Find hotels near Museum of Natural Science, Panama City from ￥4,951

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Our top choices for Museum of Natural Science hotels

Superior Double Room | Terrace/patio
La Isabela Suites

La Isabela Suites

La Isabela Suites
3.5 star property
San Felipe, 1.6 km from Museum of Natural Science
10.0 out of 10, Exceptional, (171)
"Wonderful charming property in the heart of the historic district. "
United States
Angela
La Isabela Suites
Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 2 km from Museum of Natural Science
10.0 out of 10, Exceptional, (146)
"Breakfast was so good , hotel was clean "
United States
ankit
The price is ￥24,448
￥26,894 total
includes taxes & fees
Jan 31 - Feb 1, 2026
Hyatt Regency Panama City
View from property
Hotel Plaza Herrera

Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
San Felipe, 1.7 km from Museum of Natural Science
10.0 out of 10, Exceptional, (14)
"Hotel Plaza Herrera is a real gem and the staff is all diamonds! We will be back! "
United States
Neal
The price is ￥43,325
￥47,791 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel Plaza Herrera
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
San Felipe, 1.6 km from Museum of Natural Science
9.8 out of 10, Exceptional, (259)
"Great location!"
United States
Erik
The price is ￥58,619
￥64,481 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hotel La Compañía Casco Antiguo
Exterior
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.8 km from Museum of Natural Science
9.8 out of 10, Exceptional, (568)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is ￥55,828
￥61,411 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Sofitel Legend Casco Viejo, Panama City
Outdoor pool
Yoo by Wynwood House

Yoo by Wynwood House

Yoo by Wynwood House
4.0 star property
Calidonia, 0.8 km from Museum of Natural Science
9.2 out of 10, Wonderful, (5)
"I will be back!"
United States
Jeffrey
The price is ￥24,164
￥32,070 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Yoo by Wynwood House
Breakfast and dinner served, international cuisine
Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo
3.0 star property
San Felipe, 1.7 km from Museum of Natural Science
9.6 out of 10, Exceptional, (108)
"Excellent location; friendly/helpful staff: clean/well-appointed rooms with lots of local character. "
United States
Brooke
Amarla Boutique Hotel Casco Viejo
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 1.6 km from Museum of Natural Science
9.6 out of 10, Exceptional, (195)
"Beautiful room Good location"
United States
Karla
The price is ￥47,163
￥51,879 total
includes taxes & fees
Jan 10 - Jan 11, 2026
La Concordia Boutique Hotel
Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated
Las Clementinas

Las Clementinas

Las Clementinas
3.5 star property
San Felipe, 1.5 km from Museum of Natural Science
9.4 out of 10, Exceptional, (172)
"Fabulous room and wonderful people that work there. "
Canada
Leah
The price is ￥21,674
￥23,841 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Las Clementinas
Front of property
Hotel San Felipe

Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 1.6 km from Museum of Natural Science
9.4 out of 10, Exceptional, (259)
"Great hotel, heart of old town and near great restaurants and sights. Extremely friendly and helpful staff. Highly recommended "
United States
Ashish
The price is ￥22,108
￥24,319 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hotel San Felipe
Front of property - evening/night
American Trade Hotel

American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 1.7 km from Museum of Natural Science
9.4 out of 10, Exceptional, (615)
"Beautiful location, excellent service. The food at their restaurant was decent, and the rooms were nice and clean"
United States
Kemmiel
The price is ￥45,481
￥50,029 total
includes taxes & fees
Jan 31 - Feb 1, 2026
American Trade Hotel
Interior detail
Canova

Canova

Canova
3.0 star property
Calidonia, 0.2 km from Museum of Natural Science
8.2 out of 10, Very Good, (132)
"Very close place to everything. Very affordable. "
United States
Alex
The price is ￥4,501
￥4,951 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Canova
Outdoor pool, free cabanas, sun loungers
Yoo Panama & Arts Tower

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista, 1.9 km from Museum of Natural Science
9.6 out of 10, Exceptional, (57)
"Ron was amazing and so was the property!"
United States
John
Yoo Panama & Arts Tower
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 2 km from Museum of Natural Science
9.2 out of 10, Wonderful, (1014)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel
Luxury Apartment | Balcony
Casco View Apartments

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana, 1.5 km from Museum of Natural Science
9.2 out of 10, Wonderful, (57)
"We live this property and stay here whenever we are in town."
United States
chris
Casco View Apartments
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 2 km from Museum of Natural Science
9.4 out of 10, Exceptional, (1006)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is ￥30,180
￥33,198 total
includes taxes & fees
Jan 31 - Feb 1, 2026
Bristol Panama, a Registry Collection Hotel
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 1.7 km from Museum of Natural Science
9.2 out of 10, Wonderful, (1000)
"Nice hotel in the historic center, excellent location for sightseeing and walking around at night."
United States
Antonio
The price is ￥55,572
￥61,129 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Central Hotel Panama Casco Viejo
Property entrance
Hotel Ojos del Rio

Hotel Ojos del Rio

Hotel Ojos del Rio
3.5 star property
Calidonia, 0.9 km from Museum of Natural Science
8.2 out of 10, Very Good, (914)
"Nice budget hotel."
United States
Turnell
The price is ￥6,729
￥7,521 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Ojos del Rio
Living area
Magnolia Inn

Magnolia Inn

Magnolia Inn
2.0 star property
San Felipe, 1.6 km from Museum of Natural Science
8.8 out of 10, Excellent, (421)
"Excelent location , friendly staff and cute hotel"
Canada
Renata
The price is ￥12,075
￥13,283 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Magnolia Inn
Apartment (3G) | Balcony
La Cuadra by Wynwood House

La Cuadra by Wynwood House

La Cuadra by Wynwood House
3.5 star property
El Chorrillo, 1.7 km from Museum of Natural Science
9.2 out of 10, Wonderful, (45)
"Love the property. You are right at the start of the nice part of casco viejo but the blocks around it are rough and ugly. The police are very prominent so it's safe but be on alert"
United States
Carlos
The price is ￥17,469
￥23,115 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Cuadra by Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Museum of Natural Science Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"It was a great stay! Staff were great but could be more friendlier. The only recommendation we have is for rooms to have shower cap. "
Farah 5-night trip
Posted 7 hours ago
Hotel Riu Plaza Panama

Hotels near other Museum of Natural Science attractions

Cinta Costera

4.5/5 (1,357 reviews)
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
See properties

National Bank House Museum

You can browse the exhibits at National Bank House Museum, a museum with a story of its own, during your travels to Panama City. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Museum of Natural Science?
Museum of Natural Science is located in a scenic area of Panama City known for its major shopping area and interesting historical sites. If you're looking for a convenient place to stay, check out the 405 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Museum of Natural Science?
Adjacent to Museum of Natural Science, Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. Other good options close by include Hotel Caribe and Canova.
How many hotels will I be able to find close to Museum of Natural Science?
Expedia has 405 hotels and other accommodations within a mile from Museum of Natural Science.
If I need to cancel the hotel reservation for my stay near Museum of Natural Science, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Add your dates and click on "Search", then filter by "fully refundable" to review top deals close to Museum of Natural Science.
Where can I learn more about changing or cancelling my trip in the area near Museum of Natural Science?
To access more information about rescheduling or cancelling your stay near Museum of Natural Science, head over to our customer service page.
What can I see and do near Museum of Natural Science?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and National Bank House Museum. Iglesia del Carmen, Panama Canal Railway, and Miraflores Locks are notable landmarks to explore if you're in the area. You can check out the local talent at National Theater, Amador Theater, and Anita Villalaz Theater.
How can I get to Museum of Natural Science?
Local metro stations include Estación Lotería and Santo Tomas Station. If you'd like to venture farther outside of the area, you may want a car rental for your journey.