The Best Hotels Closest to North Mississippi Medical Center in Tupelo for 2026

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Our top choices for North Mississippi Medical Center hotels

A modern lounge area with a neon sign, large windows, and a pool table.

A bar area with a large screen, bar stools, and a variety of bottles.

A modern hotel with a brick facade, large windows, and a covered outdoor seating area.

A modern interior with a brick wall, large windows, and a wooden floor.

1. Hotel Tupelo, a Wyndham Hotel

2.2 km from North Mississippi Medical Center

Doug

￥25,212

￥27,545 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

An outdoor seating area with wicker furniture and planters, a paved walkway, and a building with large windows.

A laundry area with two Whirlpool front-loading washers, a Tide detergent dispenser, and a sign indicating it's for guest use only.

A hotel dining area with multiple tables set for guests, featuring a carpeted floor and modern decor.

2. Holiday Inn Hotel & Suites Tupelo North by IHG

3 km from North Mississippi Medical Center

Larry

￥18,676

￥20,405 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a conference table, chairs, a bed, a TV, and a door leading to another room.

A covered patio with a table and chairs, a ceiling fan, and a stone building in the background.

A hotel room with a dark wood dining table, a brown leather chair, a microwave, a refrigerator, and a corkboard on the wall.

A hotel with a stone facade, multiple windows, and a parking lot with handicapped accessible spaces.

3. Candlewood Suites Tupelo North by IHG

3 km from North Mississippi Medical Center

Rhonda

￥16,618

￥18,156 total

includes taxes & fees

Sep 27 - Sep 28

A spacious lobby with a central reception desk, large potted plants, and a modern chandelier.

A spacious living room with a fireplace, comfortable seating, and a coffee table with fruit.

A spacious lobby with a fireplace, comfortable seating, and large windows offering views of the outside.

A modern lounge area with wicker furniture, a large wooden pendant light, and a colorful striped carpet.

4. Hilton Garden Inn Tupelo

2.3 km from North Mississippi Medical Center

Rhonda

￥16,742

￥18,291 total

includes taxes & fees

Oct 1 - Oct 2

A reception area with a wooden desk, a reception counter, a waiting area with brown upholstered chairs, a large window with a view of buildings, and a door marked "EXIT".

A compact kitchen with wooden cabinets, a microwave, a toaster, and a juice dispenser. There are two red chairs and a wooden table.

A hotel room with a green sofa, a desk with a computer and lamp, a small refrigerator, and a round mirror on the wall.

A hotel room with a desk, chair, television, minibar, and a bed.

5. SureStay Hotel by Best Western Tupelo North

2.8 km from North Mississippi Medical Center

Melissa

￥9,260

￥10,116 total

includes taxes & fees

Oct 4 - Oct 5

A hotel entrance with a covered waiting area, a bench, and a car parking lot.

A gym with exercise equipment, a fan, and a door leading to another room.

A reception desk with a laptop, a large decorative letter 'H', and a colorful striped wall in the background.

A staircase with carpeted steps and a black handrail, leading to a hallway with wooden walls and a tiled floor.

6. Studio 6 Suites Tupelo, MS - North

3.1 km from North Mississippi Medical Center

David

￥9,427

￥11,090 total

includes taxes & fees

Sep 26 - Sep 27

A hotel room with a bed, a desk with a flat-screen TV, a microwave, a sink, and a mirror.

A hotel lobby with a red chair, a table with stacked items, and a large window offering a view of the parking lot and trees.

A modern kitchen with a built-in stove, a coffee machine, and a refrigerator.

A reception area with a counter, a red chair, a small table with a lamp, and a view of the parking lot outside.

7. Motel 6 Tupelo, MS - Downtown

3 km from North Mississippi Medical Center

David

￥9,971

￥10,894 total

includes taxes & fees

Sep 27 - Sep 28

A room with a green wall, a decorative wall piece, an air conditioner, and a welcome sign.

A hotel room with two beds, a nightstand, a lamp, and two framed pictures on the wall.

A sign for Scottish Inns with a clear sky in the background.

8. Scottish Inns

2 km from North Mississippi Medical Center

David

￥9,496

￥10,374 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a chair, a television, and a window.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A hotel room with a blue sofa, a desk with a chair, a coffee table, and a kitchenette in the background.

A hotel fitness center with multiple treadmills, ellipticals, and a mirrored wall.

9. Holiday Inn Express Hotel & Suites Tupelo by IHG

4.1 km from North Mississippi Medical Center

Fernando

￥16,302

￥17,810 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a reception desk, seating area, and unique lighting fixtures.

A modern hotel building with a prominent 'tru by Hilton' sign, multiple windows, and a well-lit entrance.

A breakfast buffet area with various food items and a coffee machine.

A snack display in a store with various brands and types of snacks.

10. Tru By Hilton Tupelo

4.3 km from North Mississippi Medical Center

Justin

￥15,444

￥16,872 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with chairs and a fire pit, a brick building, and a clear sky.

An indoor swimming pool with clear blue water, surrounded by yellow and blue chairs, and a water fountain on the left.

A modern breakfast area with a counter, seating, and various food items.

A modern lounge area with a green sofa, red chairs, and a wooden table.

11. Home2 Suites By Hilton Tupelo, Ms

4.3 km from North Mississippi Medical Center

Michael

￥18,251

￥19,939 total

includes taxes & fees

Oct 11 - Oct 12

A spacious hotel lobby with a dining area, sofas, and a TV mounted on the wall.

A Comfort Suites hotel with a modern facade, a covered entrance, and a landscaped area in front.

A reception area with a stone wall, wooden reception desk, and a vending machine.

A hotel room with a wooden desk, a blue sofa, a small ottoman, a chair, a lamp, and framed pictures on the wall.

12. Comfort Suites North Tupelo

6.8 km from North Mississippi Medical Center

Peggy

￥13,970

￥15,262 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with a reception desk, seating area with ottomans, and a patterned carpet.

A multi-story hotel with a covered entrance and a parking area.

An indoor swimming pool with a clear view of the pool area, including the poolside seating and the pool's edge.

A kitchen with granite countertops, wooden cabinets, and a tiled backsplash.

13. Best Western Plus Tupelo Inn & Suites

6.3 km from North Mississippi Medical Center

Robert

￥16,435

￥17,955 total

includes taxes & fees

Sep 27 - Sep 28

A modern, well-lit office space with multiple tables and chairs, a reception area, and large windows offering a view of greenery.

A hotel room with a bed, a sofa, a desk, and a lamp.

A modern building with large windows and a patio area with white metal furniture.

A modern lobby with a reception desk, yellow chairs, a round table, and a large window.

14. Spark by Hilton Tupelo

6.3 km from North Mississippi Medical Center

Megan

￥15,574

￥17,014 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story hotel with a prominent entrance, a covered patio area, and a landscaped courtyard.

A lobby with patterned sofas, a coffee machine, a television, and a snack vending machine.

A spacious lobby with patterned seating, a stone accent wall, a flat-screen TV, and a snack bar.

A hotel room with a large bed, a desk, a chair, a TV, and a window with patterned curtains.

15. La Quinta Inn & Suites by Wyndham Tupelo

3.6 km from North Mississippi Medical Center

Annette

￥15,517

￥16,953 total

includes taxes & fees

Sep 27 - Sep 28

A Fairfield Inn & Suites Marriott hotel with a modern facade, a covered entrance, and a parking area.

An outdoor patio with round tables and chairs, potted plants, and a building with a modern design.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a sign indicating no lifeguard on duty.

16. Fairfield Inn & Suites by Marriott Tupelo

7.2 km from North Mississippi Medical Center

Kelly

￥16,288

￥17,795 total

includes taxes & fees

Oct 25 - Oct 26

A hotel with a covered entrance, a parking lot, and a clear blue sky.

A modern hotel lobby with a reception desk, an ATM, a dining area with chairs, and a kitchen area with a refrigerator.

A hotel room with two beds, a desk, and a chair.

A room with a sofa, a small table, and a chair.

17. Red Roof Inn Tupelo

3.6 km from North Mississippi Medical Center

Harley

￥9,924

￥10,843 total

includes taxes & fees

Oct 1 - Oct 2

A Courtyard Marriott hotel entrance at night with a well-lit facade, a covered parking area, and a landscaped garden.

A hotel room with a bed, a sofa, a desk, and a TV.

An outdoor patio area with a fire pit, seating, and a view of the interior through large windows.

A modern lobby with a reception desk, seating area, and a large abstract mural.

18. Courtyard By Marriott Tupelo

3.9 km from North Mississippi Medical Center

Keyunna

￥18,375

￥20,074 total

includes taxes & fees

Oct 4 - Oct 5

A reception area with a stone wall, a painting of autumn trees, and a potted plant.

A living room with a sofa, chairs, a coffee table, a flat-screen TV, a ceiling fan, and artwork on the walls.

A hotel room with a bed, two bedside tables with lamps, a sofa, and a small table.

A bathroom with a toilet, grab bars, a sink, and a mirror.

19. Americas Best Value Inn Tupelo Barnes Crossing

7.9 km from North Mississippi Medical Center

Lauren

￥11,079

￥12,814 total

includes taxes & fees

Sep 27 - Sep 28

A gym with treadmills, elliptical machines, and free weights.

A hotel room with a bed, a desk, a chair, a sofa, and a bedside table.

A swimming pool with a metal ladder, surrounded by a brick wall and stone tiles.

20. Comfort Inn Tupelo Central

3.6 km from North Mississippi Medical Center

Riesha

￥13,843

￥15,125 total

includes taxes & fees

Oct 18 - Oct 19

View all properties

Compare popular hotels close to North Mississippi Medical Center

Property	Star rating	Guest rating
Hotel Tupelo, a Wyndham Hotel	9.6 Exceptional 699 reviews	View
Holiday Inn Hotel & Suites Tupelo North by IHG	9.2 Wonderful 1,002 reviews	View
Candlewood Suites Tupelo North by IHG	8.6 Excellent 463 reviews	View
Hilton Garden Inn Tupelo	8.0 Very good 1,002 reviews	View
SureStay Hotel by Best Western Tupelo North	7.4 Good 255 reviews	View

Top North Mississippi Medical Center Hotel Reviews

Best Western Plus Tupelo Inn & Suites

10/10 Excellent

"Our stay was excellent, booked our room on the fly with no problems,room was very clean and comfy, staff was great even as late as we got there, breakfast was very good had a good buffet style. Getting to the motel is kind of a pain but Google maps gave very good directions to get to and leaving, this was our second stay here and it was very enjoyable. We did not ask for an upgrade on the room."

Comfort Inn Tupelo Central

10/10 Excellent

"Breakfast good"

Hilton Garden Inn Tupelo

8/10 Good

"Nice place with friendly and welcoming staff. Only complaint was our room remained warmer than I like at night despite turning the thermostat down, it still stayed around the same temperature."

Red Roof Inn Tupelo

8/10 Good

"na"

Spacious Historic Downtown home that sleeps up to 10!

10/10 Excellent

"The house was the perfect size for 3 adults and a dog. It's in a nice neighborhood and was very quiet."

Baymont by Wyndham Tupelo

8/10 Good

"N/A"

La Quinta Inn & Suites by Wyndham Tupelo

8/10 Good

"The room was clean and well prepared. The staff were very friendly and answered questions from check in to check out. We stayed at 5 different hotels on this vacation and the staff here were the most welcoming of us and our dog. Though others "welcomed" pets they were not very welcoming, but LaQuinta was different. There were some problems with breakfast equipment, but they were working to fix it."

Holiday Inn Express Hotel & Suites Tupelo by IHG

10/10 Excellent

"clean! very friendly staff! thank you"

Motel 6 Tupelo, MS - Downtown

8/10 Good

"d"

Frequently asked questions

What's the area like around North Mississippi Medical Center?

North Mississippi Medical Center is located in a welcoming area of Tupelo known for its major shopping area. If you're looking for a convenient place to stay, check out the 7 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to North Mississippi Medical Center?

Best Western Plus Tupelo Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.9 mi (6.3 km) from North Mississippi Medical Center. Other good options within a few miles include Red Roof Inn Tupelo and Holiday Inn Hotel & Suites Tupelo North by IHG.

How many hotels are there near North Mississippi Medical Center?

Expedia has 7 hotels and other accommodations within a mile from North Mississippi Medical Center.

If I need to cancel the hotel reservation for my stay near North Mississippi Medical Center, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best options available near North Mississippi Medical Center.

Where can I learn more about changing or cancelling my trip in the area near North Mississippi Medical Center?

For more information about rescheduling or cancelling your stay near North Mississippi Medical Center, click here.

What can I see and do near North Mississippi Medical Center?

You'll want to browse the exhibits at Elvis Presley Center and Oren Dunn City Museum. You might spend a leisurely day outdoors at Ballard Park and Elvis Presley Lake and Campground. Stopping by Cadence Bank Arena, Rob Leake City Park Tennis Center, or Cinemark Tupelo Movies 8 is a fun way to see all the area has to offer.

Find hotels near North Mississippi Medical Center, Tupelo from ￥10,116

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Treat yourself

Be picky

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Our top choices for North Mississippi Medical Center hotels

1. Hotel Tupelo, a Wyndham Hotel

2. Holiday Inn Hotel & Suites Tupelo North by IHG

3. Candlewood Suites Tupelo North by IHG

4. Hilton Garden Inn Tupelo

5. SureStay Hotel by Best Western Tupelo North

6. Studio 6 Suites Tupelo, MS - North

7. Motel 6 Tupelo, MS - Downtown

8. Scottish Inns

9. Holiday Inn Express Hotel & Suites Tupelo by IHG

10. Tru By Hilton Tupelo

11. Home2 Suites By Hilton Tupelo, Ms

12. Comfort Suites North Tupelo

13. Best Western Plus Tupelo Inn & Suites

14. Spark by Hilton Tupelo

15. La Quinta Inn & Suites by Wyndham Tupelo

16. Fairfield Inn & Suites by Marriott Tupelo

17. Red Roof Inn Tupelo

18. Courtyard By Marriott Tupelo

19. Americas Best Value Inn Tupelo Barnes Crossing

20. Comfort Inn Tupelo Central

Compare popular hotels close to North Mississippi Medical Center

Top North Mississippi Medical Center Hotel Reviews

Best Western Plus Tupelo Inn & Suites

Comfort Inn Tupelo Central

Hilton Garden Inn Tupelo

Red Roof Inn Tupelo

Spacious Historic Downtown home that sleeps up to 10!

Baymont by Wyndham Tupelo

La Quinta Inn & Suites by Wyndham Tupelo

Holiday Inn Express Hotel & Suites Tupelo by IHG

Motel 6 Tupelo, MS - Downtown

Frequently asked questions