 2025

Motel 6 Avoca, IA
See all 18 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama vacation package cost?
You'll find cheap prices on Expedia for your Panama break. However, factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Panama costs.
What are the cheapest months to go to Panama?
If you're hoping to score a cheap Panama vacation package, consider planning a trip in January, February and November. You'll typically find lower prices on flights and hotels during these quieter months — ideal for a budget-friendly getaway.
How many days is enough for Panama?
The ideal duration for your Panama vacation depends on what you'd like to do and see. Generally, a handful of days to a week will give you time to visit all the leading attractions and discover some hidden gems along the way.
How to find the best Panama package deals?
Begin your search for a Panama package deal by entering your travel dates and destination under our "Packages" tab. Then add some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with big savings. If you don't find the perfect Panama package deal right away, just switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Panama escape underway.
Is it cheaper to book a Panama vacation as a package?
You can enjoy significant savings on your next Panama retreat by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to see some great flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Panama?
If you have your Panama vacation dates confirmed, book as soon as you can to grab some awesome deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for quick escapes.
How to plan a trip to Panama?

  1. Choose when to travel: Check your calendar and pack your bags. Your favorite season and the available activities will also help you decide when to visit Panama.
  2. Set a budget: Consider expenses like flights, food and transportation when calculating how much to save for your trip to Panama. Then, choose a property that fits your budget, whether that's a wallet-friendly stay or a lavish retreat.
  3. Decide how many days away: Start by making a list of all the attractions and activities you'd like to get to in Panama. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your bookings: With your travel dates in place, you can combine your car rental, hotels, flights and more into a personalized Panama vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.