Find Resorts & Hotels with Spas in Opelika, AL

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Check availability on Opelika Resorts & Hotels with Spas

Tonight
Dec 31 - Jan 1
Tomorrow
Jan 1 - Jan 2
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Opelika hotels with a spa

Exterior
Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG

Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG

Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG
2.5 star property
Opelika
8.6 out of 10, Excellent, (762)
"Great stay! "
United States
Ahmari
The price is ￥14,505
￥16,392 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG
Pool views, serves lunch and dinner
Auburn Marriott Opelika Resort & Spa at Grand National

Auburn Marriott Opelika Resort & Spa at Grand National

Auburn Marriott Opelika Resort & Spa at Grand National
3.5 star property
Opelika
9.2 out of 10, Wonderful, (369)
"Enjoyed my stay, beautiful resort, great staff, awesome spa services "
United States
Dr. LaQuanda
The price is ￥33,066
￥42,652 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Auburn Marriott Opelika Resort & Spa at Grand National
Spa reception
Laurel Hotel and Spa

Laurel Hotel and Spa

Laurel Hotel and Spa
5.0 star property
Auburn
10.0 out of 10, Exceptional, (1)
The price is ￥68,471
￥77,372 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Laurel Hotel and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Opelika Hotel Reviews

Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG

Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG

10/10 Excellent
"Clean room and bathroom, the staff was very helpful and nice. "
Spence 1-night trip
Posted 1 month ago
Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG
Auburn Marriott Opelika Resort & Spa at Grand National

Auburn Marriott Opelika Resort & Spa at Grand National

10/10 Excellent
"The porter was super friendly. Very nice stay. "
Michael 1-night trip
Posted 2 months ago
Auburn Marriott Opelika Resort & Spa at Grand National

Frequently asked questions

Looking for a spa hotel in Opelika?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the popular shops in Opelika. Be sure to pay a visit to the churches during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Opelika?
Holiday Inn Express Hotel and Suites of Opelika/Auburn by IHG is a highly recommended spa hotel with a fitness center. Another popular spa hotel in Opelika is Auburn Marriott Opelika Resort & Spa at Grand National.
How many spa hotels will I find in Opelika?
Among Expedia's 72 accommodation options in Opelika, there are 2 spa hotels.
What's there to see and do in Opelika?
Experience Opelika with a stop at John Emerald Distilling Company, RTJ Golf Trail at Grand National, and Museum of East Alabama. If you have extra time while you're in the area, you might want to stop by Railroad Avenue Historic District and Opelika Train Depot.
What is a Opelika spa hotel?
Spa hotels in Opelika provide lodging and have an on-site spa offering services such as facials as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.